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  1. Y Combinator3h 39m

    Female Founders Conference - New York

    Jessica Livingston, Kathryn Minshew, Alex Cavoulacos, Mariya Nurislamova, Reshma Shetty, Shan-Lyn Ma, Reham Fagiri, Tiffani Ashley Bell, Alana Branston, Katherine Minshew, Kirsty Nathoo, Adora, Stephanie, Holly Liu, Sharon Pope, Kat Mignolet, Matthew, Carolyn

    Y Combinator and a diverse panel of founders, including Jessica Livingston and representatives from Zola and Scentbird, convened to discuss scalable startup strategies that prioritize values alignment, efficient hiring, and rapid product-market fit validation. The discussion highlighted critical insights such as the dangers of bias in "culture fit" evaluations, the necessity of avoiding "crappy yeses" during fundraising, and the importance of maintaining founder-led scrappiness even after significant capital deployment. By contrasting successful pivots in sectors ranging from wedding registries to virtual data science, the event underscored that sustainable growth relies on unique founder traits and disciplined metric management rather than traditional VC heuristics or rapid scaling alone.

  2. Y Combinator1h 33m

    John Preskill on Quantum Computing

    John Preskill, Steven Hawking, Kip Thorne, Craig Cannon

    Established by Richard Feynman's early theoretical work, the field of quantum computing has evolved from theoretical challenges in the 1970s to a practical reality enabled by mid-1990s error correction and recent hardware advancements in superconducting and trapped-ion systems. As current devices approach 100 qubits, they are poised to disrupt public-key cryptography through Shor's algorithm while simultaneously offering transformative capabilities in quantum chemistry simulation and materials science. The industry now focuses on bridging these applications through hybrid classical-quantum systems and developing post-quantum security measures to address the imminent threat to existing encryption standards.

  3. Y Combinator3h 42m

    Startup Investor School Day 4 Live Stream

    Andy Bromberg, Aaron Harris, Ron Conway, Jeff

    The final day of Startup Investor School featured a comprehensive analysis of early-stage investment history by Andy Bromberg, behavioral standards for angel investors presented by Aaron Harris, and a founder-centric investment philosophy from Ron Conway. The session detailed the evolution from traditional venture capital to modern token offerings like ICOs while establishing a strict code of conduct emphasizing reputation, speed, and integrity in deal-making. Ultimately, the event equipped attendees with tools to model SAFE conversions and fostered a network committed to maintaining ecosystem transparency and supporting high-potential founders.

  4. Y Combinator4h 16m

    Startup Investor School Day 3 Live Stream

    Elad Gil, Pejman, Jeff Clavier, Andrea, Ali Partovi

    Day 3 of the Startup Investor School convened five prominent investors, including Elad Gil, Pejman Nozad, Jeff Clavier, Andrea Zurlo, and Ali Partovi, to dissect critical strategies for market selection, team evaluation, and portfolio construction. The speakers emphasized that successful angel investing requires a 10-year horizon, strict risk discipline regarding net worth allocation, and a service-oriented mindset that prioritizes founder support over immediate financial gains. Key consensus points highlighted the necessity of investing in brilliant founders with big ideas regardless of initial market perceptions, maintaining long-term patience through early-stage losses, and building a personal brand rooted in integrity and operational availability.

  5. Y Combinator2h 41m

    Startup Investor School Day 2 Live Stream

    Jeff, Dalton Caldwell, Ben, Matt, Paul Buchheit, Michael Seibel

    The Startup Investor School brings together prominent figures like Jeff, Dalton Caldwell, and Paul Buchheit to distill a contrarian investment philosophy that prioritizes conviction, speed, and founder quality over market size or consensus. Through case studies of exits ranging from Airbnb to Meraki, the event establishes rigorous frameworks for avoiding herd mentality and executing decisive capital allocation with meaningful check sizes. Attendees receive actionable guidance on navigating modern challenges like ICOs while building long-term networks to support high-growth, deep-tech ventures over a ten-year horizon.

  6. Lex Fridman1h 35m

    MIT AGI: Building machines that see, learn, and think like people (Josh Tenenbaum)

    Josh Tenenbaum

    Josh Tenenbaum and the Center for Brains, Minds, and Machines argue that current deep learning systems are limited specialized tools that fail to replicate human general intelligence due to a lack of common sense and world modeling. To achieve true Artificial General Intelligence, the proposal advocates for a reverse-engineering approach that integrates cognitive science with engineering to build probabilistic programs capable of "programming" internal models of physics and psychology. This methodology aims to bridge the gap between industry's data-driven pattern recognition and the foundational, low-data learning mechanisms observed in human infants.

  7. Milken Institute1h 38m

    A Conversation with Ray Dalio and Michael Milken

    Ray Dalio, Michael Milken

    Ray Dalio outlines his journey from a 1960s caddie to the architect of Bridgewater's "idea meritocracy," a philosophy forged after a costly 1982 sovereign debt mistake forced him to prioritize objective disagreement over ego. Drawing on historical cycles like the 1974 market crash and 1937 recession, Dalio warns of current parallels in wealth disparity and pension funding gaps while critiquing Bitcoin as a speculative bubble despite China's engineering strengths. His analysis concludes that future economic resilience depends on radical transparency, automation-ready skills, and recognizing that sustainable wealth is a byproduct of value creation rather than an end goal.

  8. Jane Street1h 38m

    Yudkowsky vs Hanson — Singularity Debate

    Yudkowsky, Hanson

    Eliezer Yudkowsky and Robin Hanson debated whether artificial superintelligence will emerge from a rapid, localized intelligence explosion or a gradual, decentralized accumulation across the global economy. While Yudkowsky argued that a small team could leverage hardware speed differentials to achieve a self-improving monopoly, Hanson countered that historical innovation patterns and the need for vast content would force AI development to remain integrated and shared. The post-debate audience vote shifted by seven voters to the "against" position, reflecting a narrow move toward Hanson's view that physical infrastructure and economic leakage prevent a single entity from instantly dominating the future.

  9. Y Combinator5h 9m

    Female Founders Conference 2017

    Avni Patel-Thompson, Emily Weiss, Laura Behrens Wu, Padmashree Warrior, Aileen Lee, Elizabeth Lyons, Vanessa Torridilla, Erica, Morgan de Bon, Diane Greene, Kirsty Nathoo, Carolyn Lebe, Anu Hariharan, Adora Chung, Jessica Livingston, Kat

    The Female Founders Conference brought together prominent industry leaders like Avital Lee, Kate Winslet, and Aileen Lee to analyze the nine distinct factors that differentiate successful startups from unicorns. Prominent founders from companies such as Poppy, Glossier, and NIO shared case studies on overcoming funding rejections, pivoting from failure, and building inclusive cultures within male-dominated sectors. The event concluded with YC partners debunking common myths about early-stage investment while emphasizing that persistent storytelling and rigorous data preparation are essential for women founders navigating systemic bias.

  10. Milken Institute1h 31m

    Agent of Change: The California-Israel Global Innovation Partnership

    Professor Itzik-Peterborg, Jay Keesling, Uri, Nati, Mark Gold, Yoram Cohen, Clive Kabat-Zinnick, David Blumberg

    The California-Israel Global Innovation Partnership, established via a 2014 agreement between Governor Jerry Brown and the Israeli Prime Minister, facilitates the cross-border transfer of expertise in water, energy, and biotechnology to help California transition from a startup-centric to a scale-up economy. Key figures including Prof. Jay Keasling, Prof. Itzik Peterborg, and executives from Netafim demonstrated how synthetic biology, digital health solutions, and precision irrigation can decouple agricultural output from resource constraints while addressing California's fragmented governance and water scarcity crises. This collaboration leverages financial protocols and bilateral fellowships to deploy proven Israeli technologies globally, aiming to create a carbon-negative bio-economy and implement real-time conservation incentives that bridge the gap between policy fragmentation and sustainable infrastructure.

  11. Milken Institute1h 36m

    Between Debt and the Devil: Money, Credit and Fixing Global Finance

    Adair Turner, Mike Clouden, Matt Miller, Lord Adair Turner

    Lord Adair Turner, former chairman of the UK Financial Services Authority, argues in *Between Debt and the Devil* that the global economic stagnation following the 2008 crisis stems from a failure to regulate private credit creation, which has shifted predominantly toward real estate speculation rather than business investment. He advocates for radical policy reforms including significantly higher bank capital requirements, strict lending limits on property markets, and the adoption of "overt money finance" to escape persistent low-growth equilibriums. Turner warns that without these structural adjustments and a reintegration of banking realities into macroeconomic models, advanced economies face continued inequality and the risk of social instability.

  12. Milken Institute1h 40m

    Asia Summit 2015 - AIIB and the Evolving Multilateral Lending Landscape

    Mike Milken, Lee Kuan Yew, Jin Li-chun, Tommy Koh, Jin Tong, Tadashi Maeda, Clive Kerner, Elena Okorochinko

    At a Milken Institute discussion, AIIB President-designate Jin Li-chun outlined the bank's lean, clean, and green operational framework designed to complement existing multilateral development banks in addressing a global infrastructure financing gap of $2 trillion annually. With 57 provisional founding members approved and a target to operationalize by year-end, the institution plans to leverage a 2.5 gearing ratio to reach $250 billion in lending capacity while offering flexible financing stages to bridge the $8 trillion Asian infrastructure demand projected for 2030. Although major economies like the United States and Japan remain cautious, stakeholders including rating agencies and the IFC view the AIIB as a strategic partner capable of enhancing credit quality and mobilizing private capital for sustainable development.

  13. Milken Institute1h 42m

    Asia Summit 2015 - Asia’s Future: Perspectives on Prospects and Challenges

    Wing, Kirk Wager, Mike Milken, Cesar, Purisima, Kevin Sneader, Jing Ulrich, Tim Cofer, Achal Agarwal, Sam Fisher, Chris Wei

    This event highlighted the United States' deepening strategic commitment to Southeast Asia, underpinned by a $220 billion cumulative investment in top ASEAN markets and projected to support a middle class growing from 525 million to 1.2 billion people by 2030. Key speakers detailed Indonesia's aggressive fiscal shifts, including a $32 billion subsidy cut and $22 billion infrastructure allocation, alongside the Philippines' demographic-driven growth fueled by its young, English-speaking workforce and expanding manufacturing sectors. Despite short-term currency volatility, the consensus among global corporations and government officials affirmed that Asia's unique blend of urbanization, digital innovation, and rising consumption will anchor the region as the primary engine of global economic expansion.

  14. Milken Institute1h 51m

    The Hot Zone Approach to Battling Gang Violence

    Connie Rice, Rev. Jeff Carr, Malcolm Klein, Charlie Beck, Ray Bercini, Father Gregory Boyle, Brian Center, Mike Clouden, Richard Sandler, Father Greg Boyle, Deputy Chief Charles Beck, Detective Ray Bersini, Deputy Mayor Jeff Carr

    Panelists led by Dr. Malcolm Klein and Los Angeles officials analyze the city's gang crisis, redefining the problem through five distinct gang types while critiquing the current over-reliance on individual-focused interventions. The discussion highlights a strategic shift toward evidence-based policies, such as the "Summer Night Lights" program and collaboration with organizations like Homeboy Industries, which emphasize community hope and structural economic reform over pure suppression. Despite reporting a drop in homicides from 350 to 167, experts warn that sustained political will and a $40 million investment are essential to address the underground economy and prevent a resurgence of violence.