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Latest Interviews

Showing 5761–5775 of 6,111 interview transcripts.

  1. Y Combinator1h 33m

    John Preskill on Quantum Computing

    John Preskill, Steven Hawking, Kip Thorne, Craig Cannon

    Established by Richard Feynman's early theoretical work, the field of quantum computing has evolved from theoretical challenges in the 1970s to a practical reality enabled by mid-1990s error correction and recent hardware advancements in superconducting and trapped-ion systems. As current devices approach 100 qubits, they are poised to disrupt public-key cryptography through Shor's algorithm while simultaneously offering transformative capabilities in quantum chemistry simulation and materials science. The industry now focuses on bridging these applications through hybrid classical-quantum systems and developing post-quantum security measures to address the imminent threat to existing encryption standards.

  2. Goldman Sachs52 min

    Katie Couric on Telling America’s Stories

    Katie Couric, David

    In a comprehensive interview, pioneering broadcaster Katie Couric details her unconventional path from a CNN failure to becoming the first solo female anchor of the CBS Evening News, where she prioritized substantive coverage of issues like sexual assault over traditional newsroom norms. She discusses her strategic negotiations for professional equality, her pivotal 2008 interview with Sarah Palin, and her current documentary series *America Inside Out*, which seeks to bridge deep societal divides through direct dialogue and the re-examination of Confederate history. Couric concludes by advocating for structural changes such as the Rooney Rule to combat workplace bias and emphasizing the critical role of proximity in fostering empathy across America's shifting demographic landscape.

  3. Goldman Sachs18 min

    U.S. Navy, Retired Admiral James Winnefeld, Jr.

    James Winnefeld, Jr., James "Sandy" Winnefeld, Jr., Gary Giglio

    Retired U.S. Navy Admiral James Winnefeld co-founded the organization SAFE following the heroin overdose death of his son, Jonathan, to address systemic failures in mental health care and pharmaceutical oversight that contributed to the nation's escalating opioid crisis. By citing CDC data that frames annual overdose fatalities as a catastrophic national security threat, Winnefeld advocates for immediate reforms including stricter prescription limits and the removal of stigma surrounding addiction treatment. The Admiral further extends this philosophy to global security, urging a complex diplomatic approach to North Korea while emphasizing that effective leadership requires holding individuals to high standards while providing essential support.

  4. Goldman Sachs20 min

    John A. Farrell: The Life, Legacy and Lessons of Richard Nixon

    John A. Farrell, Richard Nixon, Jake Seward, Jack Farrell

    Journalist Jack Farrell's biography reexamines Richard Nixon by contrasting his resilient childhood trauma and early friendship with John F. Kennedy against his calculated ambition and the fatal "Chennault Affair." The narrative details how Nixon's secret taping system and subsequent admission of Watergate involvement transformed a political scandal into an unprecedented impeachment crisis fueled by his "uncontrolled cruelty" during the final days of his presidency. Farrell ultimately frames Nixon's arc as a Shakespearean tragedy where a tragic flaw derived from his humble origins and a vow to never be out-cheated again led inevitably to his downfall.

  5. Goldman Sachs20 min

    Josh Silverman: The Future of the “Etsy Economy”

    Josh Silverman

    Amidst stock pressure and executive departures, CEO Josh Silverman restructured Etsy by consolidating operations into twenty-six high-priority initiatives while reducing the workforce by twenty percent to accelerate execution. The company abandoned fragmented metrics in favor of Gross Merchandise Sales as the sole success indicator, prioritizing immediate market expansion over short-term profitability. This turnaround strategy utilized rigorous risk management and a mission-driven culture to address growth deceleration, positioning Etsy to defend its marketplace moat against orthogonal competitors.

  6. Goldman Sachs30 min

    Chris Hughes on Founding Facebook and Fighting Inequality

    Chris Hughes, Michael Pease

    Former Facebook co-founder Chris Hughes is launching the "Fair Shot" initiative to provide $500 monthly payments to 60 million working adults earning under $50,000 annually, aiming to eradicate poverty without dismantling existing social safety nets. Funded by a 50% marginal tax rate on the targeted demographic and capital gains, this policy shifts the economic paradigm from charity to a guaranteed income floor designed to counteract the destabilizing effects of automation and income inequality. Simultaneously, Hughes leverages his history as a tech executive to advocate for strict data rights legislation and a user-owned data dividend, positioning his campaign as a dual front against both corporate monopolies and systemic poverty.

  7. Y Combinator42 min

    Mathematical Approaches to Image Processing with Carola Schönlieb

    Carola Schönlieb, Craig Cannon

    A researcher specializing in inverse imaging problems and partial differential equations is advancing techniques to reconstruct high-resolution medical, environmental, and historical data from severely limited measurements. By developing bi-level optimization strategies that integrate machine learning with interpretable, handcrafted mathematical models, this work addresses critical challenges in noise reduction and adversarial robustness for applications ranging from dynamic MRI imaging to the virtual restoration of illuminated manuscripts. The research successfully bridges theoretical stability guarantees with practical data-driven performance, enabling safer radiation exposure in CT scans and accurate 3D modeling of forest structures from airborne sensor data.

  8. Y Combinator1h 3m

    Helping Landlords Find Tenants – Sean Mitchell of Rezi

    Sean Mitchell, Craig Cannon

    Resi operates a full-risk leasing marketplace in New York and the Bay Area that transfers vacancy and tenant performance risks from landlords to itself while enabling apartment lease-ups in under ten minutes. The company funds these guaranteed upfront rent payments through a debt securitization model targeting mid-teens to 20% returns, preserving equity capital while utilizing automated underwriting to minimize discrimination. Early growth was driven by high-volume direct outreach to individual landlords, and the firm now leverages proprietary pricing algorithms to optimize unit rents ranging from $2,000 to $6,000 monthly.

  9. a16z46 min

    The Oral History of TrialPay -- Obstacles and Opportunities in Payments

    Alex Rampell, Terry Angelos

    Founded in 2006 by Alex Rampell and Terry Angelos, TrialPay pioneered offer-based payments by evolving through software, social gaming, and mobile markets before restructuring into a core ad business and a new entity called Yub in 2014. The original company eventually secured an exit through its 2018 acquisition by Visa, which integrated TrialPay's technology to expand into transactional advertising and mobile rewards. Rampell's post-mortem analysis highlighted the strategic imperative of controlling payment infrastructure, a lesson that informs current trends in verticalized commerce, payment unbundling, and programmable digital currencies.

  10. Y Combinator50 min

    Crypto Investors - Linda Xie and Avichal Garg

    Linda Xie, Avichal Garg, Craig Cannon, Avicil

    Industry experts Avicil and Linda project that blockchain adoption will initially prioritize decentralized exchanges and digital collectibles over complex distributed applications due to current scaling limitations. The discussion highlights a trajectory where underserved regions with inflationary currencies lead mainstream integration while technical development remains concentrated in traditional hubs like Silicon Valley and Berlin. To ensure long-term viability, the speakers advocate for mandatory default privacy, rigorous investor protection mechanisms, and a shift away from public token sales toward milestone-based venture funding structures.

  11. a16z27 min

    Shifting Risk Mindsets, from Tech to Bio

    Jorge Conde, Vijay Pande, Jeff Low, Jeffrey Lowe

    Bio-hybrid startups face critical challenges in translating novel technologies to traditional biological partners and avoiding the "death by a thousand pilots" trap through strategic deal structures. Founders must carefully position their platforms to capture value in high-impact areas like Phase III failure prediction while isolating asset risks via legal separation to prevent resource drain. Successful execution requires a hybrid approach to funding and partnership, where founders bridge the linguistic gap between tech and bio communities to align reimbursement models with long-term investor expectations.

  12. Goldman Sachs41 min

    Sir Richard Branson: Leading with Vision and Taking on Challenges

    Sir Richard Branson, David Solomon, John F.W. Rogers, Kevin McCarthy, Tyler Perry, Danny Meyer, Sarah Kauss, Wilbur L. Ross, Sara Blakely, Michael Bloomberg, Gina Raimondo, Rick Snyder, Marco Rubio, Lloyd Blankfein, Warren Buffett

    Richard Branson founded Virgin Group in the 1970s by launching Student magazine and Virgin Records despite operating within a state-dominated British economy, eventually pivoting from retail and aviation to space exploration and sustainable energy. Under his leadership, the conglomerate expanded into major ventures like Virgin Atlantic, Virgin Galactic, and Virgin Orbit while simultaneously addressing global challenges through Virgin Unite and geothermal initiatives in the Caribbean. Branson's strategy combines aggressive risk mitigation, such as lease clauses for aircraft returns, with a people-centric corporate culture that prioritizes employee well-being and entrepreneurial problem-solving.

  13. Goldman Sachs29 min

    A Conversation with Lloyd Blankfein

    Lloyd Blankfein, Dr. Gail Mellow, John F.W. Rogers, Rep. Kevin McCarthy, Tyler Perry, Danny Meyer, Sarah Kauss, The Honorable Wilbur L. Ross, Sara Blakely, Michael Bloomberg, Gov. Gina Raimondo, Gov. Rick Snyder, Senator Marco Rubio, Sir Richard Branson, Warren Buffett

    Goldman Sachs CEO Lloyd Blankfein discussed the "10,000 Small Businesses" initiative, a partnership with LaGuardia Community College that has assisted 6,700 entrepreneurs by combining community accessibility with institutional resources. Drawing on his own journey from public housing to the firm's top leadership, Blankfein outlined key strategies for business resilience, emphasizing the need for talent acquisition, capital access, and active political engagement to overcome regulatory hurdles. He concluded by advising business owners to separate personal crises from professional duties while noting that current economic conditions require a careful balancing act by the Federal Reserve to avoid aggressive rate hikes.

  14. Goldman Sachs7 min

    Sara Blakely: Fireside Chat

    Sara Blakely, Kathy Elsesser, John F.W. Rogers, Kevin McCarthy, Tyler Perry, Danny Meyer, Sarah Kauss, Wilbur L. Ross, Michael Bloomberg, Gina Raimondo, Rick Snyder, Marco Rubio, Lloyd Blankfein, Richard Branson, Warren Buffett

    Sarah Blakley founded Spanx with $5,000 to solve the issue of visible panty lines for women wearing white pants, despite lacking formal business training or industry connections. After facing initial skepticism from manufacturers, she leveraged a childhood culture that rewarded failure to build a company culture centered on public error disclosure and challenging industry norms. Her strategy of deviating from standard practices enabled the creation of a footless pantyhose product that revolutionized the hosiery market and generated significant breakthroughs.

  15. Goldman Sachs56 min

    Sarah Kauss: Starting Up and Going Global

    Sarah Kauss, Jo Natauri, John F.W. Rogers, Kevin McCarthy, Tyler Perry, Danny Meyer, Wilbur L. Ross, Sara Blakely, Michael Bloomberg, Gina Raimondo, Rick Snyder, Marco Rubio, Lloyd Blankfein, Richard Branson, Warren Buffett

    After gaining experience as a CPA during the dot-com era, Sarah Kaus founded Swell to combine fashion-forward hydration with a mission to reduce plastic waste. Under her leadership, the company expanded from a single boutique concept into a global brand stocked in 2,200 U.S. stores and major partners like Starbucks and Target. Kaus now guides a 100-person team with a philosophy that prioritizes financial self-sufficiency, rigorous quality control, and a culture that blends aggressive scaling with core environmental values.