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  1. All-In Podcast1h 36m

    E73: Late-stage VC markdowns and mistakes, market strategy, Ukraine/Russia update with Brad Gerstner

    Brad Gerstner, Friedberg, Zelenskyy, Putin, Biden, Zakaria, David Sacks

    Brad Gershner, Chamath Palihapitiya, and David Sacks analyze the transition from the 2020–2021 bull market to a normalization phase driven by rising real rates, predicting 50–60% mispricing in late-stage venture valuations and widespread down-round IPOs. The panel introduces the "burn multiple" as a critical governance metric to enforce capital efficiency, while simultaneously warning that geopolitical strategies in Ukraine and a potential US-China recession could exacerbate the upcoming economic downturn. These macroeconomic shifts and valuation corrections are contextualized alongside the upcoming All-In Summit in Miami, where confirmed speakers will address the necessity of stripping away speculative excesses to rebuild resilient business models.

  2. All-In Podcast1h 11m

    E70: EMERGENCY POD! Russia invades Ukraine: Reactions, Putin's ambition, Biden's response and more

    Putin, Biden, Chamath, Calacanis, Friedberg, Jay Kal, Sax, David Sacks

    On February 24, 2022, Vladimir Putin initiated a military invasion of Ukraine while the United States maintained a non-interventionist stance to avoid direct conflict, citing the absence of NATO treaty obligations and historical precedents. Concurrently, the US and its allies deployed severe economic sanctions and cyber warfare against Russia, causing immediate volatility in global markets and the ruble, though experts noted Russia's financial resilience. The event also sparked a broader strategic debate regarding European energy dependency, the urgent need for domestic infrastructure modernization, and the potential long-term impacts on investment valuations and geopolitical alliances.

  3. All-In Podcast1h 25m

    E67: Revisiting Rogan, Canadian truckers' protest, fusion breakthrough, $MSFT's savvy move & more

    Rogan, Phil Hellmuth, Biden, Friedberg, Wyden, Heinrich, Haines, Chamath Palihapitiya, David Sacks

    In a panel discussion featuring Joe Rogan, Chamath Palihapitiya, and David Sacks, the hosts analyze the selective cancellation of Rogan by Spotify alongside the political implications of the Canadian Freedom Convoy and the erosion of civil liberties through warrantless CIA surveillance. The conversation further details significant advancements in nuclear fusion technology, such as JET's energy output record, while contrasting these long-term energy solutions with immediate macroeconomic pressures like rising inflation and declining consumer sentiment. Ultimately, the group argues that current government mandates and media narratives are disproportionately targeting heterodox voices and working-class concerns, warning of a widening schism between political elites and the general public.

  4. All-In Podcast1h 39m

    E66: $FB's big drop, Rogan/Spotify mess, Xi/Putin meetup & supply chain issues with Ryan Petersen

    Rogan, Putin, Ryan Petersen, Xi Jinping, David Sacks, Chamath Palihapitiya, David Friedberg

    In a discussion featuring Flexport's Ryan Peterson, experts analyze global supply chain fractures driven by infrastructure decay, labor inefficiencies, and regulatory bottlenecks that have extended transit times from 50 to 115 days while forcing major corporations to vertically integrate against smaller competitors. The analysis further details how Meta's strategic pivot to the metaverse has destabilized its stock amidst privacy regulation and TikTok competition, while antitrust scrutiny shifts toward Amazon and speech policies as geopolitical tensions solidify a Sino-Russian alliance. Ultimately, the speakers warn of looming inventory gluts and revenue lags in the short term, arguing that US policy must urgently prioritize semiconductor security and port modernization to counter these systemic vulnerabilities.

  5. All-In Podcast1h 14m

    E65: VC markup dynamics, Russia/US tensions over Ukraine, Altos Labs raises $3B, Stripe mafia & more

    Chamath, Putin, Obama, Bill Ackman, Yamanaka, Jason, David Sacks, David Friedberg

    Investors David Friedberg, Jay Hogue, Bill Gurley, and Chamath Palihapitiya analyzed current market volatility, venture capital valuation mechanics, and geopolitical risks while debating the strategic separation of long-term investing from short-term trading. The panelists contrasted the structural disincentives for marking down portfolio companies with a consensus that supply chain disruptions, rather than interest rates, currently pose the primary threat to the US economy. Looking forward, the group identified opportunities in fundamentally strong growth stocks despite sector corrections, warned against NATO expansion escalating the Ukraine conflict, and predicted a rapid resolution to global supply bottlenecks alongside a paradigm shift in biotech age reversal research.

  6. All-In Podcast1h 22m

    E61: 2022 Predictions! Business, politics, science, tech, crypto, & more

    Calacanis, Friedberg, Chamath Palihapitiya, David Sacks, Jay Cal

    In a candid discussion featuring Jason Calacanis, David Sacks, Chamath Palihapitiya, and Ben Freeberg, participants detailed a COVID-19 superspreading event at Sax's party while debating the biological and geopolitical winners and losers of the 2022 landscape. The group forecasted political shifts including Ron DeSantis's re-election and Vladimir Putin's strategic gains, alongside economic predictions favoring small businesses, biotech innovation, and battery metals over traditional payment processors like Visa. Beyond these macro trends, the conversation extended to intense ethical debates regarding animal agriculture, media narrative shifts, and specific industry disruptions such as the potential rise of decentralized finance.

  7. All-In Podcast1h 27m

    E52: Trump's SPAC, peak venture liquidity, tech as an economic ladder, Dems overplaying their hand

    Trump, Chamath, Calacanis, Friedberg, David Sacks

    David Sacks details his weight loss regimen of severe calorie restriction to combat age-related metabolic decline, while the panel analyzes Donald Trump's SPAC merger forming Truth Social as a vehicle leveraging brand value rather than established technology. Amidst unprecedented venture capital liquidity driving a talent war, the discussion contrasts the "new rich" with the old elite, defending tech innovation against cancel culture and critiquing progressive political tactics that risk legislative gridlock. The episode concludes with upcoming announcements regarding an All-In Summit, Palihapitiya's trip to African startup hubs, and personal family news from the hosts.

  8. All-In Podcast1h 33m

    E51: Supply Chain Shortages, Inflation, DeSantis, Ted Sarandos Netflix Memo, Cancel Culture, Fan Q&A

    DeSantis, Ted Sarandos, Chamath, Calacanis, David Sacks, Daniel, Maddie, David Friedberg

    David Sacks and David Friedberg analyze a looming stagflationary crisis driven by port labor disputes, structural wage inflation, and geopolitical fragility, arguing that the Federal Reserve faces a fiscal dilemma where raising interest rates could trigger a debt spiral exceeding 140% of GDP. To address these supply chain constraints, the speakers advocate for skills-based immigration reforms and accelerating automation through quantum computing and biomanufacturing to reduce reliance on volatile global logistics. The discussion further covers regulatory crackdowns on opaque stablecoin operations like Tether, the scientific rationale behind shifting FDA guidelines, and the economic incentives sustaining free speech defenses in the face of cancel culture.

  9. All-In Podcast1h 29m

    Balaji Srinivasan: role of decentralization, China/US breakdown & more

    Balaji Srinivasan, Calacanis, Friedberg, Chamath Palihapitiya, David Sacks

    In episode 48 of the *All In Podcast*, Chamath Palihapitiya, David Sacks, David Friedberg, and guest Balaji Srinivasan analyze the geopolitical clash between China's centralized model and the West's potential for decentralized defense through blockchain. The panel argues that emerging technologies like immutable ledgers must replace corporate journalism and centralized social platforms to ensure truth verification and protect individual liberties against state overreach. They conclude that while the US cannot match China's military strength, it can develop asymmetric advantages by fostering a regulatory environment that accelerates the adoption of decentralized finance and social networks.

  10. All-In Podcast1h 13m

    E46: False Ivermectin narratives, regulatory grift, wartime mentality in solving issues & more

    Rachel Maddow, David Sacks

    Recorded live at the Production Board Symposium 2021, this episode features a panel of scientists, engineers, and investors who critique institutional failures regarding the Ivermectin coverage, vaccine mandates, and climate change infrastructure bills. The speakers contrast the perceived regulatory capture and inefficiency of the U.S. healthcare and defense sectors with the rapid scaling capabilities of wartime mobilization models like the War Production Board, while analyzing geopolitical threats from China and the potential of fusion energy. Furthermore, the discussion outlines the intersection of venture capital, cryptocurrency, and decentralized finance as essential mechanisms for funding innovation and hedging against authoritarian state control, concluding with a call for political engagement by wealthy entrepreneurs to reshape policy.

  11. All-In Podcast1h 24m

    E45: Theranos & VC fraud risks, China bans video games, Texas SB8, Apple app store, CA fires, Rogan

    Rogan, Elizabeth Holmes, Chamath Palihapitiya, David Sacks

    The All-in podcast team discusses the private beta launch of their social audio app Callan, which attracted 10,000 users in its first week, while announcing plans to record their first in-person episode at the TPB Symposium. The hosts analyze the Elizabeth Holmes trial as a symptom of Silicon Valley's lack of diligence and debate the implications of China's video game restrictions and Texas' novel abortion enforcement law. Additionally, the discussion covers Apple's concessions to external subscription links, the escalating climate crisis threatening California's insurance market, and emerging data on vaccine transmission rates during the Delta variant outbreak.

  12. All-In Podcast1h 19m

    E40: A Bestie gets COVID, Delta breakthrough, Billionaire Space Race & more

    Chamath, Calacanis, Friedberg, Richard Branson, Andy Weir, Jeremy England, David Sacks

    Venture capitalist David Sacks details his mild breakthrough Delta infection while discussing declining vaccine efficacy against the highly transmissible variant and the subsequent pressure for population-wide booster shots. Concurrently, the conversation expands to the private space sector's rapid maturation, highlighted by Virgin Galactic's successful commercial flight and surging venture capital investment, which sparks debate over prioritizing space exploration versus resolving terrestrial crises. The hosts further contextualize these developments through discussions on the psychological impact of breakthrough cases, potential policy shifts regarding vaccination mandates, and the emerging economic models of space tourism and satellite infrastructure.

  13. All-In Podcast1h 23m

    E32: Behind the scenes of Elon hosting SNL, CDC failures, America's real-time UBI experiment & more

    Elon, Chamath, Calacanis, Friedberg, Jason, Stanley Druckenmiller, David Sacks

    David Sacks detailed Elon Musk's culturally impactful *SNL* appearance and a viral monologue joke, while also criticizing CDC guidance on outdoor transmission and alleging political collusion with teachers' unions. Macroeconomic analysts Stanley Druckenmiller and Sacks condemned federal overstimulation and California's misallocated surpluses as drivers of inflation and labor shortages. The conversation further explored a potential "Netscape moment" for synthetic biology, highlighting breakthroughs in stem cell therapy and nitrogen-fixing microbes alongside critiques of traditional media's declining influence.

  14. All-In Podcast1h 22m

    E31: Post-vaccination virtue signaling, pandemic lessons, immigration, Caitlyn Jenner for CA & more

    Caitlyn Jenner, David Sacks, David Friedberg

    David Sacks and Chamath Palihapitiya critique pandemic-era policies for relying on excessive conservatism that hindered economic recovery and eroded public trust, while highlighting the critical link between obesity and mortality. The discussion further outlines a shifting political landscape driven by a bipartisan consensus on antitrust enforcement, predicting the breakup of major technology monopolies by 2030 to address threats to democracy. Concluding with observations on local governance, the hosts contrast the safety and reopening trends in Austin against San Francisco, citing the Caitlyn Jenner gubernatorial campaign as a focal point for redefining public safety priorities.

  15. All-In Podcast1h 26m

    E19: Robinhood's GameStop decision: Why did it happen and how can it be prevented in the future?

    David Sacks, Jason, Friedberg, Chamath Palihapitiya

    Hosts analyzed the January 2021 GameStop short squeeze, detailing how Reddit users, Michael Burry, and Ryan Cohen pressured institutional shorts while Robinhood's trading restrictions sparked accusations of market manipulation. The discussion highlighted systemic flaws in clearing mechanisms and payment-for-order-flow models, contrasting the collective power of retail investors with risks of mob behavior and centralized censorship. Additionally, the conversation addressed Chamath Palihapitiya's California recall campaign for Governor Gavin Newsom, framing both financial and political movements as challenges to entrenched elite control.