Latest Interviews

Building the Future of Health Data

Cynthia Grossman

Faster Cures, a center of the Milken Institute, launched a strategic initiative to accelerate medical advancement by empowering patients through the "Health Data Basics" framework and a new community of early adopters. The program aims to resolve systemic trust deficits by co-creating ethical standards for accessible, secure health data that integrates genomic, clinical, and daily digital metrics to improve outcomes. Following a call to action for stakeholders to join this movement, the organization asserts that leveraging data from patients' everyday environments is essential for predicting disease trajectories and developing targeted therapies.

Discover Hyderabad

Jonty, Usha, Saurabh Chatterjee, Srinivas Kolipara, JNT Raj Gopalan

Hyderabad has evolved from a historic center of diamond and pearl wealth into a vibrant modern metropolis anchored by T-Hub's rapid startup growth and Google's expanding campus in the Cyberabad district. The city's unique identity seamlessly blends this technological boom with deep cultural traditions, ranging from the ancient Charminar markets and royal Taj Falaknuma Palace to innovative experiences like Ayurvedic cocktails and local flower trade photography. Visitors engage with this duality through immersive activities such as traditional haggling, home-style cooking classes, and participation in religious festivals that welcome strangers into local celebrations.

Understanding SAFEs and Priced Equity Rounds by Kirsty Nathoo

Kirsty Nathoo

This presentation clarifies critical capitalization mechanics for founders by advocating for the mandatory use of post-money SAFEs to ensure transparent ownership tracking and simplify dilution calculations. It details how cumulative equity issuance from SAFE conversions, employee option pools, and priced rounds like Series A significantly impacts founder control, as demonstrated by a scenario where ownership drops from 100% to 51.5%. The analysis further warns against over-optimizing early valuation caps and mixing instrument types, emphasizing that proactive math is essential to prevent founders from retaining negligible equity after financing.

How MDMA is being used to treat PTSD

Rick Doblin, John Lubecki

With standard treatments effective in only 20% of cases, researchers led by Rick Doblin are pursuing FDA approval for MDMA-assisted therapy after trials showed over 60% of participants no longer met PTSD criteria. The non-profit-funded study utilizes a regimen of three drug sessions paired with psychotherapy to allow veterans like John Lubecki to process trauma without fear, a potential breakthrough for the 8 million Americans suffering from the disorder. Because the drug cannot be patented, this initiative by a small organization aims to transform the illicit substance into a regulated medicine that addresses a public health crisis costing the Department of Veterans Affairs $400 million annually.

The data revolution: privacy, politics and predictive policing

Dr Tom Devlin, Trump, Nick Bowers, Carol Reed, Hal Hodson, David Carroll, Mark Zuckerberg, Jamie Garcia, Hamid Khan, Sergeant David Rich, Anthony, Leo Hu

The event examines how the exponential growth of data generation is transforming healthcare through AI tools like Viz.ai while simultaneously enabling invasive surveillance in consumer marketing, law enforcement, and state control systems. Key case studies include the medical success of stroke detection algorithms, the electoral manipulation via Cambridge Analytica's unauthorized data harvesting, and the controversial implementation of China's Social Credit System. Furthermore, the discussion highlights significant ethical conflicts surrounding predictive policing biases in Los Angeles and the ongoing legal battles to ensure transparency in how personal data is collected and utilized by governments and corporations.

Gustaf Alstromer - How to Get Users and Grow

Gustaf Alstromer

This Y Combinator session details critical administrative adjustments for the startup course while establishing a rigorous framework for achieving product-market fit through specific value metrics and retention benchmarks. Speakers analyze historical growth patterns from Airbnb and Facebook to illustrate how deliberate engineering strategies, data-driven experimentation, and performance marketing replace intuition as companies scale. The discussion concludes by emphasizing that sustainable growth requires positive unit economics, disciplined A/B testing cultures, and a clear distinction between early-stage validation and mature paid acquisition channels.

Reshma Shetty, Founder of Ginkgo Bioworks at the Female Founders Conference

Reshma Shetty

Ginkgo Bioworks, a Boston-based female-founded unicorn, leverages the digital nature of DNA to program organisms with sub-nanometer precision while advising founders to raise substantial capital only under strict fiscal discipline to avoid the pitfalls of organizational bloat. The company distinguishes its scaling strategy by enforcing efficiency through a "Scrooge McDuck" leadership role and a "Mission to Metrics" framework that explicitly links its core goal of making biology easier to engineer with quantitative measures like output per employee. This approach allows Ginkgo to decouple commercial growth from headcount expansion, thereby mitigating non-linear interpersonal conflicts and sustaining a competitive advantage despite rapid organizational expansion.

The Global M&A Outlook

Dana Mattioli, Leon Kalvaria, Navid Mahmoodzadegan, James Sprayregen, Chris Stadler, John Waldron

With year-to-date M&A activity reaching a record $1.6 trillion driven by tax reforms, activist pressure, and technological disruption, corporations are increasingly pursuing de-conglomeration and offshore consolidation despite regulatory uncertainties. Industry leaders are prioritizing cultural due diligence and capital allocation efficiency to navigate a landscape defined by aggressive private equity competition and a shift toward relational retail models. While panelists forecast a robust remainder of the year fueled by strong valuations and low rates, they caution that geopolitical shocks and potential regulatory blockages could disrupt the current market euphoria.

The Next Urban Revolution: Reimagining Cities for an Aging Population

Nora Super, James Anderson, Julián Castro, Thomas Lantzsch, Jaana Remes, Jim Anderson, Tom Lanch, Jana, David Rockefeller Jr., Quinn, Yana Shih, Tom Hanksman Jr.

Demographic shifts project a global surge in the senior population that is reshaping urban dynamics, housing models, and consumption patterns while exposing gaps in economic security for aging communities. Cities like Tokyo, Los Angeles, and Singapore are responding with innovative multigenerational housing, autonomous mobility solutions, and talent recruitment programs to maintain independence and address infrastructure needs. Experts recommend a strategic pivot from viewing aging as a vulnerability to an asset-based approach that leverages the continued productivity of retirees through targeted policy, public-private innovation, and data-driven resource allocation.

Can a cure for diabetes be found through surgery?

Peter Hansel, Professor Francesco Rubino

Despite the global surge of Type 2 diabetes affecting one in ten people by 2040, Professor Francesco Rubino's research demonstrates that gastric bypass surgery can induce immediate remission by correcting duodenal hormone signaling rather than relying solely on weight loss. While only 0.1% to 1% of eligible patients currently access this life-saving procedure, Rubino is leading clinical trials on non-invasive alternatives and driving updates to international guidelines that recognize surgery as a primary treatment option. This work provides critical biological evidence that challenges the "lifestyle disease" narrative, offering a pathway for future pharmaceutical cures to address the epidemic without requiring invasive intervention.

El Salvador's violent gang members are finding God in prison

Wilfredo Gómez

Following his deportation from the U.S. to El Salvador in 1996, former 18th Street gang member Wilfredo Gómez founded a Christian prison ministry that expanded to house over 900 inmates within a violent, overcrowded system. While the program offered temporary sanctuary and social mobility through a segregated religious zone, its long-term success remains limited as societal stigma and a lack of employment opportunities prevent most converts from maintaining their faith outside prison. Ultimately, the initiative highlights a critical gap between individual rehabilitation within the jail and the structural barriers preventing former gang members from achieving permanent reintegration into Salvadoran society.

Ireland: divided by abortion

On May 25th, Irish voters will decide whether to repeal the Eighth Amendment, a 1983 constitutional provision that currently bans abortion except when the mother's life is at risk. Prime Minister Leo Varadkar and pro-choice advocates, citing the unsafe nature of current cross-border travel and shifting public sentiment, support legalization up to the twelfth week, while pro-life campaigners warn that removing the amendment permanently prevents future legislative control. With recent polls showing the electorate is nearly evenly split, this referendum represents a definitive test of Ireland's transition toward a secular society or its retention of traditional conservative values.

Exploring and protecting the Antarctic

Dr. Susan Lockhart, John Hosevar

Dr. Susan Lockhart and co-pilot John Hosevar achieved the first human submersion in the Antarctic Weddell Sea, where their observations of fragile ecosystems like deep-sea sponges contradicted assumptions that the deep seabed was barren. Their data revealing the extreme vulnerability of these communities to industrial fishing underscores the urgent need to expand global ocean protection beyond the current 3.7%. This evidence is now poised for a critical Antarctic Commission vote in July 2018, where unanimous consensus from member states could establish the region as the world's largest no-fishing zone despite historical delays in such approvals.

Remarks by Michael Bloomberg

Michael Bloomberg, John F.W. Rogers, Kevin McCarthy, Tyler Perry, Danny Meyer, Sarah Kauss, Wilbur L. Ross, Sara Blakely, Gina Raimondo, Rick Snyder, Marco Rubio, Lloyd Blankfein, Richard Branson, Warren Buffett

Former New York City Mayor Mike Bloomberg chronicled the analog origins of his firm and argued that the American "ethic of trying again" remains the primary driver of economic resilience. He sharply criticized current U.S. immigration and regulatory policies for threatening the small business sector, which historically serves as the incubator for future large-scale corporations and employs millions of immigrant-owned enterprises. Bloomberg concluded with a direct call to action, urging entrepreneurs to aggressively lobby elected officials for open immigration and reduced red tape to ensure sustained economic growth.

Remarks by The Honorable Wilbur L. Ross

Wilbur L. Ross, John F.W. Rogers, Kevin McCarthy, Tyler Perry, Danny Meyer, Sarah Kauss, Sara Blakely, Michael Bloomberg, Gina Raimondo, Rick Snyder, Marco Rubio, Lloyd Blankfein, Richard Branson, Warren Buffett

The event highlights the pivotal role of small and medium-sized enterprises in generating 63% of new jobs while detailing policy shifts that reduced regulatory burdens and altered tax structures for flow-through entities. Federal initiatives have intensified trade enforcement by 80% and deployed foreign commercial teams in 73 domestic and international locations to overcome export participation barriers that currently limit less than 3% of American businesses. These efforts, validated by case studies like Kaddis Enterprises' 400% growth, emphasize leveraging e-commerce and active marketing to facilitate business succession and global expansion.