Latest Interviews
Showing 676–690 of 1,991 transcripts.
Clear all filters- Milken Institute59 min
Things That Will Blow Your Mind | Milken Institute Global Conference 2024
Richard Sandler, Lisa Dyson, David Ferrucci, Keith Gottesdiener, Michael Mager
This panel features David Ferrucci, Michael Major, Lisa Dyson, and Dr. Keith Gottensteiner discussing the commercial maturation of neuro-symbolic AI, high-resolution brain-computer interfaces, atmospheric protein synthesis, and precision prime editing. Each expert details how their respective technologies—ranging from zero-hallucination enterprise reasoning and 80-word-per-minute speech decoding to carbon-negative food production and safe gene therapies—are transitioning from theoretical research to deployed clinical and industrial solutions. Collectively, the session underscores a strategic shift toward reliable computation and the integration of software with physical matter while emphasizing the ethical imperative to align these advancements with human well-being.
John Coogan, EIR at Founders Fund, Founder of Soylent & Lucy
Former Soylent founder John Coogan launched Lucy in 2016 to introduce nicotine replacement products into a market where regulatory barriers now make entry nearly impossible without massive capital. The company successfully achieved profitability by targeting older demographics with a conservative strategy that avoids youth-culture marketing while competing against big tobacco giants like Altria. Coogan also uses this venture to critique the venture capital ecosystem's over-reliance on massive scale-ups, advocating instead for sustainable micro-businesses and practical AI applications.
- Milken Institute57 min
The Geopolitics of AI | Global Conference 2024
Erik Schatzker, Karen Kornbluh, Eva Maydell, Anne Neuberger, Karen Pierce, Kevin Rudd
This panel examination characterizes the U.S.-China relationship as a strategic AI competition where the United States maintains an edge in foundational models while leveraging export controls to slow Chinese semiconductor access. The discussion contrasts Western regulatory approaches, such as the EU AI Act, against China's state-driven dominance, while emphasizing a shift toward plurilateral governance among democracies to mitigate risks like election interference and disinformation. Ultimately, experts argue that long-term competitiveness hinges on public-private partnerships and alliance cohesion rather than multilateral frameworks that could empower adversarial regimes.
- Sequoia Capital52 min
Klarna CEO Sebastian Siemiatkowski on Getting AI to Do the Work of 700 Customer Service Reps
Sebastian Siemiatkowski, Sonya Huang, Pat Grady
Klarna CEO Sebastian Gunnarsson leveraged a direct partnership with OpenAI to transform the payments platform's dispute resolution from a 14-minute human process to a two-minute autonomous AI system, resulting in a $40 million annual profit increase and the elimination of 700 contracts. Beyond customer service, the company has centralized its operations into a proprietary knowledge graph to power an internal chatbot named Kiki while simultaneously replacing legacy enterprise software to accelerate marketing campaigns from months to days. Gunnarsson frames this strategic shift not as a total replacement of human roles but as a necessary evolution to enforce higher documentation standards and create a "digital financial assistant" that proactively drives savings for consumers.
- Milken Institute59 min
The Rising AI Economy: A New Era in Tech | Milken Institute Global Conference 2024
Nicole Valentine, Seth Boro, Les Borsai, Sachin Dev Duggal, X Eyeé, Martin Fichtner, Sachin Chakrabarti
A panel of industry leaders including Sachin Chakrabarti, Seth Sternberg, and X Fortuna evaluated the current AI landscape as a nascent broadband era grappling with severe infrastructure energy demands, algorithmic biases, and significant regulatory gaps. While experts identified transformative benefits in democratizing literacy and enhancing cybersecurity, they simultaneously highlighted critical risks ranging from lethal misclassifications by predictive policing algorithms to the potential for LLMs to recommend nuclear strikes. The discussion concluded by contrasting short-term market inefficiencies where speculative startups are overvalued against a long-term vision requiring responsible governance to ensure AI empowers future generations without exacerbating geopolitical or ethical divides.
- Milken Institute58 min
Traversing Real Estate Realities | Milken Institute Global Conference 2024
Ted Seides, Jase Auby, Maggie Coleman, Joshua Morris, Tim Sloan, Joshua Weintraub
Leading institutional investors and asset managers converged to analyze a commercial real estate market defined by a dislocation between elevated interest rates and slower fundamental growth, creating distinct opportunities in data centers, single-family rentals, and distressed senior credit while navigating significant risks in oversupplied office sectors. Speakers highlighted how a generational housing shortage and a looming "wall of maturities" for $2.6 trillion in commercial loans are driving a structural shift where private non-bank lenders replace exiting regional banks to fund high-yield strategies. The panel concluded that prioritizing use-based assets with defensive demographics over traditional property classifications offers a more resilient path through the current higher-for-longer rate environment, provided investors maintain strict valuation discipline against cyclical volatility.
- Milken Institute1h 1m
The Next Wave of Immunotherapy and Cancer Treatments | Milken Institute Global Conference 2024
Marc Hurlbert, Gina Carithers, Friedrich Graf Finckenstein, Anusha Kalbasi, Connie Pfeiffer, Sunil Verma, Frederick Finckenstein, Neil Verma, Anusha Singhal
Major research organizations like the Melanoma Research Alliance and the Prostate Cancer Foundation have funded over $1 billion in studies that pioneered immune checkpoint inhibitors and novel T-cell therapies for melanoma and prostate cancer. Recent advancements include the approval of Iovance's tumor-infiltrating lymphocyte treatment for solid tumors and the development of bispecific agents that reduce manufacturing delays, though challenges regarding high costs, autoimmune side effects, and the need for broader genetic screening persist. Clinical strategies are shifting toward neoadjuvant trials and combination therapies with antibody-drug conjugates to improve patient outcomes before standard care options are exhausted.
- All-In Podcast1h 16m
Trump assassination attempt, Secret Service failure, Inside the RNC, VC liquidity problem
Trump, Chamath, Jason, Friedberg, Nick, Freeburg
Following a failed assassination attempt by Thomas Matthew Crooks that killed one attendee and injured others, the Republican National Convention solidified a coalition between MAGA populists and tech interests by selecting J.D. Vance as Donald Trump's vice-presidential running mate. The hosts analyzed the event's security failures, debated the impact of political rhetoric on the violence, and examined the administration's potential shift toward isolationist trade policies and regulatory changes regarding Big Tech. Simultaneously, the discussion highlighted significant venture capital developments, including Stripe's liquidity deal and Google's potential acquisition of Wiz, while predicting President Biden's imminent withdrawal from the race due to declining donor confidence.
- Milken Institute1h 1m
Private Equity Delivering Value | Milken Institute Global Conference 2024
John Bowman, Chris Emanuel, Martin Escobari, Jacob Kotzubei, Collin Roche, Bridget Walsh
Driven by a surge to $22 trillion in assets and a prolonged IPO drought, the private capital sector is undergoing a structural shift from financial engineering to intensive operational transformation. Leading firms like Platinum Equity, GTCR, and GIC are deploying specialized teams to execute immediate CEO changes, leverage GenAI for due diligence, and prioritize distributions over returns, while simultaneously navigating a market bifurcation that threatens non-adaptive players. This evolving landscape forces a consolidation of the 10,000 existing general partners as asset managers adopt interventionist strategies to maximize value in a high-interest-rate environment where traditional holding periods are being redefined.
- Milken Institute1h 1m
What's Trending in MedTech? | Milken Institute Global Conference 2024
Conor Hale, Kelvin Baggett, Andrew Fish, Nada Hanafi, Ryan Lakin, Michelle Tarver
Facing a constrained 2023 investment climate, the industry is pivoting from speculative hype to value-driven innovations in women's health, AI, and genomic technologies that prioritize clear patient outcomes. Regulatory frameworks like the FDA's TAP and new real-world evidence protocols are accelerating approvals while shifting focus toward patient-integrated design and equitable access. Leaders such as Abbott and J&J are now embedding affordability and diversity into R&D, ensuring devices function as intuitive, home-based solutions that address systemic provider shortages and health inequities.
- Milken Institute1h 1m
Banks Stepping Out, Private Credit Stepping In | Milken Institute Global Conference 2024
John Bowman, Jeffrey Aronson, Marianna Fassinotti, Gregory Geiling, Peter Gleysteen, Drew McKnight
The private credit market has evolved from a niche financing tool into a $2.2 trillion "big tent" asset class, driven primarily by regulatory pressures like the Basel Endgame that force banks to offload capital requirements while retaining origination roles. This structural shift has fostered a complementary partnership model where global banks leverage private capital for risk transfer and flexibility, resulting in robust credit quality despite a temporary pause in corporate activity due to high interest rates. As the industry navigates the next economic cycle, focus is shifting toward downside protection, specialized asset management, and the emerging secondary market to address the sector's lack of full stress testing since the Global Financial Crisis.
- Sequoia Capital1h 7m
Reflection AI’s Misha Laskin on the AlphaGo Moment for LLMs | Training Data
Misha Laskin, Ioannis Antonoglou, Stephanie Zhan, Sonya Huang, Peter Abbeel, Rich Sutton, Joe Bardeen, Einstein, Michael Jordan
Founders Misha Laskin and Giannis, leveraging their DeepMind and Google experience, established Reflection AI to solve the reliability bottleneck in autonomous agents by replacing heuristic prompting with scalable search and reinforcement learning. The company addresses the "depth problem" in current LLMs by treating post-training as an AlphaGo-style pipeline that minimizes error accumulation to transition task completion rates from approximately 13% to near-perfect reliability. With a strategic vision targeting digital AGI within three years, Reflection aims to deploy universal agents capable of complex multi-step reasoning while prioritizing pragmatic safety through operational consistency.
- Milken Institute1h 0m
Transformative Philanthropy and Innovation | Milken Institute Global Conference 2024
Melissa Stevens, Pablo Legorreta, Strive Masiyiwa, Louise Richardson, Mark Walter
CEO Mark Walter, Strive Masiwa, Dame Louise Richardson, and Pablo Legareta convened to define transformative philanthropy as high-risk capital that drives systemic change in healthcare, education, and conservation. The panel detailed specific strategies such as Legareta's medical therapies for transplant patients, Walter's vocational schools in Chicago, and community-integrated conservation models in Zimbabwe that successfully reduced rhino poaching. Ultimately, the leaders agreed that effective philanthropy must prioritize sustainable governance and local resource mobilization to mitigate polarization and create a self-sustaining future.
- Milken Institute59 min
Leading in the Generative AI Revolution | Milken Institute Global Conference 2024
Sara Eisen, Greg Brown, Arvind Krishna, Thomas Kurian, Janet Truncale, Sharmini Peries, Janet Napolitanovich, Thomas Kaplan, Nicole Sullivan, Arvind K.
Prominent industry leaders including Arvind Krishna, Thomas Kurian, and Greg Clark characterize the AI sector as being in its early developmental stage, emphasizing a strategic pivot from immediate productivity gains to scalable deployment across public safety, healthcare, and enterprise operations. These executives detail a multi-cloud infrastructure approach where organizations like Motorola Solutions and EY leverage edge AI and "human-in-the-loop" frameworks to address data sovereignty, bias, and trust barriers while augmenting workforce capabilities rather than displacing them. The panel concludes that future growth depends on navigating light-touch regulatory environments and combating misinformation through rigorous data management and open-source collaboration.
- Jane Street1h 4m
From the Lab to the Trading Floor: Designing for Expert Users with Erin Murphy
Erin Murphy discusses her evolution from creating data visualization portals at NASA's Jet Propulsion Laboratory to implementing formal UX processes at Jane Street, where she addresses the unique needs of technical experts requiring high information density and keyboard-driven workflows. By prioritizing functional clarity over consumer aesthetics, Murphy leads initiatives that transition complex legacy tools into web-based interfaces while leveraging informal, ad-hoc user observations to maintain design agility within a rapidly scaling engineering environment. Her approach emphasizes recruiting domain-expert designers who can partner with engineers to solve high-complexity problems, ultimately aiming to bridge the gap between graphical usability and the composability of command-line interfaces.