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  1. Milken Institute41 min

    A Conversation with Steve Ballmer

    Steve Ballmer, Michael Milken

    Steve Ballmer, a Harvard graduate who left Stanford to join Bill Gates at Microsoft, has applied his strategic leadership and data-driven philosophy to diverse sectors including technology, philanthropy, and sports. He founded USAFacts.org to provide nonpartisan government data that holds officials accountable and aims to improve economic mobility, while simultaneously revitalizing the LA Clippers with a focus on championship performance and operational transparency. Ballmer's approach consistently emphasizes the necessity of high performance, clear vision, and measurable outcomes across all his current ventures.

  2. Milken Institute40 min

    California Leading the Future of Energy

    Harry Atwater, Caroline Choi, Mark Herrema, Jane Wells

    A panel featuring leaders from Caltech, SoCal Edison, and New Light Technologies explores contrasting strategies for climate mitigation, ranging from JCAP's artificial photosynthesis research and California's push for 80% zero-carbon energy by 2030 to New Light Technologies' commercial production of methane-derived biodegradable plastics. While SoCal Edison outlines the necessity of infrastructure investment to electrify transport and buildings, New Light CEO Mark Harriman details a successful licensing model that has secured billions of pounds in plastic orders with partners like IKEA. The discussion concludes by emphasizing the critical role of chemical fuels for hard-to-electrify sectors like aviation and the urgency of converting carbon emissions into valuable market products to achieve net-negative outcomes.

  3. Milken Institute59 min

    Green Gold: California's New Cash Crop

    Joe Mathews, Hezekiah Allen, Adam Bierman, Matthew Dababneh, Cat Packer, Karan Wadhera, John McCurry Jr., David Levinson, Matthew Hendershotain Jr., David Windmueller

    California's $7 billion medical marijuana industry, which produces 16 million pounds annually, faces a critical transition as only a fraction of existing retailers and growers secure licensure amidst a persistent gray market and federal Schedule I restrictions that block banking access. While experts predict inevitable consolidation driven by high compliance costs and an equity gap affecting African American communities disproportionately, ancillary investors are simultaneously targeting technology and lifestyle sectors to mitigate federal risks. Long-term industry normalization and social equity will depend on Congress removing cannabis from Schedule I to enable interstate commerce and fully integrate the market into the mainstream economy.

  4. Milken Institute1h 14m

    Made in California: Presentations from California Grown Startups

    Dorothy Rothrock, Ian Coll McEachern, Gordon Fowler, Gabe Grifoni, Susie Harborth, Stella Kramer, Carmen Palafox, Dolly Singh, Ken Sunshine

    Leaders from Make in LA, The Glue Factory, and BioLabs San Diego convened to address critical workforce shortages in California's manufacturing and biotech sectors while analyzing the rise of hardware-enabled startups and fragmented funding landscapes. The session featured five case studies illustrating this shift, including Vector Space Systems' launch vehicle innovation, Sangenomics' personalized probiotic therapy, and Thesis Couture's engineering-driven footwear. Presenters highlighted a strategic pivot from traditional networking to resource access, emphasizing the need for specialized incubators to support solopreneurs and the convergence of software with IoT and frontier technologies.

  5. Milken Institute1h 2m

    Sustainable Solutions For a Green Future

    Tracy Gray, Tom McGrath, Nancy Pfund, Dakota Semler, Azita Yazdani, Richael Young

    Moderator Tracy Marder convened a panel featuring investment leaders Nancy Fund of DBL Partners and Tom McGrath of Vital Clean Tech Ventures to explore how impact capital drives innovation in sectors like transportation, energy storage, and agriculture. The discussion detailed specific breakthroughs from founders including Michelle of Mammoth Trading, Dakota Simler of Thor Trucks, and Azita Yazdani of Exergy Systems, who presented data-driven solutions for groundwater management, electric heavy-duty logistics, and decentralized water recovery. Ultimately, the session emphasized the necessity of long-term policy stability and equitable workforce development to scale these technologies toward the $1.3 trillion annual sustainable energy investment required by 2030.

  6. Milken Institute57 min

    Pt. 1 A Conversation with Steve Ballmer Pt. 2 California's Future Economy

    Steve Ballmer, Michael Milken, Kevin Klowden, Kevin Demoff, Charles Harrington, Paul Markovich, Betty Yee

    Former Microsoft CEO Steve Ballmer applies his "great ideas" and performance-driven leadership philosophy to his current ventures, including his 2014 acquisition of the NBA's Los Angeles Clippers and his nonpartisan USAFacts initiative. This event details Ballmer's strategic focus on winning championships, his "venture capital philanthropy" for early childhood education, and his data-driven approach to government accountability. The discussion culminates in a broader panel on California's economic future, where experts examine the threats of automation, healthcare inflation, and cybersecurity to sustainable workforce growth and public sector reform.

  7. Y Combinator1h 0m

    Building Dota Bots That Beat Pros - OpenAI's Greg Brockman, Szymon Sidor, and Sam Altman

    Greg Brockman, Szymon Sidor, Sam Altman, Craig Cannon

    Future projections suggest that hardware scaling and brain-like specialized architectures will unlock qualitatively different model behaviors, while recent evidence indicates that optimizing basic algorithms and batch sizes offers more immediate impact than developing new model structures. Concurrently, the OpenAI Dota 2 project demonstrated that robust engineering infrastructure and reinforcement learning self-play enabled bots to master the game and defeat top professionals within weeks, revealing emergent tactics such as psychological baiting. These developments highlight a field where strong distributed systems engineering and bug-free code are becoming as critical as advanced theoretical knowledge, effectively bridging the gap between complex virtual simulations and real-world AI applications.

  8. Goldman Sachs8 min

    Talks at GS – Dr. Paula Johnson: Advocating for Freedom of Speech and Diversity on Campus

    Dr. Paula Johnson, Edith

    Biomedical research highlights significant disparities in heart disease and neurologic conditions between sexes, necessitating an interdisciplinary approach that integrates sociology, economics, and epigenetics rather than treating biology in isolation. Simultaneously, experts advocate for intentional leadership and data-driven goals to dismantle silos between sex, gender, and race while promoting free speech as a shared value essential for mutual learning across differences. This dual focus calls for conditions where dialogue assumes the potential for understanding opposing viewpoints, ensuring that advancing gender equality and protecting democratic discourse proceed in tandem.

  9. Goldman Sachs13 min

    Talks at GS – Icarus: Uncovering a Scandal of Olympic Proportions

    Bryan Fogel, Dan Cogan, David Fialkow

    Director Brian Fogel launched a documentary project that evolved into a high-stakes thriller after scientists suggested anti-doping tests were easily bypassable, leading him to partner with Russian whistleblower Dr. Grigory Rodchenkov. Their collaboration produced the record-breaking film "Icarus," which exposed Russia's state-sponsored doping program and forced Rodchenkov into exile following threats from Vladimir Putin's regime. This pivotal case study demonstrates how a sports investigation transformed into a survival narrative, ultimately setting market benchmarks for documentary valuations and catalyzing the shift toward streaming platforms as the primary distributor for the genre.

  10. Y Combinator1h 2m

    Casey Neistat and Matt Hackett on Live Video's Struggle for Interestingness

    Casey Neistat, Matt Hackett, Craig Cannon

    The organization pivoted from failed raw live-streaming concepts to "Panels," a constrained product designed to foster articulate debate on daily news while employing strict moderation to mitigate online toxicity. This evolution reflects a broader hybrid strategy that merges media content creation with engineering rigor, overcoming cultural friction between newsroom and tech teams to build a sustainable "media plus product" model. Supported by CNN's long-term capital, the founders have transitioned from a survival mindset to a decade-long vision, prioritizing team stability and deep content development over immediate viral metrics.

  11. Milken Institute35 min

    A Conversation with FDA Commissioner Scott Gottlieb

    Scott Gottlieb

    Former FDA Commissioner Scott Gottlieb outlines a multifaceted regulatory strategy addressing the opioid epidemic, tobacco addiction, and the aftermath of Hurricane María on Puerto Rico's critical medical manufacturing sector. He emphasizes adapting regulatory frameworks for emerging technologies like artificial intelligence and digital health tools while prioritizing the prevention of medical misinformation and product shortages. The discussion highlights a shift toward reducing review cycles, de-risking early-stage development, and utilizing post-market surveillance to balance safety with innovation.

  12. Milken Institute1h 2m

    Women Leading a Wellness Revolution

    Joyce Chang, Nancy Brinker, Alexia Brue, Donna Karan, Melanie Whelan

    Moderated by Joyce Chang, a panel of industry leaders including Donna Karan, Nancy Brinker, Alexia Brew, and Melanie Whalen convened to redefine the wellness movement as a collaborative force driven by community accountability and shared impact. The discussion highlighted distinct strategies for systemic change, from SoulCycle's peer-driven transformation model and Well and Good's democratization of health journalism to Susan G. Komen's focus on closing care access gaps and Urban Zen's integration of holistic care within commercial and healthcare frameworks. Ultimately, the group agreed that the future of wellness relies on shifting resources from reactive "sick care" to preventative lifestyle solutions supported by clean data and scalable community networks.

  13. Milken Institute34 min

    A Conversation with PepsiCo CEO Indra Nooyi

    Indra Nooyi, Michael Milken, Andrew, Mike

    PepsiCo CEO Indra Nooyi transformed the beverage and snack giant through "Performance with Purpose," a strategy that integrated social and environmental sustainability into core operations while shifting the revenue portfolio toward healthier product lines. This cultural overhaul was driven by scientific leadership under Chief Scientific Officer Dr. Mahmood Khan and reinforced by tying executive compensation to specific nutritional and environmental goals. Nooyi further extended the company's impact by forging partnerships with healthcare institutions to improve access for underserved veterans and advocating for systemic policy changes to address chronic disease and nutritional equity.

  14. Milken Institute54 min

    A State of Emergency: Integrative Approaches to Addiction and the Opioid Epidemic

    David Beier, Jerome Adams, Terry McAuliffe, Lori McFarling, Tom Moriarty, Nora Volkow, Tammy Wincup

    A federal and state coalition deployed 14,000 officials alongside private sector partners like CVS and Discovery Education to address the opioid crisis through prevention economics, educational outreach, and prescription limits that reduced Virginia's over-prescriptions by one-third. Initiatives including a new data-sharing compact among 46 governors and the Surgeon General's social capital report aim to leverage granular prescription analytics and community resilience to cut costs associated with incarceration and unemployment. These coordinated efforts target the multifactorial nature of the epidemic by embedding science-based prevention in classrooms, enforcing seven-day prescription caps, and expanding safe disposal programs to recover from 64,000 overdose deaths recorded in 2016.

  15. Milken Institute1h 1m

    Boundless Potential: How Unlocking Big Data Can Change Health

    Dan Diamond, Murray Aitken, Aneesh Chopra, Martin J. Murphy, Robin Thurston

    Industry leaders from Quintiles IMS, Helix, and the Obama administration convened to evaluate big data's transition from hype to a tangible reality that is currently constrained by fragmented data, misaligned financial incentives, and a cultural gap in healthcare adoption. The panel highlighted Project Data Sphere, which has grown into the world's largest open-access cancer trial database to enable synthetic control arms that could halve trial timelines and improve survival rates for small cell lung cancer. Looking forward, experts discussed how lowering sequencing costs, blockchain privacy tools, and shifting toward value-based payment models aim to overcome current silos and empower consumers to drive precision public health initiatives.