Latest Interviews
Showing 2221–2235 of 5,336 transcripts.
Clear all filters- Goldman Sachs10 min
Biopharma opportunities and macro challenges: A check-up on the industry
Asad Haider, Chris Shibutani, Salveen Richter, Sylvain
Major pharmaceutical and biotech leaders converged to identify GLP-1 agonists and AI integration as primary drivers for a market revised upward to $130 billion, while strategically addressing patent cliffs through aggressive external collaborations and M&A targeting metabolic and neurology assets. Although the biotech IPO window has reopened with nine clinical-stage offerings, investor sentiment remains sensitive to interest rate trajectories and the need for immediate commercial validation of AI-driven discoveries. Consequently, industry capital allocation prioritizes balancing near-term revenue generators with long-term growth catalysts to navigate complex clinical challenges in the central nervous system and cardiovascular disease sectors.
- The Economist25 min
Joe of good faith: Biden bows out
Joe, Biden, Kamala Harris, Dr Ruth, Rosie Bloor, Jason Palmer, John Priddo, Leo Morani, Anne Rowe, Jerry
Following a debate performance that eroded public confidence, President Joe Biden withdrew from the 2024 race and immediately endorsed Vice President Kamala Harris, positioning her to potentially become the first female president despite her lack of a proven national election record. While political analysts warn that the public still associates Harris with Biden's approval ratings and note her previous unsuccessful primary run, the party faces a competitive field led by governors and senators before the mid-August convention. Concurrently, the administration's legacy remains precarious as the upcoming election could overshadow recent legislative victories in climate and economic recovery, leaving the Democratic strategy to pivot on whether a competent opponent can capitalize on Donald Trump's polarizing nature.
- Milken Institute58 min
Traversing Real Estate Realities | Milken Institute Global Conference 2024
Ted Seides, Jase Auby, Maggie Coleman, Joshua Morris, Tim Sloan, Joshua Weintraub
Leading institutional investors and asset managers converged to analyze a commercial real estate market defined by a dislocation between elevated interest rates and slower fundamental growth, creating distinct opportunities in data centers, single-family rentals, and distressed senior credit while navigating significant risks in oversupplied office sectors. Speakers highlighted how a generational housing shortage and a looming "wall of maturities" for $2.6 trillion in commercial loans are driving a structural shift where private non-bank lenders replace exiting regional banks to fund high-yield strategies. The panel concluded that prioritizing use-based assets with defensive demographics over traditional property classifications offers a more resilient path through the current higher-for-longer rate environment, provided investors maintain strict valuation discipline against cyclical volatility.
- Milken Institute1h 1m
The Next Wave of Immunotherapy and Cancer Treatments | Milken Institute Global Conference 2024
Marc Hurlbert, Gina Carithers, Friedrich Graf Finckenstein, Anusha Kalbasi, Connie Pfeiffer, Sunil Verma, Frederick Finckenstein, Neil Verma, Anusha Singhal
Major research organizations like the Melanoma Research Alliance and the Prostate Cancer Foundation have funded over $1 billion in studies that pioneered immune checkpoint inhibitors and novel T-cell therapies for melanoma and prostate cancer. Recent advancements include the approval of Iovance's tumor-infiltrating lymphocyte treatment for solid tumors and the development of bispecific agents that reduce manufacturing delays, though challenges regarding high costs, autoimmune side effects, and the need for broader genetic screening persist. Clinical strategies are shifting toward neoadjuvant trials and combination therapies with antibody-drug conjugates to improve patient outcomes before standard care options are exhausted.
- All-In Podcast1h 16m
Trump assassination attempt, Secret Service failure, Inside the RNC, VC liquidity problem
Trump, Chamath, Jason, Friedberg, Nick, Freeburg
Following a failed assassination attempt by Thomas Matthew Crooks that killed one attendee and injured others, the Republican National Convention solidified a coalition between MAGA populists and tech interests by selecting J.D. Vance as Donald Trump's vice-presidential running mate. The hosts analyzed the event's security failures, debated the impact of political rhetoric on the violence, and examined the administration's potential shift toward isolationist trade policies and regulatory changes regarding Big Tech. Simultaneously, the discussion highlighted significant venture capital developments, including Stripe's liquidity deal and Google's potential acquisition of Wiz, while predicting President Biden's imminent withdrawal from the race due to declining donor confidence.
- Y Combinator14 min
Tarpit Ideas: The Sequel
YC partners Dalton and Michael define "tar pit" ideas as market spaces that appear highly attractive but historically fail due to a lack of genuine technological shifts or fundamental behavioral changes. While Large Language Models have rendered some previously impossible ventures viable, founders must demonstrate concrete problem-solving capabilities rather than relying on social validation or assuming the first successful iteration is imminent. This dynamic framework warns against behavioral coordination failures and fast wealth arbitrage, urging entrepreneurs to rigorously validate ideas against historical precedents and actual user needs.
- Milken Institute1h 1m
Private Equity Delivering Value | Milken Institute Global Conference 2024
John Bowman, Chris Emanuel, Martin Escobari, Jacob Kotzubei, Collin Roche, Bridget Walsh
Driven by a surge to $22 trillion in assets and a prolonged IPO drought, the private capital sector is undergoing a structural shift from financial engineering to intensive operational transformation. Leading firms like Platinum Equity, GTCR, and GIC are deploying specialized teams to execute immediate CEO changes, leverage GenAI for due diligence, and prioritize distributions over returns, while simultaneously navigating a market bifurcation that threatens non-adaptive players. This evolving landscape forces a consolidation of the 10,000 existing general partners as asset managers adopt interventionist strategies to maximize value in a high-interest-rate environment where traditional holding periods are being redefined.
- The Economist24 min
Dicky birds: the next pandemic?
Rosie Bloor, Rebecca Jackson, Kunal Patel, Adam Roberts
Former Judge Heather Hallett's pandemic inquiry report concluded that the UK government failed the public due to critically flawed preparedness, while scientists warn that H5N1's mammalian adaptations pose a distinct pandemic risk despite ongoing mRNA vaccine trials. New historical research from Ohio State University reveals that white women in New Orleans were active participants in the slave trade, utilizing the institution to accumulate independent wealth under 19th-century legal frameworks. Concurrently, The Economist has launched "Dateline," an interactive game designed to engage news-averse readers through historical archive challenges, and Editor-in-Chief Zannie Minton-Beddoes will address the aftermath of the Gaza war in the upcoming Weekend Intelligence.
- Milken Institute1h 1m
What's Trending in MedTech? | Milken Institute Global Conference 2024
Conor Hale, Kelvin Baggett, Andrew Fish, Nada Hanafi, Ryan Lakin, Michelle Tarver
Facing a constrained 2023 investment climate, the industry is pivoting from speculative hype to value-driven innovations in women's health, AI, and genomic technologies that prioritize clear patient outcomes. Regulatory frameworks like the FDA's TAP and new real-world evidence protocols are accelerating approvals while shifting focus toward patient-integrated design and equitable access. Leaders such as Abbott and J&J are now embedding affordability and diversity into R&D, ensuring devices function as intuitive, home-based solutions that address systemic provider shortages and health inequities.
- The Economist26 min
Veep show: America meets J.D. Vance
J.D. Vance, Donald Trump, Rosie Bloor, Jason Palmer, Adam O'Neill, Kinley Salmon, Kenneth Kukie
Republican vice presidential nominee J.D. Vance delivered a populist speech emphasizing his working-class roots and isolationist economic views to differentiate himself from Donald Trump and reshape the GOP's intellectual foundation. Meanwhile, economists identify Latin America's severe trade underperformance as a result of geographical barriers, economic homogeneity, and political fragmentation that limit intra-regional commerce. Finally, Kenneth Kukie argues that classic literature such as *The Trial* and *Macbeth* provides more profound insights into leadership and organizational chaos than contemporary management manuals.
- Milken Institute1h 1m
Banks Stepping Out, Private Credit Stepping In | Milken Institute Global Conference 2024
John Bowman, Jeffrey Aronson, Marianna Fassinotti, Gregory Geiling, Peter Gleysteen, Drew McKnight
The private credit market has evolved from a niche financing tool into a $2.2 trillion "big tent" asset class, driven primarily by regulatory pressures like the Basel Endgame that force banks to offload capital requirements while retaining origination roles. This structural shift has fostered a complementary partnership model where global banks leverage private capital for risk transfer and flexibility, resulting in robust credit quality despite a temporary pause in corporate activity due to high interest rates. As the industry navigates the next economic cycle, focus is shifting toward downside protection, specialized asset management, and the emerging secondary market to address the sector's lack of full stress testing since the Global Financial Crisis.
- The Economist23 min
Food for thought: raising the world’s IQ
Jason Palmer, Rosie Bloor, Robert Guest, Shashank Joshi, Emily Steinmark
The event examines the critical impact of early-life malnutrition on cognitive development and global economics, highlighting the success of Uganda's NutriCash pilot and the potential for $12 billion in targeted investment to reverse slow progress. Concurrently, analysts assess growing geopolitical threats to the 600 undersea fiber-optic cables sustaining global telecommunications, noting state-sponsored sabotage risks from Russia and China alongside the strategic vulnerability of limited repair infrastructure. Finally, the discussion presents a breakthrough in menstrual product innovation where alginate polymers transform blood into a firm gel, marking the first significant design evolution since the 1931 applicator tampon.
- Milken Institute32 min
A Conversation with Snoop Dogg and Larry Jackson | Milken Institute Global Conference 2023
Snoop Dogg, Larry Jackson, Shirley Halperin
Co-chaired by Larry Jackson and Snoop Dogg, Gamma Distribution distinguishes itself by bridging artistic vision with enterprise execution through a proprietary financial dashboard that facilitates monthly artist payouts and rapid vinyl manufacturing. The company recently appointed Saipu Delamini and Naomi Campbell to lead its expansion in Africa and the Middle East while reporting a 5 billion monthly stream volume that generated 80% growth in its first seven weeks. Despite celebrating the sell-out of limited edition Snoop Dogg vinyls and upcoming film projects, the leadership strongly criticized YouTube Shorts for generating negligible revenue relative to stream counts, underscoring their strategic pivot toward a curated, high-value roster of 15,000 artists.
- Goldman Sachs29 min
Canva CEO Melanie Perkins on growing an idea into a multibillion-dollar design company
Canva, led by co-founders Melanie Perkins and Cliff Obrecht, has scaled to serve 165 million users and 90% of Fortune 500 companies by leveraging a bottom-up adoption strategy and its proprietary Magic Studio for AI-driven design automation. The company recently pivoted toward "wall-to-wall" enterprise deployment while maintaining profitability, a trajectory supported by its strategic acquisition of visual AI firm Collido and a dedicated trust and safety framework. Guided by a dual mission of commercial growth and social impact, Canva plans to expand its ecosystem to one billion monthly active users by donating equity and profits to eradicate extreme poverty.
- a16z1h 31m
Trump Vs. Biden: Tech Policy
Trump, Biden, Marc Andreessen, Ben Horowitz
Marc Andreessen and Ben Horowitz publicly endorse Donald Trump over Joe Biden, arguing that the current administration's hostile regulatory stance toward cryptocurrency, artificial intelligence, and venture capital threatens the future of American innovation and national security. The speakers contrast the Biden administration's restrictive executive orders and proposed unrealized capital gains taxes with Trump's platform promising to repeal these measures, defend self-custody rights, and accelerate technological competition against China. Citing the recent assassination attempt on Trump as a demonstration of the unique leadership required for this era, the venture capitalists conclude that the "little tech" ecosystem faces an existential crisis under current policies that necessitates a 180-degree strategic shift.