Latest Interviews

MIc'd Up | Part 2: Pedro Domingos in Conversation with Eric Schmidt

Pedro Domingos, Eric Schmidt

Led by industry leaders like Bill Gates and Pedro Domingos, the event examines how converging advances in algorithms, data, and computing are shifting machine learning from rule-based programming to generalized intelligence. The presentation details critical hurdles in generalization and the urgent global talent shortage, while outlining transformative economic shifts where traditional hardware models face commoditization and new crowdsourced learning ecosystems emerge. Looking five to ten years ahead, the discussion predicts a workforce evolution where humans act as strategic captains alongside AI systems, enabling universal programming capabilities that could unlock a $5 trillion new world economy.

MIc'd Up | Part 1: A Conversation with Angela Ahrendts

Angela Ahrendts, Lucy Parker

Angela Ahrens is redefining Apple Retail as a global community hub by transforming physical locations into "hardware" designed for social connection rather than mere sales transactions. This strategic shift introduces the "Today at Apple" curriculum and "Creative Pros" roles across 500 stores to teach public classes in coding and arts, aiming to combat social isolation while leveraging the fact that half of recent Genius Bar visits were for education. By prioritizing human connection and meaningful work, the initiative has driven employee retention to 82% and positions the company to set new standards for corporate social responsibility through free lifelong learning opportunities.

A Conversation with Steven Mnuchin, Secretary, U.S. Department of the Treasury

Steven Mnuchin, Mike, Marie, Maria

The administration is pursuing a comprehensive tax reform agenda that seeks to accelerate economic growth to 3% annually by consolidating the tax code into a flat 15% corporate rate, eliminating most deductions, and removing the SALT deduction to broaden the tax base. While maintaining a stated goal of not cutting taxes for the wealthy through the Mnuchin Rule, the Treasury Department is negotiating with legislative leaders on the remaining details and preparing to use Senate reconciliation if bipartisan support cannot be secured. This fiscal strategy is complemented by parallel efforts to deregulate financial and energy sectors, reform GSEs to remove taxpayer risk, and advance reciprocal trade policies to support long-term revenue generation.

Scaling Growth | Gustaf Alstromer, YC Partner (formerly Airbnb) & Ed Baker (formerly Uber)

Gustaf Alstromer, Ed Baker

Ed Arons and Gustav Sorensen discuss their experience scaling growth teams at Uber, Airbnb, and Facebook, contrasting early viral tactics that exploited platform loopholes with sustainable strategies focused on retention and marketplace liquidity. The speakers detail how successful scaling requires aligning product and engineering functions, adapting paid acquisition to local constraints, and replacing short-term viral hacks with long-term investments in SEO, data science, and user experience optimization. Furthermore, they emphasize the necessity of institutionalizing experimentation to challenge assumptions, citing specific examples like copy adjustments in Japan and WeChat integration in China, while advocating for unified operational models that track acquisition, churn, and re-engagement separately.

Building Your Board | Glenn Kelman

Glenn Kelman, Selina Tobaccowala, James Slavitt, Jeff Markowitz, Mark Singer, Emily Melton, Austin Ligon, Reed, Julie Bornstein, Bob Milad, Jason, Janie, Scott, Chris Roski

Redfin CEO Peter van de Ven transformed his company's governance by shifting board relations from adversarial to collaborative, implementing strict communication protocols and off-site retreats to foster honest dialogue and strategic alignment. To ensure operational efficiency, the firm recruited board members based on peer-scale experience and mission alignment rather than corporate prestige, resulting in employed agents who are three times more productive than industry standards. This deliberate restructuring of founder-board dynamics and executive accountability has enabled Redfin to maintain higher Net Promoter Scores while generating hundreds of millions in annual revenue.

The Impact Investing Summit

Matthew Bishop, Lisa Ashford, Mark Campanale, Mark Goldring, Lutfey Siddiqi, Matthew Spencer, Tristram Stewart, Rod Schwartz, Arthur Wood, Mel Tam

In an Oxford-style debate regarding the primary agent for climate action, Lisa Ashford and Mark Campanali argued that investors and bankers can bypass political inertia to drive rapid decarbonization, while Matthew Spencer and colleagues contended that social movements and government policy are essential to establish the regulatory frameworks that make green investment viable. Despite pro-market arguments citing market failures and capital efficiency, the opposition team successfully countered by highlighting historical precedents where moral pressure and state intervention preceded financial shifts. Ultimately, the side opposing the motion won by persuading the audience to view political and social activism as the necessary "generals" that guide the "cavalry" of private capital.

Scaling Culture | Jason Kilar, former Hulu CEO

Jason Kilar

Jason, a corporate culture expert with twenty years of scaling experience at Disney, Amazon, and Hulu, argues that organizational values must be codified into repeatable mechanisms to survive growth beyond fifty employees. He details how Disney relied on explicit behavioral modeling and dedicated training institutions, while Amazon utilized written leadership principles and tangible awards to dismantle bureaucracy and enforce "Disagree and Commit" protocols. Additionally, Jason explains how Hulu leveraged provocative cultural documents to repel misaligned candidates and rigorously terminated high performers who violated core tenets, demonstrating that good intentions alone cannot sustain culture at scale.

From Startup to Scaleup | Sam Altman and Reid Hoffman

Sam Altman, Reid Hoffman

Originating from a Stanford class led by Reid Hoffman and Sam Altman, this event synthesizes the core principles of "blitzscaling" to address how technology startups can rapidly expand while maintaining network effects and organizational coherence. Through discussions on YC's continuity fund and hiring hierarchies that prioritize values over specific skills, the gathering outlines strategies for managing the chaos inherent in growing from twenty to over 500 employees. The session concludes by defining the critical shift from early-stage intuition to structured communication and capital efficiency, emphasizing that sustainable scaling requires leaders to explicitly balance inefficient growth with eventual profitability.

Why Functional Programming Doesn't Matter

John Hughes, Tony Hoare

Jane Street, a high-frequency proprietary trading firm executing millions of daily trades, attributes its engineering success to OCaml's expressive static types rather than traditional functional features like laziness or strict purity. This type system enforces correctness by eliminating null pointer exceptions, forcing logic updates at compile-time to prevent bugs, and encoding business invariants to exclude impossible states. Consequently, the firm prioritizes predictable performance and verifiable clarity to protect its capital against errors, viewing advanced type systems as a more critical asset than higher-order functions or declarative purity.

Incremental

Sebastian

Sebastian, a developer at Jane Street, presents the Incremental library, a self-adjusting computation system that enables dynamic dependency graphs for high-performance trading, risk modeling, and user interfaces. The discussion details the library's eight-version evolution, which resolved critical memory leak and performance bottlenecks by replacing heap-based sorting with a partial order system and implementing explicit observer tracking. These architectural improvements, combined with GADTs and CPU cache optimizations, allow the system to execute minimal necessary updates while supporting complex dynamic graph topologies.

Drew Houston : How to Build the Future

Drew Houston, Sam Altman, Drew Haust

Drew Houston co-founded Dropbox in 2007 after Y Combinator rejected his initial venture, forming a partnership with Arash Todd to build a file-syncing service that validated market demand through a viral referral program. The company evolved from a storage tool into a collaboration platform by strategically pruning unsuccessful products like Carousel and Mailbox to focus on its core value proposition. Houston subsequently shifted his leadership style from technical coding to strategic management, utilizing insights from literature and advisors to navigate scaling challenges while maintaining a private status to avoid public market volatility.

MIT 6.S094: Deep Learning for Human-Centered Semi-Autonomous Vehicles

Researchers are collecting billions of high-speed video frames from semi-autonomous Teslas to train deep learning models that detect critical driver metrics such as body pose, gaze direction, and cognitive load. By shifting from fully supervised to semi-supervised annotation strategies, the team achieves an 84-fold reduction in human effort while accurately identifying micro-saccades and emotional cues to overcome current privacy and trust barriers. This data-driven approach aims to replace static crash test assumptions with dynamic occupant monitoring, ultimately enabling vehicles to adapt passive safety systems based on real-time human behavior.

Pitch Practice with Paul Buchheit and Sam Altman at Startup School SV 2016

Paul Buchheit, Sam Altman, Jenna Brown, Kelli Thomas-Drake

Sam Altman evaluated two distinct startups, a shipping marketplace that reduced booking times from weeks to seconds and a healthcare aggregator unifying fragmented patient records, to demonstrate high-pressure pitch dynamics. He subsequently re-pitched each venture to highlight critical success factors, including ShipperMax's potential for a natural monopoly in a $150 billion market and My Purple Folder's urgent need for narrative clarity despite strong organic growth. The session underscored that founders must clearly articulate their specific exception to the "default no" investor rule within thirty seconds to secure meaningful follow-ups or funding.

Lunch Plenary: The Quest for Meaningful Lives

James Morgon, Michael Milken, Katie O'Reilly

The Milken Institute London Summit, featuring keynote remarks by Chairman Michael Milken, convened to address critical global challenges ranging from US wealth disparity and labor force exclusion to rapid industry disruption by automation and biotechnology. Amidst a backdrop of collapsing financial commissions, plummeting genomics costs, and significant geopolitical shifts in bioscience, the event highlighted how financial innovation and precise regulation can stimulate economic growth while mitigating social instability. Sponsors including WorldQuant and the Gates Foundation supported the forum as it urged stakeholders to leverage capital markets and emerging technologies to expand access, create jobs, and address the psychological needs of an increasingly isolated population.

Marc Andreessen at Startup School SV 2016

Marc Andreessen

Andreessen Horowitz operates on a founder-centric philosophy, deploying an internal infrastructure of 85 professionals and experienced partners to provide comprehensive "founder superpowers" that distinguish it from traditional venture capital models. The firm executes a highly selective institutional fundraising funnel, reviewing thousands of referrals annually to invest in roughly 1% of candidates through rigorous due diligence and strategic network integration. Currently, a16z maintains high-conviction investment thesis positions in artificial intelligence, biological convergence, and autonomous transportation, while advising founders to pursue long-term infrastructure plays despite market timing paradoxes.