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  1. Milken Institute33 min

    Art of Storytelling: Shaping Culture, Identity, & Global Impact | Middle East and Africa Summit 2024

    Louise Tabbiner, Edward Norton, Elie Saab Jr.

    Moderated by Milken Institute Senior Advisor Louise Tabiner, Edward Norton and Elie Saab Jr. examined how authentic storytelling drives business strategy, cultural identity, and global impact. Norton emphasized the power of narrative to address ecological challenges and foster personal balance, while Saab Jr. detailed the family-owned brand's non-negotiable focus on transparency and organic expansion into new verticals. The panelists concluded that successful persuasion requires refining narratives through personal experience and leveraging shared human experiences, such as sports and heritage, to bridge cultural divides.

  2. a16z31 min

    How Gusto Used Customer Input to Scale Growth with Tomer London

    Tomer London, Seema Amble

    Gusto, a nearly $10 billion payroll and HR platform founded by Tomer London and his Stanford classmates, initially targeted a hyper-specific niche of California-based, non-hourly businesses to validate its product through manual, high-effort outreach. The company strategically leveraged self-serve economics and unexpected adoption by accountants as a key distribution channel, scaling from a concierge onboarding phase for its first 16 clients to an automated platform serving over 300,000 U.S. firms. By maintaining strict unit economics and a weekly growth target of 15–20 percent without paid acquisition, Gusto established a sustainable product-led model that evolved into an all-in-one system for both employees and contractors.

  3. Milken Institute20 min

    A Conversation with CMS Director of Medicare Meena Seshamani | Future of Health Summit 2024

    Meena Seshamani, Bertha Coombs

    A multidisciplinary team comprising experts from drug pricing, pharmacy, and economics has implemented health care reforms focused on treating developmental issues, chronic illnesses, and behavioral health within the Medicare and Medicaid systems. These initiatives, which include updating risk adjustment methodologies and navigating the Inflation Reduction Act, aim to reduce prescription drug costs for seniors and integrate services to address over 400,000 additional conditions. With a target deadline of September 1st for international financial agreements, the organization plans to execute these changes over five to eight months while utilizing new communication platforms and patient feedback to ensure system stability.

  4. Sequoia Capital39 min

    Using AI to Build “Self-Driving Money” ft Ramp CEO Eric Glyman

    Eric Glyman, Ravi Gupta, Sonya Huang

    Ramp CEO Eric Gleiman champions a "zero-touch automation" strategy that utilizes large language models to execute invisible financial tasks, allowing over 25,000 companies to automate expense reporting and achieve average annual savings of 5%. This approach replaces traditional chatbot interfaces with self-driving money systems that automatically classify vendors and complete reports, marking a shift from routine data entry to high-value strategic work for finance leaders. By prioritizing enduring customer pains over temporary tech trends, the company positions itself to disrupt legacy financial institutions through non-bank innovation that mimics the operational efficiency of "self-driving" transformations in other industries.

  5. Milken Institute53 min

    Health Care of the Future | Future of Health Summit 2024

    Michael Milken, Alex Azar, Buddy Carter, Diana DeGette, Renee Wegrzyn

    The event detailed how ARPA-H and legislative initiatives like "Cures 2.0" are addressing systemic healthcare challenges by funding high-risk biomedical innovations and ensuring pharmaceutical independence. Key figures including Rep. Diana DeGette and Rep. Chris Carter highlighted strategies to reform Medicare Advantage payment models and repatriate drug manufacturing to counter supply chain vulnerabilities. The panel concluded with a call for increased federal investment in translational science and a broader call for business leaders to enter government to sustain the pace of medical breakthroughs.

  6. Milken Institute20 min

    A Conversation with FDA Commissioner Robert Califf | Future of Health Summit 2024

    Robert Califf, Esther Krofah

    Commissioner Califf reflects on his tenure managing the Abbott infant formula recall and reorganizing the FDA Food Program, emphasizing that the agency faces a healthcare delivery crisis rather than an innovation deficit despite the U.S. global leadership in scientific advancement. He advocates for shifting regulatory focus from pre-approval trials to post-market pragmatic studies and new frameworks for AI decision support to address systemic biases and monitor uncontrolled algorithmic drift in clinical environments. Califf concludes by defining essential traits for future leadership, prioritizing executive listening skills and a commitment to high-quality evidence generation while maintaining a strict separation between science-based product decisions and politically influenced policy mandates.

  7. The Economist21 min

    Moment of truce: a ceasefire in the Middle East

    Rosie Bloor, Greg Karlstrom, Anjani Trivedi, Sophie Pedder

    A US and France-brokered 60-day ceasefire entered into force, mandating Hezbollah's withdrawal north of the Litani River and Israel's gradual troop pullback while facing skepticism over Lebanon's economic stability and military capacity. In Europe, the bankruptcy of battery maker Northvolt has exposed structural vulnerabilities in the region's EV supply chain, threatening to increase reliance on Chinese-dominated manufacturing and delay green energy targets. Concurrently, French media and public discourse are reshaping societal norms regarding aging, with cultural figures like Sylvie from *Emily in Paris* challenging traditional beauty standards to promote confidence and visibility for women over 60.

  8. All-In Podcast8 min

    DOGE's Opportunity: Unleash American Growth by Cutting Regulations

    Chamath, Jason, Friedberg, Nick, J. Cal, Sachs, Freiburg

    DOGE leaders Elon Musk and Chamath Palihapitiya propose a radical restructuring of the federal government by implementing a public performance leaderboard to expose inefficiencies and mandating automatic expiration dates for all regulations. They advocate for wiping the entire existing regulatory code to zero and replacing it with a simplified flat tax system, strategies projected to stimulate 4-5% GDP growth by eliminating bureaucratic redundancies. This approach shifts the federal operational model from regulatory expansion to deregulation, aiming to correct economic stagnation while holding public employees accountable for past excesses under a new incentive framework.

  9. Milken Institute58 min

    Innovation for All: Strategies for Maximizing Impact | Future of Health Summit 2024

    Matthew Herper, Jay Bradner, Debi Brooks, Lisa D. Earnhardt, Elizabeth Fowler, Marc Samuels

    This event synthesized breakthroughs in Parkinson's biomarker detection, the genetic discovery of obesity-protective alleles, and strategies to expand medical device access for underserved populations. Industry leaders and regulators discussed how these scientific advances confront systemic barriers in delivery and reimbursement, particularly regarding the high costs of gene therapies and the misalignment of current billing models with preventative care. The consensus emphasized that future progress depends on shifting focus from pure biological innovation to collaborative frameworks that ensure scalable manufacturing, equitable access, and payment reforms based on patient outcomes.

  10. Sequoia Capital1h 3m

    Getting the Most From AI With Multiple Custom Agents ft Dust’s Gabriel Hubert and Stanislas Polu

    Gabriel Hubert, Stanislas Polu, Konstantine Buhler, Pat Grady

    Dust positions itself as a horizontal platform for AI adoption, predicting a bimodal future where enterprise users seamlessly switch between frontier APIs and local models to navigate varying technological plateaus. By prioritizing product-market fit over proprietary model training and leveraging Retrieval-Augmented Generation to unlock data silos, the company enables diverse teams to build specialized agents that augment human work rather than replace it. This strategy targets a demographic of young power users and aims to scale from isolated pilots to organization-wide adoption, facilitating everything from cross-functional translation to global expansion despite current limitations in reasoning breakthroughs.

  11. All-In Podcast1h 10m

    DOGE unveils a roadmap, Unlocking GDP Growth, WW3 escalation, Fat cell memory

    Chamath, Friedberg, Jason Calacanis, David Sacks

    Elon Musk and Vivek Ramaswamy's Department of Government Efficiency plans to eliminate $500 billion in unauthorized federal spending over an 18-month period by leveraging recent Supreme Court rulings to bypass traditional legislative approval processes. The initiative targets regulatory rollbacks through executive audits and temporary payment suspensions while facing anticipated legal challenges from entrenched bureaucratic interests and internal Republican resistance to deficit reduction. Concurrently, the discussion highlights global security risks regarding Western missile capabilities in the Ukraine-Russia conflict and presents scientific breakthroughs in epigenetics that explain persistent obesity mechanisms despite weight loss.

  12. Goldman Sachs33 min

    Primavera Capital’s Fred Hu on China’s economic trajectory

    Fred Hu, Kevin Sneader

    Following a historic equity rally triggered by unprecedented joint policy directives from China's financial regulators and top leadership, Fred Hu of Primavera Capital Group characterizes the current market upturn as a normalization phase with substantial catch-up potential. Hu anticipates that near-term fiscal stimulus will target household consumption while arguing that long-term confidence depends on structural reforms that reassure the private sector and accelerate innovation in fields where China currently lags in generative AI. Beyond immediate market dynamics, the event highlights China's undisputed leadership in green energy and a massive demographic opportunity within its 800 million-person middle class, which analysts project will soon drive private consumption to become the primary engine of national GDP growth.

  13. Y Combinator42 min

    Vertical AI Agents Could Be 10X Bigger Than SaaS

    Gary, Jared Harge, Diana, Mark Mandelbaum, Aaron Cannon, Mike, Brett Taylor, Parker Conrad, Matt McGinnis, Salient, VAPI, Rippling, Speedy Brand, OpenAI, Claude, Melanie Warrick, Nico, A Priori, Capital.ai, PowerHelp, Giga ML, Zepto, Mementic, Rainforest QA, Triplebyte, Outset, Vector Shift, Mark Benioff, Paul Graham, Travis, Jake Heller, Flo Cravello, Tia, Hashi Roginio, Mark Mirchandani, Francesc Campoy Flores

    Jared Harge projects that vertical AI agents will trigger a $300 billion+ market surge by displacing human labor in specialized enterprise functions, mirroring the historical success of B2B SaaS where general-purpose incumbents cannot master niche domain complexities. While competitors like Mark Mandelbaum note exceptions such as Rippling's horizontal platform strategy, startups are advised to target high-value, repetitive workflows—from automated recruiting to debt collection—rather than competing in obvious consumer applications where incumbents like Google retain dominance. This shift from basic software wrappers to full-stack agents is expected to expand organizational leadership span and create unicorns ten times larger than previous software predecessors by integrating complex domain knowledge directly into autonomous decision-making tools.

  14. Sourcery with Molly O'Shea35 min

    How Armada Is Powering AI at the Edge | A Conversation with CEO Dan Wright

    Dan Wright, Molly O'Shea, Jon Runyan, Pradeep Nair

    Founded in 2022 by ex-AppDynamics CEO Dan and other industry veterans, Armada has secured $100 million to deploy its Commander platform, which unifies satellite connectivity, ruggedized mobile data centers known as Galleons, and AI operations for remote environments. The company targets the 70% of the globe beyond standard cellular networks, partnering with Starlink and Microsoft to deliver real-time industrial monitoring and safety solutions across nearly 50 countries. With a leadership team drawn from Microsoft Azure, SpaceX, and Okta, Armada aims to create a global distributed cloud that enables mission-critical AI applications in hostile locations ranging from Antarctica to offshore oil rigs.

  15. Goldman Sachs28 min

    Investing in Sports: A New Media Model

    Nicole Pullen Ross, Dave Dase, Gene Sykes

    Driven by lucrative 20-year media rights deals and the migration of distribution from legacy broadcasters to tech platforms, the sports industry is navigating a valuation surge that currently places the NBA at $76 billion. As cord-cutting erodes traditional cable bundles and regional networks collapse, leagues and legacy broadcasters are restructuring through direct-to-consumer streaming services and modified game rules to maximize subscriber engagement. This fundamental shift, supported by the expansion of sports betting and the growing global influence of athlete personal brands, is projected to continue driving team valuations upward over the next decade.