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  1. Milken Institute48 min

    A Conversation with FDA Commissioner Scott Gottlieb

    Scott Gottlieb, Michael Milken, Indra Nooyi

    This summit convened experts and FDA leadership to address critical public health challenges, including the link between sleep deprivation and obesity, the scaling of screen time interventions, and the opioid epidemic. Regulatory strategies were detailed for reducing opioid exposure through shorter prescription durations, while new tobacco policies aim to minimize nicotine addiction in combustible products and regulate youth-targeted vaping technologies. Additionally, the discussion covered FDA responses to supply chain disruptions in Puerto Rico following a hurricane and the development of regulatory frameworks for emerging digital health and artificial intelligence tools.

  2. Milken Institute49 min

    The Rapidly Changing Food Industry and What it Means for Health

    Michael Klowden, Cristina Alesci, Shane Emmett, Neil Grimmer, Douglas Munk, Jonathan Neman, Irwin Simon

    Leaders from Sweetgreen, Nestlé Ventures, and emerging startups convened to address the industry's structural shift from industrial mass production to personalized, transparent nutrition driven by millennial demands. While major corporations like Nestlé deploy $900 million initiatives to incubate smaller brands and reduce sugar and sodium, panelists highlighted persistent supply chain bottlenecks and shelf-space barriers that cause 85% of new healthy food companies to fail within 24 months. The discussion concluded that achieving price parity and long-term scale requires bridging the gap between rapid consumer adoption, evidenced by 40% revenue growth in targeted health brands, and the slow, three-year organic certification timeline necessary to secure sustainable ingredient sourcing.

  3. Milken Institute1h 9m

    A State of Emergency: Integrative Approaches to Addiction and the Opioid Epidemic

    David Beier, Jerome Adams, Terry McAuliffe, Lori McFarling, Tom Moriarty, Nora Volkow, Tammy Wincup, Indra Nooyi, Scott Gottlieb

    Federal and state leaders are mobilizing a multi-sector response to the opioid crisis, deploying 14,000 officials while partnering with organizations like CVS and Discovery Education to expand prevention education and pharmaceutical take-back programs. This coordinated strategy integrates clinical data, economic recovery initiatives, and new state-level regulations, such as Virginia's prescription limits, to address the 22% surge in overdose deaths and the underlying social determinants driving addiction. Stakeholders are urged to audit medicine cabinets and commit to shared resource distribution, aiming to transition from reactive emergency measures to proactive community resilience through improved health infrastructure and data analytics.

  4. Goldman Sachs19 min

    Talks at GS – Edward Norton: Capitalism and Creative Disruption

    Edward Norton

    In a discussion spanning his activist family lineage and career in entertainment, actor Edward Norton analyzes the necessity of treating ecological services as a financial asset class to drive sustainability. He contrasts the late-1990s studio system's willingness to risk new voices, exemplified by *Fight Club*, with the modern disruption caused by streaming services that have dismantled traditional DVD revenue models. Norton further details his transition to founding EDO, a data science firm applying finance-grade ROI analytics to media to replace outdated engagement metrics and align ad spend with actual audience action.

  5. Y Combinator1h 13m

    Content Marketing Tips from Experts at First Round Capital and Andreessen Horowitz

    Camille Ricketts, Sonal Chokshi, Craig Cannon

    First Round Capital and a16z articulate a content philosophy that prioritizes strategic metrics and deep, long-form storytelling over vanity traffic, utilizing an editorial instinct honed through pattern recognition. These firms deploy a rigorous production workflow ranging from a three-tier interview framework to the use of "maker schedules" that protect creative energy while balancing reactive news with enduring "stock" projects. Their approach to audience growth relies on identifying niche "true fans" and leveraging proprietary data narratives to ensure utility, rejecting shallow advertorials in favor of authentic, emotionally resonant, or tactical advice.

  6. Milken Institute1h 38m

    A Conversation with Ray Dalio and Michael Milken

    Ray Dalio, Michael Milken

    Ray Dalio outlines his journey from a 1960s caddie to the architect of Bridgewater's "idea meritocracy," a philosophy forged after a costly 1982 sovereign debt mistake forced him to prioritize objective disagreement over ego. Drawing on historical cycles like the 1974 market crash and 1937 recession, Dalio warns of current parallels in wealth disparity and pension funding gaps while critiquing Bitcoin as a speculative bubble despite China's engineering strengths. His analysis concludes that future economic resilience depends on radical transparency, automation-ready skills, and recognizing that sustainable wealth is a byproduct of value creation rather than an end goal.

  7. Goldman Sachs23 min

    Talks at GS – Ambassador Christopher Hill: Then & Now – The North Korean Nuclear Crisis

    Christopher Hill

    North Korea has shifted from historical negotiation attempts to a strategy under Kim Jong-un that legally enshrines nuclear weapons to decouple U.S. forces from its allies while developing solid-fuel missiles capable of threatening the American mainland. Addressing this evolving threat requires a multi-pronged approach combining stringent U.S.-led sanctions, cyber operations, and renewed diplomatic efforts, all while navigating China's internal conflict between economic interests and security fears of regime collapse. Without sustained global cooperation and military reassurances for South Korea and Japan, the risk of miscalculation remains high as Pyongyang continues to advance its nuclear capabilities.

  8. Milken Institute59 min

    Japan's Renewal: The Fight to Stay Ahead

    Kotaro Tamura, Daisuke Iwase, Takumi Shibata, Keiko Tashiro

    A panel of experts analyzed how Japan is leveraging a 4% annualized growth rate and aggressive corporate governance reforms to stabilize its economy amidst heightened North Korean missile threats and strategic US-China tensions. The discussion highlighted how severe labor shortages are driving rapid automation adoption and innovative aging solutions, such as elderly care robotics and policy shifts, which are creating new investment opportunities in fintech and medical technology. Furthermore, the event detailed a tourism boom targeting 40 million visitors that is not only boosting per-capita consumption but also fostering a renewed sense of national confidence while serving as a diplomatic bridge with regional neighbors.

  9. Y Combinator49 min

    Communicate with Users, Build Something They Want - Ryan Hoover of Product Hunt

    Ryan Hoover, Craig Cannon

    Ryan Hoover secured Y Combinator investment by validating Product Hunt through manual outreach and email lists before engineering resources were committed, eventually launching the platform as a global hub for product discovery. The company is now shifting its strategy to monetize by introducing the "Ship" paid tool for creators while expanding its angel fund "Weekend Fun" to invest in remote work and voice technology. Operating a distributed team of 17 across nine time zones, Product Hunt focuses on asynchronous collaboration and strategic pivots like dropping podcast discovery to align with its core product recommendation model.

  10. Milken Institute1h 1m

    The Blockchain: It's Not All About the Money

    Staci Warden, Leanne Kemp, Greg Li, Sopnendu Mohanty, David Treat, Zia Zaman

    At a Milken Institute panel moderated by industry leaders from JPMorgan and Accenture, representatives from the Monetary Authority of Singapore and major corporations outlined how blockchain replaces fragmented databases with shared, immutable ledgers to drive regulatory experimentation and supply chain transparency. The discussion detailed concrete implementations including Singapore's domestic digital currency pilot, Georgia's national land titling migration, and Everledger's diamond provenance tracking, while addressing critical challenges such as data quality, quantum threats, and the necessity of re-architecting legacy systems. Looking forward, experts predict that within a decade, this technology will automate financial reconciliation and digitize identity and health records, fundamentally shifting the economic efficiency of global asset management and clearing settlements.

  11. Milken Institute56 min

    The Asian Phenotype: An Unmet Medical Need?

    Benjamin Seet, John Connolly, Laurent Metz, Arthur Mark Richards, Patrick Tan

    Experts highlight that distinct genetic, environmental, and anatomical factors create a unique Asian phenotype, driving divergent disease patterns such as higher cardiovascular risks at lower BMI thresholds and specific cancer profiles like biliary tract malignancies. These biological differences have spurred regulatory shifts in Asia toward homegrown standards for advanced therapies while prompting medical device and pharmaceutical companies to develop localized solutions, including smaller implants and tailored dosing regimens. The ongoing transition to personalized medicine relies on integrating granular real-world data and cultural context to address these population-specific needs effectively.

  12. Milken Institute1h 6m

    Beyond the Belt and Road Initiative: Financing Asia's Needs

    William Lee, Paul Gruenwald, Gerald Keefe, Lincoln Leong, Joachim von Amsberg, Faisal Syed

    Addressing the trillions of dollars in infrastructure financing gaps across Asia, this panel discusses the Asian Infrastructure Investment Bank's strategy to mobilize private capital through innovative project selection and cross-border connectivity. By leveraging value-capture models like MTR's rail-property approach and structured financial products such as maturity transformation, multilateral institutions aim to de-risk long-term investments for global institutional investors. The discussion concludes that shifting from bank-dominated lending to a market-based system requires robust public-private partnerships, regulatory certainty, and the allocation of specific risks to ensure sustainable economic development.

  13. Milken Institute1h 1m

    Playing the Long Game: Investing in Infrastructure

    Jonathan Woetzel, Jose Rene D. Almendras, Saadia Khairi, Ben Way, Wencai Zhang

    Amidst a projected global infrastructure funding gap of $300 billion to $400 billion annually, international development banks like the ADB and IFC are deploying structural reforms and credit enhancement tools to attract institutional capital into underserved greenfield markets. These institutions utilize mechanisms such as minimum revenue guarantees, local currency bond ratings, and first-loss provisions to mitigate regulatory and currency risks that currently deter private investment in emerging economies. By distinguishing between socially essential but financially unviable projects requiring public support and commercially viable assets suitable for private financing, the sector aims to bridge the disparity between the $1.7 trillion needed in Asia and the current $800 billion level of spending.

  14. Milken Institute57 min

    Institutional Investing: The Model for the Future

    Nobel Gulati, Mark Konyn, Hugh O'Reilly, Piau-Voon Wang, Bryan Yeo

    Industry leaders from GIC, AIA, OP Trust, and NOAA Holdings convened to address structural challenges such as low returns and data overload, proposing that strategic asset allocation and liability-driven approaches yield superior outcomes over traditional manager selection. The panel highlighted a significant shift toward insourcing capabilities, technological integration via satellite and AI, and workforce diversification to maintain agility amidst an expected market consolidation by 2037. Ultimately, participants forecast a future where homegrown Asian institutions leverage retail savings and alternative data to drive performance while ESG integration becomes a non-negotiable standard for long-term sustainability.

  15. Milken Institute37 min

    Prestige and Purpose: Asia's Luxury Market

    Ravi Thakran, Zak Brown, Naomi Campbell, Bruce Rockowitz

    Speakers including Bruce Rokovich, Naomi Campbell, and Jack Brown analyze the decade-long pivot of the Asian economy from manufacturing to wellness-driven consumption, highlighting a massive surge in fitness and premium food markets alongside the strategic revitalization of heritage brands like Kenton Kirwan. The panel identifies Singapore as a governance model and emphasizes digital engagement through motorsports and eSports as critical tools for capturing the region's youthful demographic, while noting the urgent need for greater Asian representation in global luxury fashion. Ultimately, the discussion forecasts a thirty-year dominance of the wellness sector driven by changing dietary habits and the cultural normalization of fitness across China and Southeast Asia.