Latest Interviews
Showing 31–45 of 131 transcripts.
Clear all filtersInside Harvey AI: CEO Winston Weinberg on How a 4-Year-Old Company Is Taking on the Foundation Labs
Winston Weinberg, Molly O'Shea
Harvey AI has scaled to nearly $300 million in ARR and over 2,000 enterprise clients by migrating to cloud agents and deploying specialized legal models that outperform general frontier AI. CEO Sam Saltman drives a culture of rapid reinvention and meritocracy, where over 200 legal professionals transition into product and engineering roles to build vertical-specific solutions for high-growth sectors like finance and pharmaceuticals. The company differentiates itself from traditional legal tech and generic AI labs by prioritizing granular ROI proof per token and rejecting legacy technology acquisitions in favor of acquiring high-performing teams to fuel its current 12-to-13 trillion token monthly usage projections.
- Y Combinator17 min
Conductor CEO Charlie Holtz Walks Us Through His AI Coding Setup
Charlie, co-founder of Conductor, leads a team developing a macOS application that orchestrates multiple coding agents to generate software primarily in TypeScript and Rust. The platform enforces a strict non-terminal workflow where AI handles code generation while humans intervene only through specific review modes to maintain quality and prevent error cycles. With a strategic focus on high-efficiency model selection and a future roadmap emphasizing malleable, modifiable agents, Conductor positions itself as a tool that shifts software value from code itself to human-authored prompts and descriptions.
Tom Mueller: SpaceX's #1 Employee Built the Merlin Engine. Now He's Building Impulse Space
Former SpaceX founding employee Tom Mueller founded Impulse Space to revolutionize intra-orbital transport with its fleet of advanced spacecraft, including the orbital transfer vehicle Mira and the heavy-lift Helios. The company leverages proprietary Nova Light alloy and additive manufacturing to produce the Deneb hydrocarbon engine and lightweight composite tanks, achieving performance metrics that could significantly boost payload delivery to the Moon and Mars. Currently advancing lunar infrastructure efforts through successful rendezvous tests and an active lander contract bid, Impulse Space combines in-house manufacturing with AI-driven design to support a future lunar economy.
Inside PsiQuantum: The Photonics Chip Never Seen Before
Leveraging Molecular Beam Epitaxy within a Class 1,000 cleanroom, engineers fabricate high-precision Barium Titanate on Strontium Titanate films atop 300mm silicon wafers to support single-photon quantum computing architectures. The ultra-high vacuum process employs rigorous environmental controls and automated transfer systems to ensure crystalline integrity while facilitating immediate integration into high-volume manufacturing lines with partners like GlobalFoundries. Ongoing characterization using RHEED and optical interference validates these substrates for future dual utility as qubits or storage vectors within scalable quantum systems.
- 80,000 Hours36 min
Will AI cause mass unemployment? Maybe not.
Amid widespread fear of AI-driven job displacement, the event analyzes historical automation trends to reveal that wages may rise significantly until 2037 before facing a decline if full task automation is achieved without human oversight. Experts identify four categories of skills likely to increase in value, including complex physical tasks, AI deployment capabilities, and roles producing scalable goods, while warning against exclusive specialization in routine knowledge work. The presentation concludes by advising professionals to cultivate transferable leadership and technical abilities that bridge human decision-making with AI efficiency to navigate a shifting labor market.
- Sequoia Capital25 min
Neuralink's DJ Seo: Inside the Race to Connect Brains and AI
DJ Seo, Shaun Maguire, Sean McGuire
Neuralink is advancing its brain-computer interface technology through the deployment of two therapeutic products, Telepathy and Blindsight, to restore motor function and vision for patients with conditions like ALS and total blindness. The company has implanted its devices in over 20 human participants and reports successful trials where users regained computer control or visual perception, supported by a strategy of vertical integration and an "all-green light" engineering framework. Founder J.D. McGuire envisions these medical breakthroughs as a precursor to creating an "exocortex" that merges human intent with AI, pending regulatory approval for broader non-medical augmentation.
- Jane Street16 min
Dwarkesh Goes Inside Jane Street's Latest AI Data Center
Dwarkesh, Ron Minsky, Daniel Pontecorvo, Mark Mirchandani
Jane Street transformed a Texas data center into a high-density liquid-cooled facility housing 4,032 GPUs to execute large language model training and custom trading architectures. The retrofit replaces legacy air-cooling with an 18°C fluid distribution system that manages 140 kW per cabinet while utilizing proprietary software to dynamically redistribute power and prevent breaker trips during peak loads. Engineering safeguards now focus on mitigating new liquid-cooling risks like biological growth and leaks, enabling sub-100-nanosecond latency required for modern algorithmic trading compared to the millisecond scales of its historical "Hive" cluster.
- Sequoia Capital11 min
AI That Designs Its Own Chips: Ricursive's Anna Goldie and Azalia Mirhoseini
Anna Goldie, Azalia Mirhoseini
Founded by former leaders from Google Brain, Anthropic, and DeepMind, Recursive Intelligence has deployed its AlphaChip technology to optimize billions of transistors for Google's TPU and Axion lines while adopting by MediaTek. The company currently accelerates chip design by running static timing analysis 1,000 times faster than commercial tools, enabling AI agents to generate curved, organic layouts that reduce wire lengths and cut annual design cycles from months to days. Looking ahead, Recursive plans to democratize custom silicon through a platform model that delivers fabrication-ready layouts without in-house teams, ultimately aiming to vertically integrate design and fabrication into a self-reinforcing loop for frontier AI systems.
Figure's First Full HQ Tour: From the Lab to the Factory Floor
Brett Adcock, Molly O'Shea, Moritz
Figure AI is a Bay Area-based pure-play manufacturer with a 500-person engineering workforce deploying its flagship Figure 3 humanoid robot, which operates autonomously using the locally running Helix AI policy. The company has achieved record production output at its "Baku" facility while reducing unit costs by 90% compared to previous models, enabling deployments in settings ranging from the White House to BMW automotive assembly lines. Looking ahead, Figure aims to commercialize a lease-based home model and advance toward its "iPhone moment" with the upcoming Figure 4, which targets radical improvements in cost and usability while pursuing physical interaction-based AGI.
Skydio HQ Tour: The $3.5B Bet on American Drone Manufacturing with CEO Adam Bry
An autonomous drone network delivers 24/7 public safety operations by deploying units from charging docks to locate missing persons, track suspects, and inspect infrastructure without human pilots. The system utilizes Beyond Visual Line of Sight waivers and Pathfinder AI to execute complex missions across diverse hardware, ranging from the indoor R10 tactical unit to the high-speed F10 fixed-wing prototype. Through a transparency portal and continuous real-world stress testing, the company has integrated these force-multiplier tools into law enforcement culture while scaling production for imminent general availability.
- The Economist9 min
AI has got better at hacking—how big a risk is it?
Anthropic withheld its latest model, Mythos, from public release after it demonstrated the ability to autonomously identify and exploit critical software vulnerabilities, such as a 27-year-old OpenBSD flaw, with minimal human intervention. This decision follows evidence that AI scaling laws now enable automated systems to accelerate the vulnerability exploitation cycle from years to mere hours, drastically outpacing current defensive capabilities. While Anthropic employed responsible disclosure by patching the specific bug before sharing details, the incident highlights a growing risk that open-source models will soon democratize high-level cyberattacks.
- Y Combinator22 min
How to Make Claude Code Your AI Engineering Team
Gary Tan, President and CEO of Y Combinator, has launched GStack, an open-source framework that restructures AI coding assistants into specialized engineering teams to overcome current limitations in model scaffolding. The system utilizes skills like Adversarial Review and the Office Hours query to automatically identify design flaws, generate multiple UI variants, and process hundreds of daily pull requests without traditional to-do lists. With over 70,000 GitHub stars, GStack shifts developer focus from manual coding to strategic oversight, enabling the management of parallel AI sessions to accelerate software factory operations from ideation to production.
- Y Combinator31 min
This Startup Catches Fraud at Scale
Jared Friedman, Karine Mellata
Variance has officially exited stealth mode following a $21 million Series A round to commercialize AI agents that automate trust and safety infrastructure for Fortune 500 clients like GoFundMe and IAC. Founded by ex-Apple engineers Karine and Michael, the 12-person team leverages a unique "agentic" architecture to solve complex unstructured data problems in fraud detection and compliance without manual rule updates. Despite a 2024 leadership injury that threatened operations, the company is scaling its full-stack decisioning platform to replace traditional human review workflows with adaptive, self-healing systems designed to trace sophisticated abuse graphs.
- a16z47 min
The New Media Playbook with Marc Andreessen & Ben Horowitz
Marc Andreessen, Ben Horowitz, Erik Torenberg
The firm fundamentally redefines media strategy by replacing the defensive posture of traditional journalism with an offense-oriented approach that prioritizes speed, founder-led personal branding, and content saturation to control narratives within a 24-hour cycle. By treating viral posts as the primary medium and leveraging an OODA loop of rapid observation and action, the organization enables portfolio companies to generate immediate engagement through direct CEO communication rather than abstract corporate messaging. This ecosystem now functions as a comprehensive launch service and talent development pipeline, positioning the firm as the definitive standard for "New Media" roles while advising leaders to embrace controversy as a necessary signal of power in a landscape where old media acts only as a lagging indicator.
- Y Combinator40 min
AI Is Unlocking Millions Of New Builders
Led by twins Mukund and Madhav Jar, Emergent is a YC Summer 2024-funded platform that empowers non-technical users to generate production-ready software through AI agents, having already built seven million apps across 190 countries. The company differentiates itself by utilizing a custom Kubernetes infrastructure and multi-agent architecture to solve the "it works on my machine" problem, while its core team achieved top-tier status on the SWE-bench benchmark within two months. By pivoting from automated testing to full-stack application development, Emergent has democratized software creation, allowing solopreneurs to launch functional products for thousands of dollars instead of the traditional half-million-dollar cost.