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  1. Milken Institute1h 1m

    Where Is the Next Cure? | Global Conference 2024

    Alice Park, Noubar Afeyan, Aloe Blacc, Daphne Koller, Samarth Kulkarni, Pablo Legorreta

    Leading biotech executives and researchers are redefining the industry by shifting from chronic small-molecule management to precise, curative systems-based therapies like CRISPR and mRNA platforms. This transition, fueled by artificial intelligence and a "reverse translation" innovation model, has accelerated clinical timelines while projecting a $100 billion market for GLP-1 drugs and new organ-editing solutions. Despite regulatory hurdles and high initial costs for treatments like sickle cell gene editing, stakeholders anticipate that maturing technologies and scalable manufacturing will eventually democratize access to these transformative medical breakthroughs.

  2. Milken Institute1h 1m

    Rewriting the Rules of Global Conservation | Global Conference 2024

    Justin Worland, Eron Bloomgarden, Iván Duque Márquez, Jennifer Morris, Wendy Schmidt

    The event convenes global leaders and financial experts to address the crisis of 70% global wildlife decline by examining the "30x30" pledge to protect land and oceans by 2030, highlighted by Colombia's successful expansion of protected areas. Through analysis of market mechanisms like carbon pricing, debt-for-nature swaps, and the LEAF Coalition, the discussion outlines strategies to mobilize the trillions of dollars required to transition from extraction to regenerative economic models. The proceedings emphasize that achieving these targets depends on integrating indigenous land rights, deploying technology for transparent data, and aligning political will with private capital to prevent the Amazon from reaching a critical tipping point.

  3. All-In Podcast1h 46m

    The Stablecoin Future, Milei's Memecoin, DOGE for the DoD, Grok 3, Why Stripe Stays Private

    Milei, Patrick Collison, Jamie Dimon, Trump, Elon, Jason Calacanis, David Friedberg

    Stripe leaders Patrick and John Collison, joined by Chamath Palihapitiya and Dave Sacks, discussed the company's $1 trillion annual processing volume, its strategic pivot into stablecoin infrastructure via the Bridge acquisition, and its continued decision to remain private to prioritize long-term compounding. The panel also critiqued recent political missteps, such as Javier Milei's meme coin failure, while highlighting the ARC Institute's release of the Evo 2 biological AI model and Elon Musk's rapid Grok 3 training via the "Colossus" data center initiative. Finally, the conversation addressed shifting geopolitical defense strategies, the ongoing risks of asteroid 2024 YR4, and the broader impact of remote work policies on early-career professional development.

  4. Milken Institute53 min

    Africa's Youth is Using Technology to Solve Africa's Most Pressing Problems | Global Conference 2024

    Dan Keeler, Ramadan Ameen, Maya Horgan Famodu, Yolanda Mabuto, Walter Pacheco, Fred Swaniker

    A panel of industry leaders and investors analyzed Africa's transformative potential, driven by a young, mobile-connected population and surging venture capital flows that have facilitated significant fintech exits and the scaling of global talent pipelines. Discussions highlighted strategic shifts toward execution over intellectual property protection, the democratization of capital through digital asset tokenization, and the deployment of AI and drone technology to revolutionize healthcare infrastructure in nations like Rwanda. Experts concluded that bridging the skills gap through grassroots technical education and exporting digital labor are critical to unlocking economic sovereignty and ensuring sustainable growth for the continent's projected workforce.

  5. Milken Institute1h 0m

    Powering the Future: Energy Storage, Delivery, and a Modern Grid | Global Conference 2024

    Gregory Zuckerman, Donnel Baird, Nardos Bekele-Thomas, Pedro Pizarro, Andrew Ponec, Karen Wayland

    A pivotal panel discussion highlighted the accelerating global transition toward a modernized power grid driven by surging demand from AI, manufacturing repatriation, and electrification. Key figures outlined massive investment requirements, including a $370 billion California requirement and a $1.3 trillion need for African energy modernization, alongside technological shifts toward thermal batteries, extended nuclear lifespans, and SMRs. Experts concluded that overcoming regulatory bottlenecks and reforming market rules are essential to aligning infrastructure development with the urgent goals of decarbonization and grid resilience.

  6. Goldman Sachs26 min

    Macro questions and market strength

    Jan Hatzius, Dominic Wilson, Alison Nathan

    Goldman Sachs economists Jan Hatzias and Dominic Wilson project that 2025 U.S. real GDP will grow by approximately 2.5% despite an effective tariff increase of 4–7 percentage points, a scenario where tailwinds continue to outweigh policy headwinds. While the Federal Reserve is anticipated to cut rates later in the year due to sticky but manageable inflation, markets remain resilient near record highs driven by strong consumer income growth and a pricing dynamic that favors offshore equities. The analysts warn that aggressive tariff implementation poses a significant tail risk for growth and bond yields, yet they maintain that the current low recession probability supports a gradual upward drift in risk assets.

  7. The Economist14 min

    AI bosses on what keeps them up at night

    Demis Hassabis, Dario Amodei, Zanny Minton Beddoes

    Anthropic CEO Dario Amodei and DeepMind CEO Demis Hassabis offer diverging timelines for Artificial General Intelligence, with Amodei predicting arrival by 2026–2027 and Hassabis estimating a 50% probability only by 2030. Both leaders warn of severe geopolitical risks from authoritarian dominance and catastrophic safety failures, advocating for an international "CERN for AGI" framework and new global institutions akin to the IAEA to manage the technology. While Amodei emphasizes the danger of a self-improving threshold moment and the potential for lab-tested autonomous agents to cause immediate harm, Hassabis highlights regulatory imbalances and the medium-term potential for AI to solve major scientific challenges like curing diseases.

  8. Milken Institute1h 0m

    Bold Proposals for Protecting the Free-Enterprise System while Closing the Wealth Gap | GC 2024

    Michael Milken, John Hope Bryant, Brad Gerstner, Teresa Ghilarducci

    At a May 2024 Milken Institute panel moderated by Michael Milken, experts including Stephen Mnuchin, Brad, John Hope Bryant, and Theresa outlined a consensus strategy to protect the free enterprise system by replacing wealth taxes with universal financial literacy and private capital access. The discussion detailed specific legislative and corporate initiatives such as the Retirement Savings for American Act and the "Invest America" proposal, which aim to automatically enroll millions of workers in retirement accounts and establish seed accounts for newborns to counteract economic inequality. Proponents argue these structural reforms, alongside private equity expansion, are essential to prevent national decline and ensure that the impending intergenerational wealth transfer builds lasting capital rather than dependency.

  9. All-In Podcast1h 37m

    DOGE vs USAID, Crypto Framework, Google's $75B AI Spend, US Sovereign Wealth Fund, GLP-1s

    Antonio Gracias, Sacks, Chamath, Friedberg, Jason Calacanis

    David Sacks and Antonio Gracias lead the Department of Government Efficiency in auditing USAID for potential fraud and waste while simultaneously pushing for a US Sovereign Wealth Fund to monetize government assets like TikTok stakes and federal land to reduce the national debt. The administration further advances a crypto regulatory framework prioritizing stablecoin legislation and proposes a tax plan eliminating levies on tips, overtime, and Social Security benefits for seniors. Amidst these policy shifts, market participants analyze Google's record-breaking earnings and $75 billion AI infrastructure investment, while medical experts review new VA data suggesting GLP-1 drugs offer significant cardiovascular and neurological benefits beyond weight loss.

  10. Milken Institute58 min

    Innovators Rethinking Criminal Justice Systems | Global Conference 2024

    Zack Carpenter, Baz Dreisinger, Hilton Freund, Jessica Hicklin, Teresa Hodge, Ari Melber, Alex Spiro

    Global and domestic speakers including Jessica Hicklin, Theresa Hodge, and Dr. Baz convened to address the $250 billion U.S. criminal justice crisis and its disproportionate impact on racial minorities and the 50% rise in female incarceration worldwide. These innovators argued that data-driven reforms, such as implementing earned-time credits and sport-based skill building, could prevent 350,000 years of unnecessary incarceration while addressing a projected 22 million worker shortage in the energy sector. Despite significant barriers like funding mismatches and political volatility, the event emphasized shifting from "second chances" to "first chances" to leverage the 95% of released prisoners who will integrate into the workforce.

  11. Milken Institute1h 2m

    Storytelling for Change: Creating Hope out of Crisis | Global Conference 2024

    Jimmie Briggs, Andrea Bruce, Scott Harrison, Yunghi Kim, Eli Reed, Yoongi Kim

    Prominent photojournalists and social entrepreneurs Yoongi Kim, Scott Harrison, Andrea Bruce, and Eli Reed examined how visual storytelling confronts modern challenges like AI-generated disinformation and funding crises while driving tangible policy and humanitarian outcomes. The panelists detailed specific successes, including Kim's policy-altering documentation of Comfort Women, Charity Water's billion-dollar mobilization through immersive narratives, and Bruce's locally focused publication that achieved near-universal community engagement. Unifying under the belief that ethical, human-centered reporting is essential for democracy, the group emphasized the critical need for sustained public investment in original journalism to preserve truth and foster empathy across a noisy digital landscape.

  12. Goldman Sachs35 min

    How the Florida Panthers won the Stanley Cup with CEO Matt Caldwell

    Matt Caldwell, John Waldron

    CEO Matt Caldwell spearheaded the Florida Panthers' transformation from a financially struggling franchise into a Stanley Cup champion by implementing Wall Street-level financial rigor and a data-driven "grit" culture. The organization achieved this turnaround by pivoting revenue streams from traditional cable models to direct-to-consumer and Over-the-Air broadcasting while aggressively cultivating community engagement through veteran-focused initiatives and grassroots youth programs. This strategic shift not only secured the team's first championship in thirty years but also established a sustainable business model capable of thriving despite the NHL's unique salary cap constraints and the rapid evolution of sports media distribution.

  13. Milken Institute1h 1m

    Climate Outcomes 2035: New Pathways to Accelerate Capital Deployment | Global Conference 2024

    Dan Carol, Mark Gallogly, Amber D. Miller, Hiromichi Mizuno, Helen Mountford, Adam Wang-Levine

    A recent analysis reveals that while global climate policies currently project 2.7°C of warming, rapid advancements in renewable adoption and Amazon deforestation reductions highlight a stark paradox between accelerating clean energy deployment and sustained fossil fuel demand. Despite $2.5 trillion in annual investment gaps and systemic barriers like biased credit ratings and educational deficits, strategic interventions such as the US Inflation Reduction Act and new G20 finance frameworks aim to mobilize private capital through public-private partnerships and de-risked guarantee platforms. These structural shifts seek to redirect trillions toward nature-based solutions and Global South projects, addressing the critical disconnect between current financing flows and the emissions reductions required to limit temperature rise to 1.5°C.

  14. Milken Institute1h 1m

    Digital Media and Youth Mental Health | Global Conference 2024

    Jacob Ward, Kenneth Cole, Bill Ready, Jennifer Siebel Newsom, Ashwin Vasan, Sherrie Westin

    Experts and tech leaders are calling for federal regulation to address the digital toxin threatening adolescent mental health, noting that current industry incentives favor engagement over safety while parents struggle to act as the sole bulwark against online harm. With significant data linking increased screen time to rising anxiety and depression, proposed solutions include the Kids Online Safety Act, California's Age-Appropriate Design Code, and voluntary industry pledges like Pinterest's safety-first model that prioritizes well-being metrics over engagement. Although business leaders acknowledge the necessity of a regulatory floor to align financial interests with public health, the consensus remains that structural safeguards must be established to protect the developing brains of children before self-regulation or bans alone can solve the crisis.

  15. Milken Institute1h 4m

    2024: What Matters Most in Marketing | Global Conference 2024

    Michelle Stevenson, Kathy Baird, Joe Gagliese, Ella Kieran, Kenny Mitchell, Raja Rajamannar, Amy Tunick

    Key industry leaders from The Washington Post, MasterCard, and WPP emphasized that traditional brand loyalty is largely a myth, necessitating a shift toward daily earned trust and "stickiness" through consistent performance and immersive experiences. Concurrently, the convergence of the creator economy, sustainability mandates, and the historic 2024 election cycle has compelled brands to abandon polished advertising in favor of authentic, low-cost content and behavioral change initiatives that prioritize human connection over intellectual cleverness. As audiences fragment across platforms like TikTok and cinema, organizations like Levi's and National Cinemedia are adapting by co-authoring narratives with consumers and leveraging non-partisan spaces to navigate a volatile information landscape while integrating AI as a co-pilot for strategic analysis.