Margaret Hamburg
Showing 1–5 of 5 transcripts.
- Milken Institute53 min
Predicting Pandemics: Mobilizing an Active Global Surveillance System
Dan Diamond, Francis deSouza, Margaret Hamburg, John Nkengasong
Despite unprecedented advances in viral sequencing speed during the COVID-19 pandemic, experts identified critical systemic gaps in global pathogen surveillance that relied on serendipitous discovery rather than proactive networks. Highlighting stark disparities between nations like South Korea and underserved regions in Africa, leaders such as Francis D'Souza and Dr. Hamburg outlined a $100 million Genomics Initiative and advocated for a sustainable public-private partnership to fund a "One Health" approach. This collaborative strategy aims to integrate human, animal, and environmental monitoring through modern genomic technologies, ensuring real-time detection of emerging threats while addressing the political and structural barriers that hindered previous pandemic responses.
- Milken Institute57 min
Making Influenza History: The Quest for a Universal Vaccine
Michael Specter, Rick Bright, Anthony Fauci, Bruce Gellin, Margaret Hamburg, Casey Wright
Annual seasonal influenza causes approximately 650,000 global deaths and imposes a $36.1 billion economic burden in the United States alone, yet current egg-based production methods and fragmented research efforts hinder the development of a universal vaccine. Although advances in structure-based design and synthetic mRNA technologies offer pathways to stabilize conserved viral targets and eliminate annual vaccination, commercial disincentives and outdated regulatory frameworks continue to stall progress. To overcome these systemic barriers, experts advocate for a dedicated global entity and sustained funding initiatives, such as a proposed $1 billion legislative package, to coordinate interdisciplinary collaboration and de-risk the shift toward rapid-response, long-lasting immunization platforms.
- Milken Institute1h 2m
Outsmarting Superbugs: What Are the Alternatives?
Margaret Hamburg, Matthew Hepburn, Peter Jackson, Nancy Knight, Jeanette Mucha, Peter Piot, Peggy Hamburg, David Wallace, Lance Price
Global leaders and organizations including the WHO, CDC, and the U.K. government are coordinating a multi-faceted response to antimicrobial resistance, which threatens to cause 10 million annual deaths by 2050 and mimic the 2008 financial crisis through massive economic losses. Innovative initiatives such as the CDC's AMR Challenge, Carb-X's $80 million funding for 40 development projects, and the U.K.'s "pull incentive" trial aim to revitalize the antibiotic pipeline by supporting SMEs and rewarding disease prevention rather than sales volume. Despite these advances, experts warn that rigid intellectual property laws, inadequate wastewater treatment, and capital gaps in microbiome startups hinder the deployment of new therapies needed to combat untreatable superbugs like drug-resistant tuberculosis.
- Milken Institute1h 1m
Creating a Culture of Biomedical Innovation
Mike Rea, Christopher Austin, Amitabh Chandra, Margaret Hamburg, Jennifer Miller, Jason Spangler
A cross-sector panel comprising leaders from NCATS, the FDA, Harvard, and Amgen redefined biomedical innovation as a value-driven process that balances patient outcomes with accessibility and ethical trust. By advocating for a collaborative culture that normalizes failure and breaks down silos between research, regulation, and reimbursement, the group proposed shifting metrics from simple speed to societal acceleration and integrity. The discussion ultimately highlighted critical misalignments in R&D funding, noting that commercial incentives currently neglect major disease burdens like mental health and neglected tropical diseases, necessitating a structural shift toward public-sector leadership.
- Milken Institute1h 4m
Enterprising Families at the Forefront of Business in Mexico
Cate Ambrose, Alonso Díaz Etienne, Gina Diez Barroso, Nicolás Mariscal Servitje, Margaret Hamburg, Margot Santos
The Latin American Private Capital Association (LAFCA) highlighted a demographic and institutional shift in Mexico's economy, where a young, US-educated generation is driving family offices and corporations like Grupo Bimbo and Hebera Capital to expand globally while prioritizing governance and sustainability. Panelists detailed strategies from Grupo Dyarik's educational reforms in Mexico City and Miami to Grupo Marños' infrastructure ethics, illustrating how these entities are leveraging local talent to counterbalance market uncertainty ahead of the 2018 presidential election. Despite rhetoric regarding US-Mexico relations, business leaders emphasized robust checks and balances and a surge in private pension fund participation, positioning Mexico as a stable, competitive hub for energy, infrastructure, and technology investment.