Latest Interviews
Showing 1–15 of 1,042 transcripts.
Clear all filters- Y Combinator56 min
How To Design In The Agent Era
Led by Stephen Haney, Paper is an AI-native design platform currently ranking as the third most-used tool behind Figma and Sketch, utilizing a native HTML and CSS rendering engine to facilitate precise agent collaboration. The application distinguishes itself by treating code as the single source of truth, offering features like direct React component handoff and an MCP server that allows autonomous agents to manipulate local repositories and design canvases. While the team prioritizes human curation to maintain design quality against common AI aesthetic pitfalls, the platform is rapidly evolving into a visual coordination layer for the broader agent ecosystem by integrating tools like Paper Shaders and multi-model image generation.
- Milken Institute45 min
AI Infrastructure at Scale: Financing the Power-Constrained Grid | Global Conference 2026
Brian Sullivan, Lucy Heintz, Douglas Kimmelman, Karl Kuchel, Rajit Nanda, Michael Zeltkevic, Doug Kimmel, Carl Cuscelli, Lucy Hines
Projected to approach one trillion dollars in global capital expenditures, the AI energy transition is being driven by hyperscalers utilizing long-term power purchase agreements to de-risk infrastructure financing amid rising electricity costs. As the industry shifts from a focus on speed to market to speed to power, data center locations are increasingly dictated by the immediate availability of reliable energy and data sovereignty constraints, with nations like Saudi Arabia positioning themselves as strategic inference hubs. While supply chain advantages and government permitting acceleration are accelerating deployment, the sector faces significant consolidation risks and financing hurdles for unproven storage technologies as the race for compute capacity intensifies.
- Milken Institute55 min
The Tech Supercycle: Where Capital Meets Innovation | Global Conference 2026
Daniel Koffmann, Marlene Garayzar, Scott Sobel, Francis Suarez, André Vellozo, Marlena Górezar, Andre Veoso
Scott Sobel of Valor Capital Group and Marlena Górezar of Story analyze the Latin American venture landscape, highlighting a rebound in investment driven by deep talent pools and resilient fintech unicorns that achieve profitability through proprietary AI models. Former Miami Mayor Francis Suarez and Andre Veoso of Drumwave discuss how physical safety, regulatory deregulation like Brazil's Pix system, and renewable energy infrastructure are establishing the region as a secure hub for reverse innovation and AI sovereignty. Together, the speakers illustrate a strategic pivot toward capital efficiency and data ownership, positioning Latin American firms to capitalize on valuation arbitrage as they expand globally.
- Milken Institute56 min
Inside the New Sports Economy: Innovation, Partnerships, & Global Expansion | Global Conference 2026
Jon Schwartz, David Abeles, Heather Brooks Karatz, Jeff Gordon, Ben Kennedy
NASCAR and golf leaders are redefining their industries through experiential festival models, massive digital gaming partnerships, and the strategic repurposing of venues for year-round mixed-use development. With new playoff formats and unique event locations like the upcoming San Diego military base race, the sports aim to capture first-time fans while leveraging simulation technology and female demographic data to drive engagement. Industry experts predict significant consolidation in golf by 2026 and emphasize that authentic values will remain essential for sustaining long-term revenue in an increasingly diverse and digital sports economy.
- Y Combinator49 min
Waymo Co-CEO Dmitri Dolgov: The Demo Is Only 1% Of The Work
Waymo has advanced its fully autonomous fleet to operate 500 weekly trips across 15 U.S. cities, achieving a safety record 17 times better than human drivers through a multimodal sensor architecture and a foundation model utilizing both fast geometric reactions and slow semantic reasoning. The company addresses the unique challenges of physical AI by integrating real-world data into a generative simulation ecosystem that creates rare edge cases for training, while its "Safety and Readiness Framework" rigorously validates performance to ensure public trust and regulatory compliance. Looking ahead, this structural augmentation and flywheel of agent, simulator, and critic data positions Waymo to expand its technology beyond personal vehicles into trucking and broader physical applications.
- Milken Institute1h 3m
Things That Will Blow Your Mind | Global Conference 2026
Richard Sandler, Ali Agha, Erin Blanton, Bentzion Levinson, Geoffrey von Maltzahn
This panel featured four innovators presenting distinct AI-driven solutions: Lila Sciences deployed autonomous laboratories to accelerate biotech and material discoveries, Field AI introduced hardware-agnostic robotics for extreme environments, Heaven Aerotech developed hydrogen-powered endurance drones for strategic defense, and Carbon Mapper utilized satellite spectrometry to identify and mitigate global methane super-emitters. Collectively, these breakthroughs demonstrate a shift from conversational AI to embodied, physical intelligence capable of operating 24/7 to solve critical challenges in labor shortages, climate change, and geopolitical security. The discussion concluded with a unified call for the West to reindustrialize and scale automation to prevent falling behind China's rapid advancements in scientific and military capabilities.
- Y Combinator1h 16m
Kernels and Chips: Cursor, NVIDIA, and Meta Researchers on GPU Performance | YC Paper Club
Stuart Sul, John, Francois Chaubard, Jon Saad-Falcon, Mark Saroufim, Misha Smelyanskiy, Brennan Shacklett
The event synthesizes critical industry shifts toward specialized ASICs and disaggregated architectures that separate training and inference workloads to maximize intelligence per watt. Technical deep dives highlight breakthroughs in multi-GPU kernel optimization and local inference, demonstrating that consumer accelerators can now deliver nearly 90% of frontier model utility while reducing energy costs by 70%. These innovations collectively address systemic bottlenecks in network communication and latency, establishing a roadmap for distributed, cost-efficient AI ecosystems that minimize reliance on centralized cloud resources.
- All-In Podcast1h 9m
The Robot Episode: Four Leaders on What's Coming
Dr. Péter Fankhauser, Bernt Børnich, Amanda McMaster, Jonathan Hurst, J-Cal
Leading robotics firms including Anybotics, Boston Dynamics, and Agility Robotics have collectively deployed over 1,000 specialized units globally to replace humans in hazardous industrial settings, prioritizing data sovereignty and ISO cybersecurity standards to avoid reliance on Chinese hardware. These companies are currently transitioning from pure detection to scalable autonomy through platform-based ecosystems and cost reductions, with humanoids targeting a $40,000 price point and quadrupeds enabling continuous 24-hour monitoring in extreme environments. While immediate returns focus on safety and leak prevention, the industry anticipates a hard take-off in manufacturing capabilities within a decade as foundational AI models enable complex, multi-arm manipulation without physical safety barriers.
- Y Combinator50 min
Blake Scholl: How 50 People Built a Supersonic Jet
Founded by Blake Scholl in 2014, Boom Supersonic successfully developed the XB-1, the first privately built jet to break the sound barrier, using a lean team and software-driven engineering to overcome decades of aviation stagnation. This historic flight directly catalyzed a shift in US federal policy, prompting an Executive Order that legalized supersonic flight over land and clearing the path for the upcoming Overture airliner. By vertically integrating manufacturing and creating revenue through ground-based engines, the company aims to double global travel speeds while eliminating the traditional sonic boom barrier.
- Milken Institute52 min
Tradewinds: Navigating Economic Uncertainty | Global Conference 2026
Gerard Baker, Whitney Baird, Xavier Bettel, John Denton, Francisco Pérez Mackenna, Michael Roberts, Jerry Baker
A global economic panel consensus identifies a critical inflection point where geopolitical volatility and policy unpredictability are driving nearly $250 billion in annual lost activity while compelling nations to prioritize supply chain resilience over pure free trade. Amidst rising food security threats from conflicts in the Middle East and evolving US-China de-risking strategies, leaders are exploring plurilateral arrangements and technological solutions to manage these disruptions. Ultimately, the event highlights a shift toward strategic autonomy and green energy innovation as essential mechanisms to mitigate inflationary pressures and narrow the widening gap between the Global North and South.
BlackRock's Tony Kim on AI's Next Winners? Chips, Memory, Robotics & Quantum
Kim outlines a fundamental shift in the global technology sector where a $30 trillion hardware-centric economy is driven by a 10,000x increase in compute density and severe memory shortages known as the "Rampocalypse." Leading institutions are responding through silicon co-design and gigawatt-scale energy infrastructure while BlackRock allocates capital toward immediate compute needs and long-term bets on quantum and orbital data centers. The narrative concludes with strategic observations on China's robotics acceleration and the restructuring of traditional enterprises into AI-native entities through proprietary token flow architectures.
- Stanford Online56 min
Stanford MS&E435 Economics of the AI Supercycle | Spring 2026 | The GPU Economy
Sunny Madra, Brad Gerstner, Apoorv Agrawal
Brad Gerstner of Altimeter Capital and Grok co-founder Sonny Maduro outline a transformative shift where AI distribution costs are now compute-intensive, driving the integration of deterministic architecture with Nvidia's GPU ecosystem to accelerate inference. This strategic fusion, which led to Nvidia's $20 billion acquisition of Grok, enables a 2.5x increase in token generation while addressing critical power and memory constraints to support the transition from chat-based tools to autonomous agents. As the industry approaches Artificial General Intelligence faster than anticipated, the convergence of these hardware innovations and emerging regulatory frameworks aims to redefine global economic output and the future value of human labor.
SemiAnalysis, Altimeter, Nebius, Glean.. 12 Hot Takes From Biggest Names in AI
Dylan Patel, Qasar Younis, Apoorv Agrawal, Arvind Jain, Ariel Cohen, CJ Desai, Gil Feig, Nikhil Benesch, Barak Kaufman, Max Junestrand, Marc Boroditsky, Laura Diorio, Kasser, Mark
RAISE Paris marked a decisive industry shift from speculative hype to enterprise-grade cost reconciliation, as buyers now demand clear ROI and physical AI adoption outpaces volatile large language model growth. Key figures including Applied Intuition's Kasser and analysts from Altimeter Research warned of an impending market bust driven by unsustainable spending, while companies like Navan and TurboPuffer demonstrated new economic models focused on profitability and reduced inference costs. The event concluded with a consensus that success requires resilient multi-model strategies, robust data layers, and a global expansion mindset to navigate rising hardware prices and geopolitical energy constraints.
- Stanford Online49 min
Stanford MS&E435 Economics of the AI Supercycle | Spring 2026 | Applications, AI in Life Sciences
Eric Kauderer-Abrams, Apoorv Agrawal, Eric Abrams, Josh
Chai Discovery and Anthropic are establishing a new drug discovery paradigm by serving as tool providers that convert biological engineering from a trial-and-error art into a scalable, AI-driven discipline. By integrating large language models with wet-lab validation, these firms aim to compress the traditional ten-year development cycle into five years while democratizing research capabilities for individual scientists. The convergence of these technologies, supported by massive data generation and strategic partnerships with major pharmaceutical companies, positions AI-native infrastructure as the critical lever for the United States to compete globally in biotech.
- Milken Institute57 min
The Future of Decision Intelligence | Global Conference 2026
Dan Primack, Stephanie Guild, Paul Liberman, Brian Quintenz
Former CFTC Commissioner Brian Quintenz, Robinhood CIO Steph Gild, and DraftKings President Paul Lieberman discussed how regulated prediction markets like Kalshi aggregate disaggregated information into high-frequency sentiment signals that surpass traditional polling and institutional research. The panelists distinguished these federally licensed derivatives from unregulated gambling by highlighting their role in price discovery, the use of real capital to reduce emotional bias, and robust surveillance systems that deter insider trading. Looking ahead, the speakers anticipate expanding contract categories into corporate earnings and geopolitical events while maintaining that these tools serve as complementary data points for investment portfolios rather than sole decision-making authorities.