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  1. Milken Institute35 min

    A Conversation with Chef José Andrés

    José Andrés, Frank

    World Central Kitchen, founded by José Andrés, deploys a decentralized network of over 44,000 volunteers to serve millions of meals globally by prioritizing immediate on-site adaptation over rigid bureaucratic planning. In crisis zones ranging from the Bahamas to Haiti, the organization utilizes local food systems and improvised logistics to deliver fresh nutrition while transitioning to economic recovery initiatives that support local micro-businesses. This model, funded primarily by small individual donations, explicitly challenges traditional aid structures by focusing on preventing health crises through nutrition rather than treating illness after the fact.

  2. Milken Institute59 min

    Age-Forward 2030: The Intersection of Housing and Health Care

    Susan Donley, Gretchen Alkema, Bechara Choucair, Tama Duffy Day, Christopher Herbert, Susan Donnelly

    Driven by the urgent reality that half of middle-income seniors cannot afford both housing and care, this event convenes policymakers, healthcare leaders, and urban planners to address the rising demographic of adults over 80 who face severe social isolation and financial insecurity. The discussion highlights successful cross-sector initiatives, such as California's "Master Plan for Aging" and intergenerational housing models, which integrate affordable housing with health services to reduce costly hospitalizations and extend life expectancy. Participants outline a 2030 vision requiring federal and local governments to dismantle policy silos, reform zoning laws, and invest $200 million or more to create stable, age-friendly communities that leverage older adults as active societal contributors.

  3. Milken Institute58 min

    Gut Feeling: Food, Microbiome, and Disease Prevention

    Julie DiBiase, Robynne Chutkan, Rob Knight, David Perlmutter, Karen Sandell Sfanos, Robin Chutkan, Mark Hyman

    Leading experts in functional medicine and microbiome research convened to establish that diet and environmental exposure fundamentally dictate human health by shaping the trillions of symbiotic microbes governing metabolism and immunity. Their discussions highlighted critical interventions, ranging from plant-rich dietary protocols that promote beneficial bacteria like *Akkermansia* to germ-free animal studies proving that specific microbial strains can transmit diseases such as cancer and autoimmune disorders. Ultimately, the panel advocates for a shift toward personalized medicine that utilizes longitudinal microbiome data and holistic lifestyle changes to prevent chronic illness rather than relying on transient pharmaceutical fixes.

  4. Milken Institute23 min

    Tuesday Lunch With Alex Azar, Secretary, US Department of Health and Human Services

    Alex Azar, Michael Milken

    Secretary Azar outlined a unified healthcare strategy centered on three core promises of affordability, choice, and quality, executing this vision through value-based payment models and targeted initiatives for high-impact areas like the opioid crisis and chronic kidney disease. Specific progress includes a 5% drop in overdose deaths and a shift to risk-sharing primary care models that empower providers to address social determinants of health, alongside efforts to expand home dialysis and stabilize ACA premiums through state reinsurance pools. The administration's "protect what works, fix what is broken" approach seeks to safeguard coverage for 331 million Americans while redesigning payment structures to prioritize preventive care and long-term fiscal sustainability.

  5. Milken Institute1h 0m

    The Business Case for Addressing Social Determinants of Health

    Joanne Kenen, Georges Benjamin, Thomas Moriarty, Ashley Perry, Lauren Shweder Biel, Emily Yu, Joanne Cannon, Lauren Schwader-Beal, Katherine Connelly, Michael Golinkoff

    Moderated by Joanne Cannon, a panel of public health leaders and corporate strategists redefined the conversation around Social Determinants of Health by prioritizing the business case for intervention over traditional philanthropy. Speakers detailed scalable models such as DC Greens' produce prescription program and CVS's integrated health hubs, which leverage data-driven insights to prove cost savings through medication compliance and reduced emergency room visits. The group concluded that sustainable growth depends on transitioning funding from grants to payer reimbursement within value-based care systems, leveraging political and corporate influence to address root causes like housing instability.

  6. Milken Institute1h 1m

    Opioid Addiction: A Crisis Fueled by Stigma

    Robert Redfield, Sarah Carlin-Smith, Dr. Kelly Clark, Gary Mendel, Dr. Andrei Ostrovsky, Jerome Adams, Ronnie Solomon, Michael Golinkoff

    A collaborative panel led by Surgeon General officials and researchers from Shatterproof and McKinsey identifies stigma as the primary barrier in the opioid crisis, highlighting how it drives public misunderstanding, provider bias, and critical gaps in Medicaid and federal funding. The group outlines a strategic shift toward humanizing recovery narratives, integrating addiction care into chronic disease management frameworks, and utilizing settlement funds for evidence-based programs to reduce overdose mortality by 50%. By advocating for the removal of restrictive privacy laws like 42 CFR Part 2 and the elimination of the X-waiver, the initiative seeks to dismantle systemic prejudices that currently prevent 60% of treatment facilities from offering FDA-approved medications.

  7. Milken Institute1h 5m

    The Future of Brain Health

    Maxine Waters, Michael Clowden, Meg Terrell, Dr. Ruth Benka, Dr. Marie Bernard, Dr. Rod Hockman, Nora Super, Dr. Rudy Tanzi

    Congresswoman Maxine Waters secured bipartisan backing from 130 legislators for a proposed $2.65 billion Alzheimer's research budget, aiming to meet the 2025 national goal of a cure while addressing the projected bankruptcy of the U.S. healthcare system. Parallel scientific advances, including Biogen's Aducanumab and new insights into viral links and sleep-based protein clearance, are being matched by systemic reforms to shift 50% of care to home settings and address the disproportionate burden on female caregivers. Despite these strides, experts emphasize that reducing reliance on acute hospitalization and mitigating risks through lifestyle interventions like blood pressure control and social engagement remain critical to curbing the disease's demographic and economic impact.

  8. Jane Street47 min

    Unboxed Types for OCaml

    Stephen

    The presentation "Making a Camel Less Like Lisp and More Like C++" addresses OCaml's performance limitations by introducing explicit "layout kinds" that allow the compiler to statically determine memory representations for unboxed types like 64-bit integers and records. This system distinguishes between tagged pointers managed by the garbage collector and raw bit representations passed directly in registers, enabling efficient libraries to remain opaque while avoiding the overhead of standard boxing. By replacing fragile dynamic heuristics with explicit type annotations, the proposal facilitates predictable high-performance computing without sacrificing the language's safety guarantees or requiring complex template expansion.

  9. a16z25 min

    How to Build an Open Source Business

    Peter Levine

    This analysis details the modern renaissance of open source investment, highlighting how exit valuations have surged from MySQL's 2008 billion-dollar acquisition to recent IPOs of firms like GitHub and MongoDB. It outlines a three-stage success framework where project community fit evolves into product and value market fit, supported by diverse monetization models such as open core and SaaS that allow founders to compete effectively against public cloud providers. The discussion further identifies critical scaling strategies, emphasizing the need to balance commercial growth with community health to avoid failure modes like perceived closed-source behavior while navigating the emerging trends of AI and blockchain in the sector.

  10. Milken Institute49 min

    Dialogue with Dato' Seri Anwar Ibrahim

    Dato' Seri Anwar Ibrahim, Dato' Seri Anwar bin Ibrahim, Haslinda Amin, Michael Milken, Curtis Chin, Anwar Ibrahim, Michael Swaito, Joe Brock

    Anwar Ibrahim and Mahathir Mohamad lead a transition government in Malaysia that prioritizes dismantling race-based economic policies, combating systemic corruption, and replacing the New Economic Policy with a need-based framework. The administration plans to recover billions from the 1MDB scandal to fund education and social services while managing a predetermined handover of the premiership from Mohamad to Ibrahim in May 2020. This strategic governance aims to redefine the nation's "Asian Dream" by fostering multiracial democracy, addressing severe poverty statistics, and positioning Malaysia as a stable economic force amid regional geopolitical tensions.

  11. Milken Institute54 min

    MENA: Building the Next FinTech Hub

    George Hay, Marcelo Giugale, Ben Lawsky, Khalid Saad, Richard Teng

    Experts from the World Bank, US regulators, and the MENA region convened to define the structural prerequisites for establishing a regional fintech hub, emphasizing the critical roles of unified regulatory frameworks, legal certainty, and indigenous talent development. The panel contrasted the fragmented US sandbox environment with Singapore's integrated model while highlighting specific MENA strategies to bypass low financial inclusion rates through government-led digital payment initiatives. Key figures from Bahrain FinTech Bay and ADGM advocated for regional cooperation and high-standard asset regulations to foster institutional trust and transform the area into a sustainable global financial technology center.

  12. Milken Institute1h 2m

    Institutional Investors: Stewarding Long-Term Assets

    Steffen Meister, Alain Carrier, Sophia Cheng, Neil Cunningham, Blake Hutcheson

    Representatives from the CPP Investment Board, OMERS, PSP, and Cathay Financial Holdings outlined aggressive strategies to expand private market allocations while targeting assets in Asia and emerging markets to capitalize on long-term growth. These institutional investors emphasized active governance and in-house talent acquisition to distinguish high-quality investments amidst valuation compression and geopolitical noise. The panelists concluded that despite fierce competition and macroeconomic headwinds, the shift of capital toward private assets remains essential for delivering sustainable returns as the public market landscape shrinks.

  13. Y Combinator5 min

    Consume Information That Encourages You To Do More - Dalton Caldwell

    Dalton Caldwell

    Founders are urged to curate their information diet by discarding content that glorifies fundraising or demands investor approval, as such media often delays product development and creates unnecessary psychological barriers. The speaker emphasizes that early-stage success relies on action-oriented thinking rather than personal branding, noting that most Y Combinator-backed companies achieved traction without a public presence in their first six years. By prioritizing sources that inspire building and serving others over those focused on valuation or thought leadership, entrepreneurs can foster a mindset conducive to genuine growth and bottom-line results.

  14. Milken Institute57 min

    Perfecting Precision Health: Personalizing Medicine for All

    Joseph Mocanu, Shiho Azuma, David Berry, Kuldeep Singh Rajput, Helmut M. Schuehsler, Edwin Morris, Helmut Schüssler

    A panel of healthcare leaders from Matic Medical Imaging, Integral Health, Ping An Good Doctor, Bioformis, and TVM Capital discussed the transition from reactive treatment to proactive, personalized medicine driven by AI and digital therapeutics. These innovators are leveraging regulatory shifts in the FDA and China to reduce drug development timelines, cut costs by up to 40%, and integrate remote primary care into national insurance frameworks. Despite challenges regarding data privacy and the economic viability of preventive care models, the collective strategy aims to replace traditional provider structures with consumer-owned health ecosystems that prevent chronic disease onset.

  15. Milken Institute54 min

    Truce or Dare: Navigating US-China Relations

    Curtis Chin, Steven Ciobo, Ng Kok Song, Weijian Shan, Lord Mandelson

    Moderated by former Australian Trade Minister Steve, a panel including Kok Song of Avanda, PAG CEO Weijin Shan, and former European Trade Commissioner Lord Peter Mendelsohn analyzed the deteriorating US-China economic relationship and the declining probability of a bilateral trade deal before the 2020 election. Participants highlighted how tariffs have widened the US trade deficit while China's shifting focus toward domestic consumption and supply chain stickiness have left American consumers bearing an estimated $80 billion in costs. The experts forecast a prolonged period of geopolitical friction and potential global system bifurcation, predicting that political posturing will likely prevent meaningful resolution despite severe economic inefficiencies.