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  1. Goldman Sachs23 min

    Dr. Siddhartha Mukherjee: Genetically Mapping the Future of Cancer

    Siddhartha Mukherjee, Richard Manley

    Dr. Siddharth Mukherjee outlines a paradigm shift in oncology where cancer is treated as a portfolio of distinct conditions managed through prevention, targeted early detection, and immunotherapy rather than a single curable entity. Advances in genetic engineering have moved the field from simply sequencing DNA to actively editing sequences, enabling cures for single-gene disorders and transforming historically lethal cancers like metastatic HER2-positive breast cancer into manageable chronic conditions. This revolution, driven by the ability to replace nucleotides and alter cellular environments, marks a historical transition comparable to the dawn of the computer age in its capacity to redefine human health.

  2. Goldman Sachs26 min

    Eric Schmidt: The Artificial Intelligence Revolution

    Eric Schmidt, Marty

    Goldman Sachs accelerates its cloud migration to leverage superior cybersecurity and specialized hardware for AI workloads, while the broader industry shifts toward data-driven deep learning that prioritizes scale over algorithmic provability. This transition enables "savant systems" in fields like healthcare and finance to automate trial-and-error processes, supported by a global talent market increasingly dominated by computer science graduates. Although these technologies promise to democratize expert-level capabilities through on-device and cloud computing, their adoption faces monetization hurdles and ongoing geopolitical competition, particularly from China.

  3. Goldman Sachs45 min

    Mary Barra on Driving Into the Future

    Mary Barra, Lloyd Blankfein

    GM Chairman and CEO Mary Barra is steering General Motors from a post-bankruptcy restructuring into a profitable leader focused on the strategic goals of zero crashes, zero emissions, and zero congestion. Under her leadership, the automaker prioritized product safety by adopting aerospace standards and launched a "speak up for safety" initiative following the 2014 ignition switch crisis, while simultaneously advancing autonomous vehicle technology through its subsidiary Cruise Automation. Beyond corporate strategy, Barra champions STEM education and female workforce retention through programs like "Take Two" and the Detroit Children's Fund to ensure diverse representation and community economic revitalization.

  4. Goldman Sachs21 min

    Diana B. Henriques: “A First-Class Catastrophe”: Lessons Learned from Black Monday

    Diana B. Henriques, Sharmin Mosavaramani

    This analysis juxtaposes the 1987 Black Monday crash, driven by opaque portfolio insurance strategies and fragmented regulation, with modern market vulnerabilities amplified by trillion-dollar asset managers and enduring regulatory silos. It further examines the psychological profile of Bernie Madoff, highlighting his pathological fear of failure and the spontaneous nature of his fraud's collapse, while detailing the HBO film "Wizard of Lies" production that secured Robert De Niro's casting through authentic in-prison dynamics. Together, these case studies illustrate how historical market failures and individual pathologies continue to inform contemporary debates on financial transparency and systemic risk.

  5. Goldman Sachs41 min

    Sir Richard Branson: Leading with Vision and Taking on Challenges

    Sir Richard Branson, David Solomon, John F.W. Rogers, Kevin McCarthy, Tyler Perry, Danny Meyer, Sarah Kauss, Wilbur L. Ross, Sara Blakely, Michael Bloomberg, Gina Raimondo, Rick Snyder, Marco Rubio, Lloyd Blankfein, Warren Buffett

    Richard Branson founded Virgin Group in the 1970s by launching Student magazine and Virgin Records despite operating within a state-dominated British economy, eventually pivoting from retail and aviation to space exploration and sustainable energy. Under his leadership, the conglomerate expanded into major ventures like Virgin Atlantic, Virgin Galactic, and Virgin Orbit while simultaneously addressing global challenges through Virgin Unite and geothermal initiatives in the Caribbean. Branson's strategy combines aggressive risk mitigation, such as lease clauses for aircraft returns, with a people-centric corporate culture that prioritizes employee well-being and entrepreneurial problem-solving.

  6. Goldman Sachs11 min

    Remarks by Senator Marco Rubio

    Marco Rubio, John F.W. Rogers, Kevin McCarthy, Tyler Perry, Danny Meyer, Sarah Kauss, Wilbur L. Ross, Sara Blakely, Michael Bloomberg, Gina Raimondo, Rick Snyder, Lloyd Blankfein, Richard Branson, Warren Buffett

    This analysis outlines a strategy to revitalize the American economy by dismantling regulatory barriers that favor large corporations while fostering grassroots entrepreneurship. It addresses the critical disconnect between traditional education and modern labor demands, advocating for expanded vocational training and targeted support for displaced workers aged 45 and older. Ultimately, the proposed framework envisions a prosperous future where the government facilitates a supportive ecosystem but allows the private sector to drive innovation and job creation.

  7. Goldman Sachs19 min

    Gov. Gina Raimondo (RI) and Gov. Rick Snyder (MI): Small Businesses Catalyzing the Future Economy

    Gina Raimondo, Rick Snyder, Dane Holmes, John F.W. Rogers, Kevin McCarthy, Tyler Perry, Danny Meyer, Sarah Kauss, Wilbur L. Ross, Sara Blakely, Michael Bloomberg, Marco Rubio, Lloyd Blankfein, Richard Branson, Warren Buffett

    Governors Gina Raimondo of Rhode Island and Gretchen Whitmer of Michigan implemented distinct fiscal and cultural reforms to elevate their states' business climates, with Michigan achieving the sixth-largest national job creation record and Rhode Island improving its unemployment tax ranking from 50th to 23rd. Both leaders prioritized workforce development through initiatives like mandatory computer science education and the "First Customer" program, which directly connected small suppliers with large enterprises to drive economic growth. Their shared strategy emphasizes immigrant entrepreneurship, digital literacy investments, and a governance model that treats government as a convener and connector to help small businesses scale from local operations to national impacts.

  8. Goldman Sachs10 min

    Remarks by The Honorable Wilbur L. Ross

    Wilbur L. Ross, John F.W. Rogers, Kevin McCarthy, Tyler Perry, Danny Meyer, Sarah Kauss, Sara Blakely, Michael Bloomberg, Gina Raimondo, Rick Snyder, Marco Rubio, Lloyd Blankfein, Richard Branson, Warren Buffett

    The event highlights the pivotal role of small and medium-sized enterprises in generating 63% of new jobs while detailing policy shifts that reduced regulatory burdens and altered tax structures for flow-through entities. Federal initiatives have intensified trade enforcement by 80% and deployed foreign commercial teams in 73 domestic and international locations to overcome export participation barriers that currently limit less than 3% of American businesses. These efforts, validated by case studies like Kaddis Enterprises' 400% growth, emphasize leveraging e-commerce and active marketing to facilitate business succession and global expansion.

  9. Goldman Sachs56 min

    Sarah Kauss: Starting Up and Going Global

    Sarah Kauss, Jo Natauri, John F.W. Rogers, Kevin McCarthy, Tyler Perry, Danny Meyer, Wilbur L. Ross, Sara Blakely, Michael Bloomberg, Gina Raimondo, Rick Snyder, Marco Rubio, Lloyd Blankfein, Richard Branson, Warren Buffett

    After gaining experience as a CPA during the dot-com era, Sarah Kaus founded Swell to combine fashion-forward hydration with a mission to reduce plastic waste. Under her leadership, the company expanded from a single boutique concept into a global brand stocked in 2,200 U.S. stores and major partners like Starbucks and Target. Kaus now guides a 100-person team with a philosophy that prioritizes financial self-sufficiency, rigorous quality control, and a culture that blends aggressive scaling with core environmental values.

  10. Goldman Sachs17 min

    Helping Small Businesses Grow: Views from 10,000 Small Businesses

    Steve Strongin, Amanda Hindlian, John F.W. Rogers, Kevin McCarthy, Tyler Perry, Danny Meyer, Sarah Kauss, Wilbur L. Ross, Sara Blakely, Michael Bloomberg, Gina Raimondo, Rick Snyder, Marco Rubio, Lloyd Blankfein, Richard Branson, Warren Buffett

    Over 100 small business owners across 18 states identified inconsistent regulations, labor shortages, and restricted capital access as critical barriers preventing economic growth and expansion. Participants detailed how bureaucratic complexity and frequent policy shifts force entrepreneurs to liquidate personal assets and divert resources from hiring to compliance, while survey data indicates that doubled financing availability would boost employment by 30%. To address these systemic issues, advocates propose establishing centralized credentialing systems and shifting toward cooperative compliance windows rather than punitive measures.

  11. Goldman Sachs15 min

    Rep. Kevin McCarthy: Standing Up for Small Businesses

    Kevin McCarthy, John F.W. Rogers, Tyler Perry, Danny Meyer, Sarah Kauss, Wilbur L. Ross, Sara Blakely, Michael Bloomberg, Gina Raimondo, Rick Snyder, Marco Rubio, Lloyd Blankfein, Richard Branson, Warren Buffett

    House Majority Leader Kevin McCarthy, a California Republican with deep roots in the state's energy and agricultural sectors, outlines his journey from early entrepreneurial ventures to crafting bipartisan legislation like the Jobs Act. He argues that small businesses are the nation's primary job creators and urges owners to build direct, sustained relationships with lawmakers to overcome capital and training hurdles. Drawing on historical symbolism from the Gettysburg Address and Washington Crossing the Delaware, McCarthy concludes by calling for cross-party collaboration to address long-term challenges and forge a more perfect union.

  12. Goldman Sachs13 min

    John F.W. Rogers: Opening Session Remarks

    John F.W. Rogers, Kevin McCarthy, Tyler Perry, Danny Meyer, Sarah Kauss, Wilbur L. Ross, Sara Blakely, Michael Bloomberg, Gina Raimondo, Rick Snyder, Marco Rubio, Lloyd Blankfein, Richard Branson, Warren Buffett

    Goldman Sachs is convening 10,000 Small Business Program alumni, including 2,200 current participants, to address critical operational hurdles such as hiring and financing while leveraging the sector's role in employing 60 million Americans. The summit features a strategic "Hill Day" that mobilizes this diverse network to meet with elected officials across all 50 states and nearly all congressional districts to advocate for legislative relief. By uniting these resource-constrained firms, the event aims to bridge the gap between current business expectations and future capabilities through actionable insights and direct policy engagement.

  13. Goldman Sachs16 min

    Boyan Slat: Combatting Plastic Pollution in the World’s Oceans

    Boyan Slat, Cliff Marriott

    Founder and CEO Boyan Slat's organization is advancing a fleet of 60 passive, U-shaped floating barriers designed to remove 50% of the Great Pacific Garbage Patch within five years by leveraging natural ocean currents rather than traditional active fishing methods. Following a rigorous development cycle marked by early prototype failures and a $40 million capital raise, the system has evolved from inflatable chambers to solid pipe structures and is currently undergoing assembly at a facility near San Francisco for a targeted July launch. This initiative addresses an annual economic cost of $13 billion and a threat to 800 marine species by simultaneously targeting legacy accumulation in the Pacific and intercepting the roughly 2 million tons of river-borne plastic entering the ocean each year.

  14. Goldman Sachs25 min

    Amy Chua: Political Tribalism and American Foreign Policy

    Amy Chua, Rob Mass

    Yale Law professor Amy Chua analyzes global and domestic group dynamics through her concept of the "supergroup," contrasting the United States' unique ability to balance national unity with subgroup flourishing against the assimilationist models of France and China. She attributes rising U.S. political polarization to demographic shifts that have created defensive tribalism between coastal elites and the white majority, a division she attributes to a rhetorical shift from universalism to identity politics. Chua concludes by proposing practical remedies such as a national service "gap year" to foster intergroup interaction and arguing that allowing controversial speech prevents extremism from festering in epistemological silos.

  15. Goldman Sachs14 min

    Talks at GS – Magic Johnson On “Over-Delivering” On And Off The Court

    Magic Johnson, Earvin "Magic" Johnson

    Magic Johnson transitioned from leading Michigan State to an NCAA title and cultivating a legendary rivalry with Larry Bird in the NBA to a distinguished business career driven by strategic mentorship and deep market insight. Following his 1991 HIV diagnosis, he credits his 26-year survival to a regimen of mental resilience, physical training, and medication adherence, while leveraging his public platform to launch ventures like Magic Johnson Theaters and invest in the Los Angeles Sparks and Dodgers. Johnson now focuses his legacy on creating economic opportunities for people of color in urban America, prioritizing societal impact over personal wealth accumulation.