Latest Interviews
Showing 931–945 of 5,336 transcripts.
Clear all filters- RAISE Summit19 min
A Fireside Chat: Beyond Asimov's Laws: How GenesisAI is Bringing AI to the Physical World
Omar, Sebastien Detranier, Francois Beaufort, Theo Varontas
Genesis AI is a Paris-San Francisco startup backed by Eclipse, BP France, and Alvin that aims to automate 50% of the global economy's physical tasks by applying internet-scale foundation models to general-purpose robotics. Co-founder Sebastien Degraffe leverages a proprietary physics engine and a three-pronged data strategy to solve the scarcity of diverse robotics training data, differentiating the firm from competitors reliant on expensive human-in-the-loop collection methods. With a seed round exceeding $100 million, the company plans to deploy Proof of Concepts in pharmaceutical labs and hotels within the next year while targeting full-scale commercialization of adaptable, generalist machines over a three-to-five-year timeline.
- RAISE Summit22 min
WEKA, Cohere, Nebius: Rewriting the Rules Agentic AI and the Race to Scale
Lauren Vaccarello, Cécile Robert-Michon, Dan Shtan, VYACHESLAV TYKHONOVSKYI, DAN GALPIN, Danila
At a panel on AI infrastructure and economics, Weka CMO Lauren Vaccarello, Cohere's Cécile Robert-Michon, and Nabeus CTO Dan Galpin discussed the necessity of rethinking legacy systems to support massive scale and agentic AI. The speakers emphasized that modern requirements prioritize intelligence per token over raw cost efficiency, citing Nabeus's software-first approach that achieves near-NVIDIA benchmark performance without virtualization and Cohere's converged storage solutions that deliver 20x faster checkpointing. They concluded that enterprises must abandon rigid long-term planning in favor of short-cycle agility to navigate the rapidly shifting demands of privacy, security, and compute resources in a commercial AI landscape.
- Milken Institute36 min
Influence to Shape Platforms for Good | Asia Summit 2025
Ross Butler, Bhumi Pednekar, Curtis S. Chin
Actors Bhumi Pednekar and Ross Butler discuss their respective careers of dismantling stereotypes in Indian and Hollywood cinema while highlighting the societal pressures to pursue traditional professions over creative arts. Beyond entertainment, both advocates emphasize the transformative power of social media for disaster relief and mental health awareness, with Pednekar leading UNDP climate initiatives and Butler championing cross-cultural co-productions in Southeast Asia. Looking forward, the duo plans to collaborate on a project bridging Indian and Asian narratives while mentoring emerging talent to redefine regional storytelling globally.
- Goldman Sachs44 min
Memorial Sloan Kettering Cancer Center’s CEO on the Future of Cancer Treatment
Selwyn M. Vickers, Brian Robinson, Dr. Selwyn Vickers
Memorial Sloan Kettering leverages its vast biobank and dual expertise in computational oncology to drive a "golden era" of cancer treatment, where AI-driven predictive models and breakthroughs in immunotherapy have transformed survival rates for aggressive malignancies. Concurrently, the institution confronts rising youth cancer incidence and systemic health inequities by developing accessible genetic screening tools and deploying low-infrastructure immunotherapy protocols globally. These clinical and technological advances are grounded in a leadership philosophy that prioritizes professional excellence to dismantle socioeconomic barriers and improve care access for underserved populations.
- a16z56 min
Opendoor CEO: Building the Amazon for Homes
Kaz Nejatian, Alex Rampell, Erik Torenberg
CEO Kaz Nejatian is steering Opendoor away from its failed inventory-heavy iBuyer model toward a software marketplace aiming to control 10% of housing supply to disrupt traditional agent monopolies through 1% commissions. Following a strategic pivot triggered by the "triple whammy" of Zillow's competition, rising interest rates, and capital pullback, the company now operates in every U.S. market with features like Dallas' seven-day return window to build high-frequency demand. The ultimate vision is to internalize the entire real estate transaction chain by bundling financing and insurance, thereby reducing friction and delivering net value to consumers while avoiding the pitfalls of operating as a low-frequency asset-holding business.
- Y Combinator41 min
Ask These Questions Before Starting An AI Startup
Founder and alignment researcher Sam Altman warns that the imminent arrival of AGI within two to three years forces startups to radically rethink hiring, product design, and long-term strategy beyond traditional focus models. He argues that enterprises will soon bypass external SaaS providers by building internal software with AI, while consumer markets may shift from static apps to on-demand, AI-generated solutions that require new trust mechanisms like automated auditing. Ultimately, Altman urges founders to prioritize solving hard infrastructure problems and societal impact over immediate monetization, as the window to build defensible moats against commoditization and centralized control narrows rapidly.
- The Economist9 min
How Donald Trump made the Gaza talks happen
Donald Trump, Jason Palmer, Anshel Pfeffer
Amid unprecedented war fatigue, the Trump administration has deployed a high-level delegation led by Steve Witkoff and Jared Kushner to Sharm El Sheikh to drive an immediate ceasefire between Israel and Hamas. The proposed Phase 1 plan mandates a full halt to hostilities, a partial Israeli withdrawal, and a reciprocal exchange of 48 Israeli hostages for nearly 2,000 Palestinian prisoners to prevent famine and release military reservists. While long-term governance details regarding disarmament and international security forces remain deferred, the U.S. is aggressively enforcing this framework to bypass previous diplomatic failures and secure a permanent end to the conflict.
- Milken Institute42 min
Who Will Win the Scramble for Global Talent? | Asia Summit 2025
Tiffany Ang, David Ha, Ichiro Miyoshi, Manjit Singh, Anupam Trehan
Industry leaders from Sun Life, Cisco, Sakana AI, and Manunouchi Innovation Partners convened to address the convergence of multi-generational workforces and AI-driven disruption in the global talent landscape. Panelists detailed strategic responses to U.S. visa fee hikes and the "war for talent," ranging from Cisco's rotational career pathways to Sakana AI's equity-based compensation for international AI researchers targeting Japan. The discussion highlighted that success in this evolving environment requires balancing deep technical skills with human-centric values, such as organizational purpose and collaborative workflows, to retain Gen Z talent and navigate shifting economic ecosystems.
- All-In Podcast12 min
The Next Bubble Is Already Here - Chamath Palihapitiya
Chamath Palihapitiya, Jason, Friedberg, Nick
Speakers warn that the private equity sector, having grown to $5 trillion through artificial borrowing, faces a structural collapse driven by mismanagement and stagnant distributions as capital migrates toward a new bubble in private credit. To address the dysfunction of traditional IPOs and flawed SPAC structures, the Raptor 2 initiative has secured backing from 98.7% of blue-chip institutional investors to introduce a transparent, performance-aligned model for high-growth companies. Future iterations, Raptor 3, propose a "pre-baked IPO" using pure common stock to eliminate conversion risk and ensure fair pricing for public shareholders.
- a16z1h 3m
The Lawyerly Society vs. The Engineering State: Who Owns the Future?
Dan Filgate frames the U.S.-China competition not as a race with a definitive winner, but as a complex synthesis where American strengths in wealth creation and intellectual property must balance against China's engineering-driven capacity for infrastructure and manufacturing. The analysis highlights critical frictions between the U.S. "lawyer culture," which often paralyzes industrial progress through legal hurdles, and China's ability to enforce large-scale goals despite systemic human rights concerns and IP vulnerabilities. Ultimately, the dialogue urges the United States to avoid complacency by adopting more functional industrial policies that prioritize physical production and logistical efficiency rather than rigid legalistic processes.
CEOs of Epirus & Galvanick on the Future of Defense & Cybersecurity
Andy Lowery, Joshua Steinman, Molly O'Shea
Epirus and Galvanic founder Joshua Steinman outline a strategic pivot toward countering autonomous drone swarms and industrial cyberattacks by leveraging U.S. dominance in phased array and gallium nitride technologies. Epirus is deploying second-generation Force Field Generators ready for Army testing, while Galvanic deploys AI-driven software to protect critical operational technology infrastructure from pre-positioned state-sponsored malware. Together, these initiatives address a national security imperative by reindustrializing domestic supply chains for high-powered components and automating the detection of physical threats that traditional IT security measures cannot stop.
Joby, Dirac & Allen Control: The Future of Air, AI Factories & Defense Tech
Molly O'Shea, Eric Allison, Filip Aronshtein, Steve Simoni
The Reindustrialize 2024 summit in Detroit highlighted strategic capital infusions and operational expansions by key players such as Joby Aviation, Dirac, and Allen Control Systems to address critical gaps in the American industrial base. Joby Aviation secured further funding and strategic partnerships to advance its FAA-certified eVTOL air taxi program, while Dirac deployed AI-driven software to automate manufacturing instructions and preserve tribal knowledge, and Allen Control Systems raised capital to scale its "Bullfrog" kinetic defense turret for drone warfare. Collectively, these developments reflect a broader industry urgency to reverse offshoring trends, reintegrate vertically controlled supply chains, and deploy domestic manufacturing solutions amidst evolving geopolitical and technological pressures.
- The Economist11 min
Has Mars revealed a new clue about life on its surface?
Dr Katie Stack Morgan, Alok Jha
NASA's Perseverance rover recently identified distinct mineral patterns in Mars' "Chiava Falls" outcrop that the science team voted to classify as potential biosignatures, marking the closest any agency has come to detecting ancient life. While these findings strongly suggest a biological origin due to their specific chemical arrangement, the rover's limitations require the samples to be returned to Earth for definitive analysis. This critical next step relies on the Mars Sample Return program, which currently faces budgetary uncertainty even as scientists describe the discovery as a historic scientific milestone.
- All-In Podcast1h 30m
Biggest LBO Ever, SPAC 2.0, Open Source AI Models, State AI Regulation Frenzy
Friedberg, Jason Calacanis, Chamath Palihapitiya, David Sacks
Electronic Arts is being taken private in a historic $55 billion transaction valued at $210 per share, driven by a consortium led by the Saudi Public Investment Fund and Silver Lake. The deal aims to shield the company from gaming gatekeepers like Microsoft and Sony while leveraging AI integration to optimize operations and create independent distribution channels. Concurrent discussions analyze the broader implications for the private equity sector, the strategic shift toward open-source AI models, and the urgent need for federal preemption to avoid a fragmented state-by-state regulatory landscape.
- Y Combinator45 min
The 7 Most Powerful Moats For AI Startups
Jared, Diana, Gary, Tiana, Harjit
Founders now treat defensive moats as existential necessities to combat margin erosion, prioritizing execution speed and specialized engineering over traditional growth hacks. Key strategies include securing non-arbitrageable assets like regulatory approvals, leveraging deep workflow integration to create high switching costs, and adopting "work completed" pricing models to bypass incumbents' automation cannibalization traps. Ultimately, these tactics focus on emerging as sustainable advantages only after validating solutions to critical customer pain points, rather than relying on long-term strategic forecasting.