Karen Knudsen
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- Milken Institute1h 0m
Why Younger People Are Getting Cancer and What We Can Do About It | Future of Health Summit 2024
Dylan Scott, Karen Knudsen, Harlan Levine, Mohit Manrao, Kimryn Rathmell, AmirAli Talasaz
A comprehensive 24-million-person study spanning two decades reveals that 17 of 34 major cancer types are rising significantly among Millennials and Gen X, prompting the American Cancer Society to lower screening thresholds despite critical barriers in adoption and access. To address this "tsunami" of young survivors facing unique fertility, financial, and care challenges, the field is transitioning toward liquid biopsy innovations and multidisciplinary "living" guideline frameworks to bridge the gap between community providers and academic centers. While precision medicine and expanded immunotherapy trials offer hope for improved survival, the crisis persists due to outdated insurance models, systemic disparities, and a significant lag between emerging scientific evidence and updated clinical protocols.
- Milken Institute1h 1m
Prevention and Innovation for a Healthier Tomorrow | Global Conference 2024
Esther Krofah, Robert Bradway, David Feinberg, Karen Knudsen, Meena Seshamani
Representatives from CMS, the American Cancer Society, Oracle Health, and Amgen convened to address the U.S. healthcare system's inefficiencies, noting that while the sector consumes 20% of GDP, chronic disease prevalence and administrative friction continue to drive costs while outcomes remain misaligned. Key strategies outlined include shifting Medicare toward value-based care with a $2,000 prescription cap, leveraging AI tools like the Oracle Digital Clinical Assistant to reduce physician administrative burdens, and advocating for federal reimbursement of multi-cancer early detection to improve survival rates. The panelists reached a consensus that the current fragmented structure is impoding and requires fundamental structural reforms rather than incremental solutions to successfully integrate prevention, innovation, and data interoperability.