Latest Interviews
Showing 286–300 of 6,329 interview transcripts.
Clear all filters- Y Combinator32 min
Alexandr Wang: “This is a Once-in-a-Civilization Opportunity”
Alexander Wang discusses his journey from founding Scale AI to leading Meta's Frontier Lab, where he is developing the Muse Spark model to deliver frontier-level AI capabilities at a fraction of the cost. He argues that the immediate future of the industry will be defined by agentic looping and the orchestration of autonomous agents rather than raw model size, predicting a massive expansion in global GDP driven by these technologies. Wang concludes by advising founders to build independent convictions based on first principles while emphasizing that systematic thinking and vision are becoming the scarce resources in an era of abundant computational intelligence.
- Goldman Sachs24 min
Arun Gupta on Bringing Silicon Valley’s Spirit to Public Service
Noble Reach establishes a "community of dual citizens" by placing private-sector innovators into 2-3 year federal rotations to address critical generational talent gaps within US government technology sectors. Supported by strategic partners like Goldman Sachs, the organization deploys scholars to solve complex problems in state, local, and federal agencies while leveraging bipartisan mentorship and technical training to decouple public service from political ideology. This "residency match" model aims to foster long-term career resilience and global competitiveness against adversaries practicing civil-military fusion, ultimately validating public service as both altruistic and professionally advantageous.
Lumentum CEO: How Lasers Are Transforming AI Data Centers
Michael Hurlston, Tony Kim, Molly O'Shea
Under CEO Michael Hurlston, Lumentum has transformed from a diversified manufacturer into a pure-play data center optical leader, tripling revenue and driving its stock price up to 12-fold by capitalizing on the industry's rapid shift from copper to fiber connectivity. This transition, necessitated by the physical limitations of copper in high-speed environments, is straining the specialized Indium Phosphide supply chain due to long lead times for dedicated fabrication facilities. Facing tens of millions in new hyperscaler orders, the company is simultaneously expanding into space-based internet infrastructure and navigating geopolitical dynamics that favor U.S. domestic suppliers over Chinese competitors.
- All-In Podcast1h 9m
The Robot Episode: Four Leaders on What's Coming
Dr. Péter Fankhauser, Bernt Børnich, Amanda McMaster, Jonathan Hurst, J-Cal
Leading robotics firms including Anybotics, Boston Dynamics, and Agility Robotics have collectively deployed over 1,000 specialized units globally to replace humans in hazardous industrial settings, prioritizing data sovereignty and ISO cybersecurity standards to avoid reliance on Chinese hardware. These companies are currently transitioning from pure detection to scalable autonomy through platform-based ecosystems and cost reductions, with humanoids targeting a $40,000 price point and quadrupeds enabling continuous 24-hour monitoring in extreme environments. While immediate returns focus on safety and leak prevention, the industry anticipates a hard take-off in manufacturing capabilities within a decade as foundational AI models enable complex, multi-arm manipulation without physical safety barriers.
- Sequoia Capital49 min
Building the Automated AGI Lab: Core Automation's Jerry Tworek and Rohan Anil
Jerry Tworek, Rohan Anil, Sonya Huang, Pat Grady
Founded by Jerry Liu and Rohan Ramachandran, Core Automation aims to replace static Transformer models with a new class of AI systems capable of continual, test-time learning. The organization is building an automated research lab designed to overcome architectural bottlenecks by developing hardware-efficient kernels and enabling models to autonomously optimize their own code. Success for the venture is defined by the system's ability to self-improve without human intervention, effectively extending the team's operations while bypassing the diminishing returns of current scaling methods.
- The Economist8 min
Why knowing the future doesn't always help predict markets | The Economist
Elm Wealth's study compared the performance of laypeople, artificial intelligence models, and professional macro traders by simulating 15 days of trading with perfect future news on historical market data. While professionals doubled their starting capital by dynamically adjusting leverage based on confidence, average human and AI participants barely broke even or lost their entire stake due to poor bet sizing. The findings highlight that successful investing relies more on capital allocation and risk management than on superior directional prediction accuracy.
- Goldman Sachs20 min
What the Surge in IPOs Means for Investors
Jay Ritter, Owen Lamont, Allison Nathan
Goldman Sachs Research reports that the U.S. IPO market reached record issuance levels in 2026 while maintaining average valuations that distinguish current activity from historical speculative bubbles. Analyst Jay Ritter and Owen Lamont offer diverging perspectives on this surge, with Ritter arguing deep capital markets can absorb new supply without overvaluation, whereas Lamont warns that a massive wave of issuance signals the early stages of a potential bubble. Both experts agree that structural shifts, including expanded private markets and industry consolidation, have permanently reduced the average annual IPO count to roughly 100, fundamentally altering the relationship between new listings and future market returns.
- 80,000 Hours2h 9m
We Read 100 Self-Help Books So You Don't Have To.
Luisa Rodriguez, Spencer Greenberg
In a survey of 60 to 110 effective altruists and high-impact workers, Spencer Greenberg and the 80,000 Hours team found that while few suffer from clinical disorders, most experience significant psychological challenges that hinder productivity. Greenberg outlines maladaptive behaviors like constant threat monitoring and identifies strategies such as "clean fuel" motivation, the Magic Dial exercise, and acceptance-based planning to sustain long-term effectiveness. The analysis concludes that prioritizing psychological sustainability through intrinsic values and preventative self-care is a strategic necessity rather than a selfish distraction for practitioners in existential risk and related fields.
- a16z42 min
Fei-Fei Li is Solving the Hardest Problem in Robotics | World Labs with a16z
Fei-Fei Li, Martin Casado, Yunzhu Li
World Labs is acquiring Cynics to fuse its generative "Marble" spatial intelligence model with advanced robotics simulation, creating a scalable pipeline that replaces dangerous physical data collection with reliable digital environments. Led by CEO Fei-Fei Li alongside Cynics' leadership team, the merged entity will deploy this technology in semi-structured industrial settings to train multimodal "omni models" capable of counterfactual reasoning and efficient robot control. This strategic integration aims to validate a robust "real-to-sim-to-real" framework with early commercial customers before addressing the complexities of unstructured human environments.
- Y Combinator39 min
Sam Altman: "Never a Better Time to Do a Startup"
Sam Altman, Paul Graham, Garry Tan
Sam Altman and Y Combinator highlight an exponential shift in startup capabilities where coding agents reduce development time to mere seconds while hard tech representation in the portfolio surges to 25%. The organization positions itself as a decentralizing force to prevent single-entity control of AI power, explicitly rejecting the "live action role play" mindset in favor of heretical, high-conviction building. Altman warns of safety risks regarding surveillance and model concentration but maintains that widespread founder agency and distributed innovation will ultimately prevent economic collapse or catastrophic safety incidents.
- Bank of America14 min
Signals & Noise: Bubble Building in the Age of AI
Ben Bowler, Arjun Goyal, Benjamin Bowler
Bank of America Global Research identifies a prevailing "bubble era" driven by reflexive feedback loops where rising prices and volatility reinforce one another across asset classes like AI, tech, and cryptocurrencies. The firm's proprietary Bubble Risk Indicator (BRI) quantifies this instability using historical price data, successfully flagging recent pullbacks in Korean equities and vulnerable sectors such as cybersecurity and semiconductors. Strategic guidance suggests investors prioritize monitoring this metric over traditional valuations to navigate an environment characterized by higher volatility, larger drawdowns, and rapid snapbacks without an immediate terminal crash.
- Goldman Sachs17 min
Jon Winkelried on Lessons from Goldman Sachs and TPG’s Next Chapter
Jon Winkelried, Matt McClure, John Winkle-Reed
John Winkle-Reed, who rose from a 1981 Goldman Sachs intern to co-president before retiring in 2009, applied his leadership philosophy of active listening and decision transparency to transform TPG from a $64 billion founder-led buyout firm into a $310 billion diversified public alternative asset manager. His strategic shift from a siloed structure to a unified "one firm" orientation overcame significant internal resistance, enabling the 2022 public listing and major acquisitions like Angela Gordon in 2023. Currently serving as sole CEO since 2021, Winkle-Reed has integrated artificial intelligence as a central growth driver while steering the organization's geographic and operational evolution from a San Francisco-centric model to a global enterprise with its largest workforce in New York.
Will Open-Source Threaten Anthropic's Business & Do Margins Matter in a World of AI | Matt Murphy
Menlo Partners led Anthropic's initial $10 million seed round and subsequently deployed a $500 million Special Purpose Vehicle to secure a leading position in the AI sector, prioritizing access to high-conviction outliers over traditional ownership mandates. This strategy supports a broader barbell approach where the firm targets hyper-growth seed companies like Lovable and OpenRouter while maintaining large growth positions, effectively bypassing the crowded Series A stage. By focusing on technical depth, operational efficiency, and global talent hubs, Menlo aims to maximize upside in a market shifting toward "winner-take-all" dynamics despite high valuations.
Inside the Fastest-Growing Category in AI: Scott Wu, CEO of $26B Cognition
Cognition has secured a $26 billion valuation and $500 million in revenue by deploying its autonomous AI engineer, Devon, to solve complex engineering tasks for major clients like Goldman Sachs and NASA. The company recently consolidated its operations by acquiring the 200-person Windsurf IDE team, creating a unified hybrid environment where local coding and remote cloud agents collaborate seamlessly. Founder Scott Wu emphasizes an immediate "abundance era" of software mass-creation over human obsolescence, while maintaining model neutrality and refusing integration into larger tech conglomerates as the firm prepares to demonstrate its self-driving software capabilities at the upcoming RAISE AI summit in Paris.
- The Diary Of A CEO2h 0m
Vitamin D Expert: The Supplement World Is Giving The WRONG Advice!
Dr. Stasha Gomenak challenges conventional medical approaches by asserting that widespread sleep disorders and chronic conditions stem from biochemical deficiencies, specifically Vitamin D and B vitamin deficits resulting from indoor lifestyles that limit sunlight exposure. Her clinical protocol prioritizes maintaining serum Vitamin D levels above 60 ng/mL and administering high-dose B-complex supplementation to restore acetylcholine production and gut microbiome health, effectively treating patients with severe insomnia, depression, and neurological symptoms often misdiagnosed as anatomical or purely behavioral issues. Supported by case studies of individuals recovering from conditions ranging from narcolepsy to postpartum depression, this framework proposes a shift from symptom suppression to fundamental biological repair through personalized nutrient dosing and sunlight interaction.