Latest Interviews

Better Together: Humanity + Machine Learning

Frank Chen, Peter van de Ven

Tanya Cushman challenges the narrative of existential AI risk by presenting evidence that thoughtful machine learning deployment will augment human capabilities across industries, citing examples ranging from Amazon's increased hiring to autonomous medical diagnostics. Highlighting a global surge in investment from entities like Accenture and China's 2030 national goals, the presentation details how AI automates dangerous and routine tasks while fostering new roles centered on creativity and empathy. Cushman concludes by urging organizations to prioritize data integrity and open-source collaboration to ensure these technological shifts strengthen society rather than trigger an arms race.

What's Next for Education Startups in 2019 (Part II)

Connie Chan, Frank Chen

This analysis projects the Chinese adult lifelong learning market to reach $70 billion by 2020, driven by mobile-first technologies and artificial intelligence that enable high-margin remote instruction for the 26–35 demographic. While Asian platforms successfully monetize continuous self-improvement, US EdTech firms face cultural spending habits that concentrate education costs in higher education rather than adulthood, prompting a strategic shift toward bundled mobile offerings and diversified revenue models. Andreessen Horowitz identifies this disparity as a key investment opportunity, advocating for mobile-native applications that leverage AI to normalize bite-sized skill acquisition across diverse personal and professional domains.

What Shutting Down Your Startup Feels Like - Avni Patel Thompson of Poppy with Kat Manalac

Avni Patel Thompson, Kat Manalac, Craig Cannon, Kat Manialek

Avni Patel-Thompson, the former CEO of the childcare startup Poppy, closed the Seattle-based company in December after three and a half years due to unsustainability in its marketplace economics and a capital runway of only six to eight months. Despite raising over $2 million and validating a unique supply of caregivers, the venture could not overcome the high-margin challenges of scaling from a neighborhood pilot to a larger operation without significant pivot or acquisition. Patel-Thompson executed a transparent wind-down to preserve team morale and investor relationships, describing the shutdown as the successful completion of a hypothesis rather than a personal failure while she transitions to unstructured exploration before her next venture.

Money Never Sleeps: Global Investment Outlook

Steve Krouskos, David Bonderman, Michael Carmen, Brian Sheth

Panelists in this investment forum assert that technology-driven productivity gains and the digitalization of industries significantly outweigh current geopolitical risks, citing a 700% ROI for software and a critical shortage of IT talent. The discussion highlights a structural shift where companies remain private longer due to regulatory burdens, while private capital increasingly fills credit gaps for high-growth software firms. Looking forward, experts recommend focusing on long-term AI adoption and emerging markets like India over short-term volatility, while warning of potential near-term recessions triggered by premature Federal Reserve rate hikes.

MH17: can Russia be held to account?

Following the 2014 downing of Malaysian Airlines Flight MH17 over Ukraine, a Dutch-led investigation utilized digital evidence to identify the Buk missile launch as originating from Russian-controlled territory. The Netherlands and Australia now seek international legal accountability through the European Court of Human Rights or domestic trials, aiming to prosecute specific Russian agents despite the Kremlin's denial and jurisdictional hurdles. While these proceedings face significant enforcement challenges due to the absence of extradition mechanisms, they represent the primary avenue for establishing state responsibility and asserting that the international community rejects the dismissal of the incident.

Building Funds of Tomorrow: Technology and Talent in the Future of Asset Management

David Francl, Teresa Barger, Michael DeAddio, Eddie Fishman, Taylor O'Malley

Eddie Lampert, Michael Shapiro, and Taylor W. Bellows discuss how integrating human and machine intelligence drives productivity, accelerates idea velocity, and refines alpha generation while shifting risk management and compliance to automated systems. The panel emphasizes that firms prioritize building proprietary technology only for core differentiators, opting instead to purchase mature third-party solutions for operational efficiency and to mitigate overfitting through rigorous data validation. Furthermore, the discourse highlights evolving workforce strategies, including "farm team" talent acquisition, the cultivation of diverse and values-driven cultures, and the use of behavioral analytics to monitor non-market risks across global teams.

Press Pause: Wellbeing for the Always On feat. Jay Shetty

Jay Shetty

A former monk and behavioral science expert led a practical session debunking three common mindfulness myths while demonstrating how diaphragmatic breathing enhances creativity and productivity. Through interactive challenges like multitasking tests, the instructor taught participants to redirect focus and lower their emotional response speed by synchronizing inhalation and exhalation counts. The event concluded with actionable advice to "top and tail" daily routines with brief breathing exercises, emphasizing that consistent practice requires no special equipment or settings.

Tracking Political Manipulation Through Social Media - Samantha Bradshaw

Samantha Bradshaw, Craig Cannon

A comprehensive analysis reveals that sophisticated bot networks and platform-specific algorithms have systematically amplified "junk news" and manipulated public opinion, with the United States exhibiting significantly higher disinformation ratios than other democracies. While authoritarian regimes and major platforms historically profited from unregulated engagement, emerging regulatory frameworks like Germany's NetzDG and corporate shifts toward metric transparency are attempting to curb content moderation failures and collateral censorship. Looking ahead, experts warn that social media consolidation and evolving manipulation tactics, including deepfakes in low-literacy environments, pose escalating risks for upcoming global elections, necessitating stronger digital privacy practices and algorithmic oversight to mitigate societal polarization.

Immigration Shifts 2019: Prep & Resources for Startups

Ting Ni, Hendrik Pretorius

This analysis addresses the critical recruitment and compliance challenges facing Silicon Valley employers, where foreign-born talent comprises nearly 70% of the technical workforce yet faces onboarding delays six times longer than domestic hires. The event details specific strategies for navigating high-rate Requests for Evidence in H-1B filings, leveraging alternative visa pathways like O-1 and L-1, and maintaining operations during government shutdowns. It further outlines actionable recommendations for drafting robust internal immigration policies and preparing for upcoming regulatory shifts regarding wage levels and STEM OPT extensions.

The Stories We Tell Feat. Jay Shetty

Jay Shetty

Challenging the triviality of current social media usage, the presentation outlines a strategy to leverage mobile penetration for distributing life-changing wisdom through emotionally resonant storytelling. By transforming passive consumption into active participation, campaigns by National Geographic and mental health initiatives achieved massive global reach, turning viral moments into offline community support and mentorship networks. The proposed framework prioritizes understanding audience pain, integrating entertainment to enhance retention, and enabling co-creation to facilitate implicit learning.

Putting Principle into Practice: How to Make Sustainability Profitable

Ryan Brennan, Curt Custard, Hiromichi Mizuno, John Murphy, Hugh O'Reilly, Mark Watson, Hiro Mizuno

Senior executives from major global entities including GPIF, Newton, Coca-Cola, and John Swire & Sons convened to analyze the integration of sustainability into long-term investment and corporate strategy. The panelists established a consensus that divestment is less effective than active engagement, citing empirical evidence that engaged companies generate significantly higher returns while avoiding the "rhetoric" caused by undefined standards. Key outcomes included the adoption of rigorous ESG metrics, the alignment of executive compensation with sustainability goals, and a strategic shift toward cross-sector collaboration to address complex challenges like water scarcity and decarbonization.

Working Smarter: The Future of Jobs

Richard Ditizio, Mary Gu, Robert Kelly, Dimitra Manis

This event synthesizes critical demographic shifts and technological disruptions, projecting that the global population will age significantly by 2050 while automation displaces 14% of the workforce. Speakers highlight stark disparities in educational progress between the US and Asia, alongside the rapid cost reductions in genomic sequencing and vertical farming that promise to redefine economic output. The discussion concludes with policy recommendations for gender equality and parenthood support, aiming to align future capital markets and digital fluency with a universal dream of opportunity based on merit rather than geography or origin.

The Evolution of Leadership

Heidi Toribio, Sharanjit Leyl, Marina Mahathir, Michael Owen, Igor Tulchinsky, John Wood

The Milken Women's Leadership Summit gathered industry leaders like John Wood, Marina Mahathir, and Michael Owen to redefine inclusion as active participation and highlight the fusion of data, artificial intelligence, and human resilience in modern governance. Participants addressed the critical need to democratize financial education through initiatives like WorldQuant University while navigating digital scrutiny and leveraging technology to bypass media restrictions in global advocacy. The session concluded with a consensus that future leaders must balance decisive action with long-term ecosystem building, prioritizing transparency and humility as the ultimate measures of character.

The Rise of Blockchain: How To Trust Strangers

Adam Burden, Cory Johnson, Tianmin Liu, Sopnendu Mohanty, Kaidi Ruusalepp

Moderated by Adam Burden, a panel featuring experts from Ripple, Iki Finn, Funderbeam, and the Monetary Authority of Singapore defined blockchain's shift from theoretical trust mechanisms to production use cases that cut settlement times from days to minutes. The discussion detailed specific implementations where Ripple streamlines cross-border payments, Iki Finn traces agricultural supply chains, and Singapore's Project Ubin tests tokenized currency, while highlighting that high-volume transaction integrity remains a technical hurdle. Experts concluded that while the technology offers significant efficiency gains for financial services, supply chains, and government, its widespread adoption depends on resolving regulatory friction and ensuring that governance structures can evolve alongside the code.

a16z Podcast | All About Synthetic Biology

James J. Collins, Vijay Pande, Hanne Tidnam, Hannah, Jim Collins

Emerging from a late 1990s pivot by biomedical engineers seeking to reverse-engineer biological networks, synthetic biology was formally launched in 2000 following the breakthrough construction of a genetic toggle switch by Jim Collins' lab alongside a repressilator by Michael Elowitz and Stan Leibler. The discipline has since evolved from academic skepticism into a hybrid industry balancing rational engineering design with directed evolution and machine learning, ultimately transitioning from failed bioenergy hype to a sustainable focus on high-value biomedicine, therapeutics, and educational programs like BioBits. Looking forward, the field is poised to deliver transformative applications ranging from programmable living therapeutics to environmental solutions like carbon-sequestering algae, bridging the gap between theoretical biology and practical utility over the coming decades.