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  1. Milken Institute59 min

    Digital Assets at the Crossroads: From Promise to Permanence | Middle East & Africa Summit 2025

    Michael Piwowar, Adeeb Ahamed, Yoni Assia, Yuval Rooz, Joanne Strain, Adib Ahmed

    Geopolitical fragmentation is driving a shift toward sovereign regional payment ecosystems while AI integration and configurable privacy protocols like the Canton Network address critical interoperability challenges. Simultaneously, legal frameworks in jurisdictions such as the UAE and UK are classifying digital assets as a distinct form of property, enabling the tokenization of trillions of dollars in traditional illiquid assets onto blockchain rails. This regulatory evolution, paired with the rise of stablecoins as primary treasury instruments, is forcing traditional capital markets to adopt 24/7 trading models and modernize legacy infrastructure to meet the demands of a crypto-native generation.

  2. The Economist8 min

    How OSINT has given Ukraine a strategic advantage

    Will Marshall, Shashank Joshi

    The company initiated direct data sharing with Ukrainian military officials and former spy chief Kyrylo Budanov to provide strategic intelligence on Russian operations in the Black Sea and deep territory. While an ethics committee reviews government requests to ensure transparency, the founders emphasize that their role involves guiding technology use through selective partnership rather than claiming neutrality in conflicts with distinct societal impacts. Despite facing Russian cyber threats and being viewed as a hostile entity, the fleet maintains operational resilience through a disaggregated architecture that ensures continuous service even when individual satellites are compromised.

  3. Sourcery with Molly O'Shea23 min

    Data Centers in Space? Armada’s CEO on SpaceX and the Edge

    Dan Wright, Molly O'Shea

    Armada, funded by over $200 million, deploys modular AI factories to bring hyperscale computing to remote and hostile environments, effectively bridging the digital divide in regions lacking traditional infrastructure. Strategic alliances with key entities like SpaceX, OpenAI, and Microsoft enable the company to integrate edge connectivity and proprietary models into diverse sectors ranging from military operations on aircraft carriers to disaster response in the Arctic and Saudi desert. By prioritizing rapid deployment of American-led AI stacks, Armada aims to secure global data sovereignty and expand its footprint into critical industries such as energy and defense through 2026.

  4. All-In Podcast2h 15m

    The Future of Everything: What CEOs of Circle, CrowdStrike & More See Coming in 2026

    Jeremy Allaire, George Kurtz, Adam Goldstein, Chase Lochmiller, Mike Green

    In a discussion featuring Jeremy Allaire of Circle and Brian Armstrong of Coinbase, industry leaders forecast that 2026 will mark a pivotal shift toward institutional stablecoin adoption driven by new regulatory frameworks and falling interest rates. Concurrently, security experts like George Kurtz highlight how AI has accelerated cyber threats while aviation pioneers such as Adam Goldstein of Archer Aviation anticipate commercial VTOL operations by summer 2026 following accelerated federal certification. Meanwhile, Crusoe's Chase Locke Miller details a strategic pivot to energy-abundant regions, securing massive AI infrastructure capacity through stranded renewables and small modular reactors to support the surging demand from hyperscalers.

  5. Milken Institute51 min

    Innovation in Artificial Intelligence and Manufacturing | Middle East & Africa Summit 2025

    Hunny Bhagchandani, Kaushik Burman, Frans Cronje, Songo Didiza, Guy Diedrich, Mostafa El-Ghorab, Kweilin Ellingrud, John Kamara, Francis Kariuki, Ayaan Mohamed, Editha Mshiu, Emily Musil, Nneile Nkholise, Derick Nwumfor Chunga, Michael Milken

    Launched in 2021, the Milken-Mozzeppe Innovation Prize's fourth "AI and Manufacturing" track selected ten semi-finalists from over 12,000 global applicants to compete for a $1 million grand prize at the May 2026 Milken Institute Global Conference. A panel of industry experts evaluated these contenders based on commercial viability and technological depth, with five companies including Digitech Oasis and Blee Glee Management Company advancing to the final round while all ten recipients received $50,000 seed awards. Strategic commentary from leaders such as Michael Milken underscored the program's role in catalyzing local African manufacturing, creating youth jobs, and disintermediating global industries through AI-driven innovation.

  6. All-In Podcast1h 6m

    Dr. Mehmet Oz on Fixing American Healthcare + Fraud | Live from Davos

    Dr. Mehmet Oz, Dr. Oz, Chamath, Jason, Friedberg

    Dr. Mehmet Oz's summary outlines a Trump administration strategy to overhaul U.S. healthcare by bypassing legislative gridlock through administrative rulemaking and leveraging AI to boost clinical efficiency while enforcing strict fraud detection. Central to this approach is a radical reduction in drug costs via direct negotiations with manufacturers like Novo Nordisk and Eli Lilly, alongside a $50 billion rural transformation fund deploying telemedicine and autonomous technology. The administration projects these measures will eliminate billions in waste, stabilize Medicare sustainability, and fundamentally reshape the system by prioritizing subject-matter expertise over traditional political staffing.

  7. All-In Podcast1h 35m

    Coinbase CEO's Top 3 Crypto Trends for 2026 + More from Davos!

    Brian Armstrong, Andrew Feldman, Jake Loosararian, Jason Calacanis

    At a recent World Economic Forum panel, industry leaders Brian Armstrong, Andrew Feldman, and Jake Lucerarian detailed a strategic shift toward regulatory compliance, hardware acceleration, and industrial robotics. Armstrong outlined how new U.S. stablecoin legislation and favorable administration policies are driving institutional adoption, while Feldman described Cerebras's Wafer-Scale Engines as a critical solution to power and latency bottlenecks facing AI infrastructure. Simultaneously, Lucerarian highlighted how Gecko Robotics is leveraging proprietary data and government defense contracts to automate high-value physical inspections, underscoring a convergence of AI, energy constraints, and tangible economic infrastructure.

  8. Milken Institute45 min

    Real Estate in a Repriced World | Middle East & Africa Summit 2025

    Caitlin MacLean, Ian Livingstone, Yasseen Mansour, Sue Nickason, Yassine

    This event analyzed divergent real estate trajectories across key jurisdictions, highlighting the UAE's rise as a tax-efficient migration hub while detailing how Egyptian developers are countering inflation through premium branding and mixed-use revenue streams. Attendees examined strategic adaptations to global volatility, including Panama's fast-track privatization laws, Cayman Islands' self-sufficient infrastructure models, and the specific risks of surging data center debt and hospitality distress in the US. The discussion concluded that long-term success now requires rigorous due diligence on climate resilience and legal stability to navigate a market where speculative gains have given way to sustainable, experience-driven asset management.

  9. Goldman Sachs25 min

    Anastasia Soare: Building a Billion-dollar Beauty Brand

    Anastasia Soare, Meena Flynn

    Anastasia Sorey, founder and CEO of Anastasia Beverly Hills, joined Goldman Sachs to recount her journey from navigating communist Romania to building a billion-dollar beauty empire through a philosophy of mastering craft and prioritizing client well-being. Sorey detailed how she leveraged resilience, a self-developed product line, and strategic partnerships with retailers like Nordstrom and media figures like Oprah Winfrey to scale her brand while rejecting traditional business planning in favor of direct market validation. The event concludes with Sorey's advocacy for immigrant entrepreneurs to pursue their dreams through hard work and a "pay it forward" mentality, underscored by the release of her new book *Raising Brows*.

  10. All-In Podcast32 min

    Satya Nadella on AI’s Business Revolution: What Happens to SaaS, OpenAI, and Microsoft?

    Satya Nadella, Jason, Sacks

    Satya Nadella outlined Microsoft's strategic pivot toward "manager of infinite minds" AI agents and autonomous workflows that shift the organization from specialized roles to full-stack builders, enabling a four-year period of doubled income without headcount growth. By prioritizing ecosystem effects over single-model dominance, the company is deploying Agent 365 and local Phi models to establish a global, open architecture where value accrues from orchestration rather than proprietary weights. This approach aims to drive 80% US market share in five years while facilitating worldwide economic growth through technology diffusion to the global south.

  11. Milken Institute6 min

    LeadersLink Michelle Stewart

    Michelle Stewart

    Founded by Avner Namani and Caroline Kelly, Pankind Pancreatic Cancer Australia aims to triple the five-year survival rate to 39% by 2030 through evidence-based research and patient navigation systems that address treatment inaccessibility. The organization mitigates the dangers of unproven overseas therapies by deploying clinical nurse specialists and partnering with Trial Screen to simplify complex clinical trial enrollment for diverse and rural populations. With strategic support from the LeadersLink capstone program and input from CEO Michelle Stewart, Pankind is refining this framework to accelerate therapeutic adoption and transform terminal diagnoses into manageable chronic conditions.

  12. a16z1h 10m

    The AI Opportunity that goes beyond Models

    Alex Rampell, Jen Kha, David Haber, Anish Acharya, Ari, Nick Kopp, Seema, Mark Andrusco, Joe Schmidt, Olivia, Kimberly, Gabe, Brian, Andy, Ben

    The current AI era, driven by global smartphone adoption and the 2017 Transformer breakthrough, is enabling software companies to generate $100 million in revenue within two years while displacing human labor through specialized applications. Forward-thinking firms capitalize on this shift by establishing proprietary data moats and evolving from per-seat pricing models to outcome-based strategies that solve specific "labor replacement" needs. Concurrently, investors like Andreessen horowitz are prioritizing high-conviction deals in vertical roll-ups and "AI-native" ecosystems to secure defensible systems of record rather than temporary feature differentiation.

  13. Milken Institute22 min

    A Conversation with Altérra CEO His Excellency Majid Al Suwaidi | Middle East & Africa Summit 2025

    Majid Al Suwaidi, His Excellency Majid Al Suwaidi, Joseph McMonigle

    Established as the world's largest climate-focused private fund, Altera has committed an initial $6.5 billion deployment to mobilize $250 billion in capital for the Global South alongside strategic partners Brookfield, TPG, and BlackRock. This initiative follows the landmark COP28 conference, which shifted climate diplomacy to a pragmatic, private-sector-integrated model under the political leadership of UAE officials. Fund Director Majid Al-Sawadi now leverages his diplomatic background to accelerate clean energy infrastructure, specifically targeting the energy demands of AI and industrial decarbonization in emerging markets.

  14. All-In Podcast1h 30m

    Supercharging a New FDA: Marty Makary on Science, Power & Patients

    Marty Makary, Friedberg, Chamath, Jason, Dave

    FDA Commissioner Marty McCary has implemented 42 major reforms within his first 10 months to accelerate drug approvals, reduce clinical trial timelines, and restore public trust by ending paternalistic mandates. The agency is reshaping its workforce, shifting research priorities toward environmental and microbiome factors, and challenging China's biotech dominance by streamlining U.S. regulatory infrastructure and adopting AI-driven decision tools. These aggressive changes include converting pivotal trial requirements, eliminating unnecessary animal studies, and reforming food and vaccine policies to lower costs and address chronic disease roots.

  15. Goldman Sachs23 min

    Goldman Sachs Exchanges: Outlook 2026 | Episode 2: Regional Perspectives

    David Mericle, Andrew Tilton, Jari Stehn, Alison Nathan

    Goldman Sachs economists David Miracle, Andrew Tilton, and Yari Stein outline regional economic forecasts for 2026, projecting 2.5% US growth driven by tax cuts and Fed rate reductions alongside a resilient 4.8% expansion in China fueled by manufacturing competitiveness. The analysis highlights contrasting monetary trajectories, including the Bank of Japan's aggressive tightening to 0.75% and the ECB's projected rate hold, while warning of US labor market uncertainties and European structural weaknesses. These insights, recorded on January 7, 2026, serve as the second installment of the Outlook 2026 series, setting the stage for subsequent asset class discussions.