Latest Interviews
Showing 181–195 of 1,030 transcripts.
Clear all filters- Milken Institute6 min
LeadersLink Kapila Viges
Kapila Vygis, CEO of the MPN Research Foundation, leveraged the LeadersLink program to secure mentorship and partnerships necessary for establishing a large-scale real-world evidence registry for myeloproliferative neoplasms. This initiative aims to collect electronic medical records to identify disease progression biomarkers and validate "progression-free survival" as a clinical trial endpoint for the 300,000 U.S. patients affected by these rare blood cancers. By adopting a phased roadmap developed with IQVIA and input from diverse stakeholders, the foundation is addressing data quality and cost sustainability to ultimately create curative-focused treatment strategies.
- Milken Institute6 min
LeadersLink Eszter Hars
Esther Harst, a molecular biologist and CEO of the Schwarzman-Diamond Syndrome Alliance, is deploying a patient-entered data platform to address the critical lack of "patient voice" insights in treating this rare genetic disorder that causes fatal leukemia in many patients. The initiative has secured IRB approval and is preparing to launch a pilot study to mobilize the community, facilitate clinical trial matchmaking, and catalyze global collaborations through an open architecture. Building on over 20 years of biotech experience, Harst aims to expand the program to the entire SDS community early next year after validating data utility and patient trust during the pilot phase.
- The Economist10 min
Is China the new superpower?
Zanny Minton Beddoes, Edward Carr, Ant, David, Ed, Alice
The analysis examines the People's Liberation Army's advanced regional military capabilities and manufacturing dominance while highlighting severe internal economic stagnation, including three years of deflation and rising youth unemployment. Although China lacks the global projection power of the United States, its strategic focus on national security and superior hypersonic technology positions it to dominate the Indo-Pacific region. Experts conclude that while Beijing will achieve significant geopolitical strength, its long-term stability faces challenges from domestic discontent and an overreliance on foreign markets that it cannot fully control.
- The Economist8 min
Why Syria might face another uprising
President Ahmad al-Shara has secured significant international diplomatic gains and sanctions relief while simultaneously centralizing power through shadow institutions that marginalize the Alawite and Druze communities. This governance strategy has exacerbated sectarian tensions, triggering over 1,500 deaths in recent violence and driving 25,000 former regime affiliates to flee as they organize new insurgencies. Despite restoring civil liberties and dismantling the Assad-era secret police, the administration's failure to provide transitional justice or economic stability threatens to destabilize the state and negate its diplomatic achievements.
- Goldman Sachs10 min
Why the Dollar Could Drop
Goldman Sachs analysts project a 5% to 10% depreciation of the U.S. dollar in the first half of next year driven by shifting fiscal concerns and the resumption of economic data releases. Market expectations for an immediate Federal Reserve rate cut and the upcoming announcement of the Trump administration's Fed Chair nominee are anticipated to accelerate a rebalancing of global allocations away from hard dollar assets. Consequently, trading strategies are increasingly favoring high-yielding emerging market currencies in Brazil and Mexico over developed market alternatives, while betting on long-term Chinese currency appreciation amid historically low volatility.
- Goldman Sachs18 min
Across America with Goldman Sachs 10,000 Small Businesses
Jill Bomarito, Bill Michaels, Jenny Steffensmeyer
The Goldman Sachs 10,000 Small Businesses program functions as a strategic "mini MBA" that equips entrepreneurs like Jill Bomarito, Bill Michaels, and Jenny Steffensmeyer with the framework to transition from daily operations to high-level business management. Through this initiative, case study participants achieved significant scale by addressing critical gaps in cash flow, marketing, and leadership, resulting in sales growth ranging from 20% to tenfold and facilitating shifts from local to international markets. Beyond individual financial gains, the curriculum fosters a supportive peer network that empowers graduates to advocate for small business policy changes and secure their enterprises' long-term succession planning.
- The Economist7 min
Has the world reached “peak Trump”?
Trump, John Bolton, David Rennie
A recent analysis challenges foreign expectations of normalizing Trump's political influence, highlighting instead a diminishing Republican Party grip evidenced by the rejection of filibuster-ending calls and internal revolts over the Jeffrey Epstein scandal. While acknowledging significant institutional damage characterized by a "retribution presidency," the speaker asserts that Trump functions more as a destructive force akin to Pompey rather than an authoritarian capable of constitutional seizure. Consequently, the assessment concludes that although current policies require urgent correction, the underlying American system remains resilient enough to eventually repair the damage through sustained effort and long-term democratic stability.
- Goldman Sachs7 min
Why Stocks Are Getting Wild
Driven by surging expectations of a Federal Reserve rate cut, equity markets are experiencing heightened volatility that has prompted investors to rotate capital from information technology into defensive sectors like healthcare and financials. Systematic momentum triggers and reduced liquidity have created selling pressure estimated at up to $60 billion in the near term, while strategists recommend hedging large-cap concentration through equal-weighted indices and VIX call spreads to mitigate downside risk.
- Goldman Sachs17 min
What’s Driving the Surge in Deal-Making?
Stephan Feldgoise, Allison Nathan, Stefan Feldgauis
Goldman Sachs reports that 2025 witnessed a historic surge in M&A activity, with billion-dollar transactions doubling and late-year volumes matching 2021 peaks despite tariff-related slowdowns. This resilience was driven by the convergence of aggressive buyer appetites, widened capital markets, and a strategic pivot by boards toward long-term AI and biotech consolidation across the Americas and Europe. Looking ahead to 2026, the firm maintains a cautiously bullish outlook anticipating sustained deal mandates, though geopolitical instability and credit market volatility remain the primary risks to this trajectory.
- Goldman Sachs16 min
The Apollo Theater’s Michelle Ebanks: Preserving Legacy and Celebrating Harlem's Cultural Scene
Apollo Theater President and CEO Michelle E. Banks, joined by Megan Hogan, outlines the historic venue's evolution from a 1934 Harlem Renaissance hub into a modern civic engine that blends performing arts with social advocacy. The institution sustains this mission through a hybrid financial model that funds artistic risk alongside voter registration and education initiatives, while innovating via omni-channel content strategies to reach global audiences. Leadership emphasizes that the organization's relevance depends on deep community accountability, successfully leveraging its legacy to launch careers ranging from Ella Fitzgerald to contemporary artists like Emmanuel Gerard.
- The Economist8 min
How strong is Iran’s regime?
Nicolas Pelham, Adam Roberts, Nick, Ed
Iran's strategic pivot from a proxy-heavy "forward defense" to a missile-centric approach follows the erosion of its Syrian alliances, while the regime grapples with Supreme Leader Ali Khamenei's frailty and a shifting succession landscape dominated by factional money rather than ideology. To maintain power amidst a secular populace, the leadership is adopting nationalist narratives and rebranding the nuclear program as a permanent national asset, signaling a retreat from revolutionary theocracy. This reinvention faces an existential conflict between the public's desire for global integration and the Islamic Revolutionary Guard Corps' vested interest in preserving a closed economy that fuels its monopolies.
- Sequoia Capital11 min
Bolt ft. Markus Villig - From Bootstrapping in Estonia to a Global Leader in Mobility
Bolt, Markus Villig, Jevgeni Kabanov, Pavel Karagjaur, Andrew Reed, Roelof Botha
Founded by Markus Villig in 2013 with a €5,000 loan, Bolt transformed from a local Estonian initiative into a global competitor by pivoting away from traditional taxi fleets to exclusively partner with independent drivers. The company accelerated its international growth by abandoning geographical biases for data-driven market selection, eventually deriving over 50% of its business from emerging African markets, while simultaneously launching food delivery services to diversify its portfolio. During the 2020 pandemic, Bolt preserved its operational capacity by implementing company-wide salary reductions instead of layoffs, a strategy that enabled it to triple its market share and overtake paralyzed competitors during the subsequent recovery.
- The Economist8 min
Why the world’s population is heading for collapse
Mike, Henry, Corbin Duncan, Karen Richmond Jones
Global fertility rates are converging below replacement levels across two-thirds of the world, driven by a societal trend in lower-income nations rather than a temporary fluctuation. While the UN projects a population peak of 10 billion in the 2080s based on assumed recovery, alternative models indicate that sustained low fertility could bring this peak forward to the mid-21st century, precipitating severe population losses in regions like East Asia. This demographic shift also reflects complex outcomes in the United States, where declining teen births and delayed childbearing among educated women have altered age structures without signaling a universal rejection of parenthood.
- Milken Institute16 min
Conversation with H.E. Majid Al Suwaidi, CEO of ALTÉRRA | Global Investors' Symposium São Paulo
Founded at COP28 by former Director-General Majid Al Suedi and major financial partners Brookfield, TPG, and BlackRock, Altera is a $30 billion climate investment vehicle designed to mobilize an additional $250 billion from the private sector over the next three to five years. The fund operates a dual mandate splitting capital between a global Transformation Fund and a dedicated Global South Fund, with a strategic focus on clean energy including nuclear power, industrial decarbonization, and emerging climate technologies. As of now, the entity has deployed capacity equivalent to 90 gigawatts across five continents while generating commercial returns that exceed sector expectations, validating its model to attract further institutional co-investment ahead of COP30.
- All-In Podcast13 min
How Chamath Optimized His Health
Chamath, Ron, Dr. Carlsberg, Dr. London, Sean
Motivated by personal tragedies and a desire to optimize a finite lifespan, the speaker utilized advanced medical imaging and genetic analysis to reframe a decade of statin usage as a necessary preventative measure against atherosclerosis. While cardiac calcium scores indicate a near-zero short-term heart attack risk, detailed scans revealed a significant rise in non-calcified plaque and notable muscle loss, prompting a strategic focus on physical conditioning and continued monitoring. Complementing this personal health journey, the speaker addressed corporate leadership challenges at Shopify and the 80/90 office, emphasizing the critical role of in-person alignment in minimizing strategic drift and maintaining purpose within ambitious ventures.