Dr. Eric Kandel

Dr. Eric Kandel, Nobel Prize-winning Neuroscientist: Talks at GS Session Highlights

Dr. Eric Kandel

A comprehensive analysis of memory systems distinguishes between localized brain functions, such as Broca's and Wernicke's areas, and the dual nature of memory identified in patient H.M. as either explicit or implicit. Research into storage mechanisms reveals that long-term memory relies on the CREB transcription factor and RBAB48 protein to physically grow synaptic connections, while age-related decline stems from a specific deficit in the dentate gyrus distinct from Alzheimer's pathology. This decline is reversible through interventions like injecting osteocalcin or engaging in physical exercise, which boost necessary protein levels to restore cognitive function in aged models.