Latest Interviews
Showing 1036–1050 of 1,099 interview transcripts.
Clear all filters- Milken Institute38 min
A Conversation with David Miliband
David Miliband, Jayne Van Hoen, Adam Boulton
At a recent event, International Rescue Committee leader David Miliband outlined the global displacement crisis involving 65 million people while detailing the organization's $100 million initiative to treat child trauma in the Middle East. Miliband sharply critiqued the Trump administration's withdrawal from international agreements and the UK's hard Brexit as destabilizing forces that exacerbate conflict and hinder effective humanitarian aid. He concluded by urging private sector engagement to shift refugee support from emergency relief to sustainable economic integration, arguing that displacement driven by fragile states and climate change will define the 21st century.
- Goldman Sachs21 min
Talks at GS – Ray Dalio: Principles for Success
Ray Dalio details the evolution of his investment philosophy and the "idea meritocracy" culture at Bridgewater Associates, where radical transparency and believability-weighted protocols replace hierarchical decision-making to drive market success. He advocates converting personal principles into algorithms to harness artificial intelligence as a partner for processing vast data, while emphasizing that human intuition remains essential for unique strategic connections. Dalio further explains how Transcendental Meditation cultivates the emotional humility required to implement these rigorous systems and discusses the challenges of hiring individuals who can adapt to such a non-bureaucratic environment.
- Y Combinator28 min
Keith Schacht and Doug Peltz on What Traction Feels Like - at YC Edtech Night
Keith Schacht, Doug Peltz, Geoff Ralston, Tim, Blake
Founded by former teacher Doug Peltz and entrepreneur Keith Schacht, Mystery Science delivers an interactive, pre-recorded science curriculum that acts as a virtual co-teacher for K-5 educators lacking subject expertise. The company secured a $2 million Series A round and entered Y Combinator in 2017 after validating a viral, teacher-led adoption model that currently operates in over 10% of U.S. schools. By replacing traditional textbooks with evidence-based storytelling, Mystery Science has bypassed the need for heavy sales infrastructure to become a dominant supplemental resource in a market where 95% of elementary schools lack dedicated science staff.
- The Economist21 min
Welcome to the startup jungle
Janos Amstutz, Sandro, Isabel, Vinicius Guzmão, Chris Haley, Corrie Vu
Entrepreneurs in the UK and Brazil navigate a high-risk environment where intense competition and a scarcity of venture capital force rapid pivots, as exemplified by HoloMe founder Janos Amstutz securing commercial traction through strategic partnerships after failing to secure immediate investment. Simultaneously, the Medroom team in Brazil overcame a last-minute technical crisis to successfully demonstrate their VR medical training tool to major university partners, proving the viability of their solution for reducing patient errors. These divergent case studies highlight how founders must combine technical iteration, market validation, and sheer determination to survive the transition from self-funded prototypes to commercially sustainable businesses.
- Y Combinator26 min
Sarah Chou on Finding Product-Market Fit in the Education Industry - at YC Edtech Night
Sarah Chou, Karen Lien, Chen, Preston, Jeff, Tim, Chad
Informed K-12, a B2B SaaS platform founded by CEO Sarah and CTO Chen, facilitates the digitization of administrative workflows for school districts by managing over 600 distinct forms ranging from mileage reimbursements to travel authorizations. After pivoting from an unsuccessful teacher-focused Q&A model, the company established a repeatable sales process targeting Chief Business Officials and Assistant Superintendents to validate demand for a system-level paperwork solution. With 22 employees now operating in 22 distinct markets, the firm leverages direct relationship-building strategies and rigorous data privacy standards to modernize back-office operations for districts navigating budget constraints and staffing challenges.
- Milken Institute41 min
A Conversation with Steve Ballmer
Steve Ballmer, a Harvard graduate who left Stanford to join Bill Gates at Microsoft, has applied his strategic leadership and data-driven philosophy to diverse sectors including technology, philanthropy, and sports. He founded USAFacts.org to provide nonpartisan government data that holds officials accountable and aims to improve economic mobility, while simultaneously revitalizing the LA Clippers with a focus on championship performance and operational transparency. Ballmer's approach consistently emphasizes the necessity of high performance, clear vision, and measurable outcomes across all his current ventures.
- Milken Institute35 min
A Conversation with FDA Commissioner Scott Gottlieb
Former FDA Commissioner Scott Gottlieb outlines a multifaceted regulatory strategy addressing the opioid epidemic, tobacco addiction, and the aftermath of Hurricane María on Puerto Rico's critical medical manufacturing sector. He emphasizes adapting regulatory frameworks for emerging technologies like artificial intelligence and digital health tools while prioritizing the prevention of medical misinformation and product shortages. The discussion highlights a shift toward reducing review cycles, de-risking early-stage development, and utilizing post-market surveillance to balance safety with innovation.
- Milken Institute34 min
A Conversation with PepsiCo CEO Indra Nooyi
Indra Nooyi, Michael Milken, Andrew, Mike
PepsiCo CEO Indra Nooyi transformed the beverage and snack giant through "Performance with Purpose," a strategy that integrated social and environmental sustainability into core operations while shifting the revenue portfolio toward healthier product lines. This cultural overhaul was driven by scientific leadership under Chief Scientific Officer Dr. Mahmood Khan and reinforced by tying executive compensation to specific nutritional and environmental goals. Nooyi further extended the company's impact by forging partnerships with healthcare institutions to improve access for underserved veterans and advocating for systemic policy changes to address chronic disease and nutritional equity.
- Goldman Sachs23 min
Talks at GS – Ambassador Christopher Hill: Then & Now – The North Korean Nuclear Crisis
North Korea has shifted from historical negotiation attempts to a strategy under Kim Jong-un that legally enshrines nuclear weapons to decouple U.S. forces from its allies while developing solid-fuel missiles capable of threatening the American mainland. Addressing this evolving threat requires a multi-pronged approach combining stringent U.S.-led sanctions, cyber operations, and renewed diplomatic efforts, all while navigating China's internal conflict between economic interests and security fears of regime collapse. Without sustained global cooperation and military reassurances for South Korea and Japan, the risk of miscalculation remains high as Pyongyang continues to advance its nuclear capabilities.
- Milken Institute40 min
Women Leaders’ Summit:A Conversation with Al Gore: How to Inspire a Movement
At a Milken Institute Women's Summit, former Vice President Al Gore discussed his 2000 election concession, his journey into climate advocacy, and the urgent drivers of the current ecological crisis during the screening of *An Inconvenient Sequel: Truth to Power*. Gore highlighted how rapid technological cost reductions and shifting investor priorities are accelerating a global transition toward electrification and renewables in major economies like India and China, while emphasizing that diverse perspectives and authentic passion are critical for effective communication. The event concluded with a call to action for the investor community to leverage capital and inclusive leadership to secure a sustainable future against the backdrop of a rapidly warming planet.
- Goldman Sachs21 min
Talks at GS – Tony Blinken: Diplomacy: The First Response
Former Deputy Secretary of State Tony Blinken outlines a foreign policy philosophy where robust diplomacy serves as the essential first response to prevent conflicts from escalating into costly military engagements. He details critical assessments of recent U.S. strategies, noting that the Iran Nuclear Deal effectively delayed nuclear threats while criticizing the withdrawal from that agreement as a strategic error. Blinken further emphasizes that effective statecraft requires balancing humility regarding intervention limits with a commitment to American values of dignity, as seen in his reflection on the failures in Syria and the complexities surrounding North Korea and China.
- Y Combinator41 min
Elizabeth Iorns on Biotech Companies in YC
Elizabeth Iorns, Craig Cannon, Elizabeth Lyons
Science Exchange founder and CEO Elizabeth Lyons discusses how Y Combinator accelerates biotech innovation by prioritizing technology de-risking and capital access over traditional market validation. The program addresses the surplus of PhDs entering entrepreneurship by guiding scientists through complex intellectual property licensing and connecting them with Silicon Valley investors seeking deep domain expertise. Current strategic focuses include leveraging AI for drug toxicity prediction, advancing CRISPR applications for genetic editing, and navigating the clinical trial design challenges inherent in longevity research.
- Y Combinator43 min
Spotting Ecommerce Trends in Shipping Data - Laura Behrens Wu
Laura Behrens Wu, Craig Cannon
Founded by Laura in 2013 to bridge the technology gap in logistics, Shippo serves as a RESTful API platform aggregating shipping providers for e-commerce merchants from SMBs to enterprise marketplaces like eBay. The company mitigates complex regulatory risks and carrier inconsistencies while offering specialized insurance and tracking features to reduce cart abandonment and support niche product categories. With a global team of approximately 65 employees, Shippo advises B2B entrepreneurs to target inefficient infrastructure problems, having successfully scaled by positioning its "unsexy" shipping solution within the broader high-growth narrative of e-commerce.
- Y Combinator44 min
The CEO Who Pays Employees to De-Locate From the Bay
In March, Zapier launched a "delocation" program offering $10,000 to incentivize employees to leave the Bay Area, a move that attracted 30% more applicants but resulted in zero successful relocations while expanding the company's global reach. Concurrently, the 95-person all-remote organization is navigating its transition from internal promotions to hiring external management talent at the 100-employee mark, utilizing the "Manager Tools" framework and "Airbnb onboarding" to integrate new leaders. This strategic scaling supports the recent launch of a "Teams" product for enterprise clients, leveraging Zapier's extensive integration library and high retention rates to compete against well-funded rivals without relying on venture capital.
- Y Combinator27 min
Founders of Science Exchange, Goldbely, and The Flex Company Discuss Fundraising
Kat Manalac, Elizabeth Iorns, Vanessa Torrivilla, Erica Jensen, Elizabeth Lyons
Hosted by Kat, a panel featuring YC alumni founders Elizabeth Lyons, Vanessa Torribilla, and Erica examined fundraising hurdles across diverse sectors, revealing that initial seed rounds consistently register as the most difficult stage. The founders detailed a strategic shift from vision-based narratives to rigorous data preparation for Series A, while offering specific tactics for overcoming gender bias and managing team resources to prevent metric stagnation. Ultimately, the discussion emphasized the necessity of aligning investor outreach with relevant demographics and maintaining founder well-being to sustain long-term growth.