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  1. Milken Institute1h 1m

    Institutional Investors: Managing for the Long Term

    Christopher Ailman, Jerry Albright, Jingdong Hua, Kim Lew, Amy McGarrity, Hiromichi Mizuno, Chris Ailman

    Five CIOs managing over $1.6 trillion across diverse institutional structures, from Carnegie's $3.5 billion foundation to Japan's $1.6 trillion GPIF, convened to analyze how unique liability profiles and time horizons dictate long-term investment strategies. The panelists detailed operational shifts toward sustainable "universal ownership," highlighted the World Bank's leadership in green bond markets, and emphasized the critical need to align staff incentives and board education with multi-decade fiduciary duties rather than short-term volatility. Despite diverging views on the necessity of formal ESG mandates and the degree of market influence asset owners should wield, the group collectively identified global development gaps and market structure fragilities as paramount risks requiring coordinated action.

  2. The Economist7 min

    Who will challenge Donald Trump in 2020?

    Donald Trump, John Prideaux

    The 2020 Democratic primary acts as a decisive ideological referendum that will narrow a large field to a nominee by September. Vice President Joe Biden leads as the moderate frontrunner focused on electability, while Senator Bernie Sanders and Senator Elizabeth Warren compete for progressive voters with distinct policy platforms. Secondary contenders including Mayor Pete Buttigieg, Senator Kamala Harris, Senator Amy Klobuchar, and Senator Cory Booker seek to capitalize on the race's central tension between generational change and broad electoral appeal.

  3. Milken Institute1h 2m

    Outsmarting Superbugs: What Are the Alternatives?

    Margaret Hamburg, Matthew Hepburn, Peter Jackson, Nancy Knight, Jeanette Mucha, Peter Piot, Peggy Hamburg, David Wallace, Lance Price

    Global leaders and organizations including the WHO, CDC, and the U.K. government are coordinating a multi-faceted response to antimicrobial resistance, which threatens to cause 10 million annual deaths by 2050 and mimic the 2008 financial crisis through massive economic losses. Innovative initiatives such as the CDC's AMR Challenge, Carb-X's $80 million funding for 40 development projects, and the U.K.'s "pull incentive" trial aim to revitalize the antibiotic pipeline by supporting SMEs and rewarding disease prevention rather than sales volume. Despite these advances, experts warn that rigid intellectual property laws, inadequate wastewater treatment, and capital gaps in microbiome startups hinder the deployment of new therapies needed to combat untreatable superbugs like drug-resistant tuberculosis.

  4. Goldman Sachs16 min

    Goldman Sachs at 150: Part 9 – Crisis (2008)

    Lloyd Blankfein, Marty

    In June 2006, Lloyd Blankfein succeeded Hank Paulson as CEO of Goldman Sachs, guiding the firm through the unfolding U.S. housing bubble and the subsequent 2008 financial crisis. While the collapse triggered a cascade of market failures and froze global credit, Goldman Sachs mitigated significant financial losses despite admitting they spent the period "scrambling" to manage emerging risks. Following the turmoil, the bank faced intense reputational backlash for its resilience and government bailouts, prompting leadership to establish a Business Standards Committee, enhance transparency regarding derivatives, and commit to a more robust public dialogue about their societal influence.

  5. Goldman Sachs14 min

    Goldman Sachs at 150: Part 7 – Going Public (1999)

    Hank Paulson

    Facing a severe 1994 financial crisis and the strategic necessity of funding global expansion, Goldman Sachs leadership concluded that a public capital structure was essential to sustain a stable balance sheet and unlimited liability risk controls. On May 4, 1999, the firm executed the second-largest initial public offering in financial history at the time, raising capital primarily to distribute equity among existing partners and employees rather than diluting ownership to external investors. This transition, led by senior partners such as Henry Paulson and John Corzine, allowed the institution to scale operations into new markets while maintaining its unique biennial partnership elections and collaborative corporate ethos.

  6. Goldman Sachs18 min

    Goldman Sachs at 150: Part 6 – Going Global (1989)

    In the 1980s, Goldman Sachs strategically pivoted from a U.S.-centric firm to a global powerhouse by establishing London as its European hub and securing the British Gas privatization to link local markets with international capital. Under the leadership of John Weinberg, who demonstrated unwavering client commitment during the 1987 Black Monday crash, and successors like Bob Rubin and Stephen Friedman, the firm modernized its operations by integrating quantitative risk management and recruiting top-tier mathematical talent. This transformation, supported by a flat, collaborative culture and a focus on hiring diverse talent, established a three-pillar framework of people, culture, and strategy that defined the firm's dominance in global finance over the following three decades.

  7. Goldman Sachs17 min

    Goldman Sachs at 150: Part 5 – Takeoff (1976)

    John Whitehead, John Weinberg

    Since 1985, the firm has navigated six or seven orderly CEO transitions, a succession pattern John Whitehead and John Weinberg established by codifying core principles to scale from a partnership of 800 employees to a global institution of 8,000. Their 1976 co-leadership era successfully separated strategic development from client relationship management while maintaining a "white knight" reputation for defending clients against hostile takeovers. This enduring culture prioritizes long-term trust and the client-first ethic as the primary assets ensuring the organization's 150-year longevity.

  8. Goldman Sachs17 min

    Goldman Sachs at 150: Part 4 – Changing Times (1969)

    Gus Levy, Sidney Weinberg, Bob Mnuchin, Bob Rubin, Steve Friedman

    In the early 1960s, Gus Levy redefined Goldman Sachs by transitioning it from a conservative investment bank into a trader-led market maker capable of handling massive institutional volume. His innovative block trading strategies and a culture of relentless accessibility navigated the firm through a 1970s liquidity crisis, establishing a legacy of institutional leadership that endured beyond his 1976 death. This structural shift not only secured the firm's position as a Wall Street hub but also instilled a permanent culture of vigilance and high standards that continues to shape Goldman Sachs' operations.

  9. Goldman Sachs18 min

    Goldman Sachs at 150: Part 3 – Recovery (1930)

    Sidney Weinberg

    Following the 1929 stock market crash, Sidney Weinberg rose from a janitor to lead Goldman Sachs through two decades of financial adversity, personally restoring client trust and building a network of high-profile corporate clients. Under his centralized control, Weinberg prioritized long-term relationships over immediate gains, orchestrating the landmark 1956 public offering for Ford Motor Company to cement the firm's status as a premier investment bank. His leadership legacy, characterized by "controlled ambition" and integrity, survived him after he stepped back from daily operations in 1963, leaving behind a client list and reputation that sustained the firm for decades.

  10. Goldman Sachs12 min

    Goldman Sachs at 150: Part 2 – Hubris (1929)

    Henry Goldman, Waddill Catchings, Walter Sachs

    During the 1920s, leadership under Waddell Catchings pivoted Goldman Sachs toward aggressive leverage and the creation of the highly risky Trading Corporation, a move that nearly destroyed the firm following the 1929 market crash. Although the catastrophic collapse of the Trading Corporation reduced its stock from $326 to $1.75 and triggered a $100 million lawsuit from 42,000 stockholders, the legal separation of the entity from the main partnership allowed the original family-controlled firm to survive the Great Depression. This near-failure ultimately cemented a culture of constitutional pessimism and risk aversion, ensuring that future decision-making would prioritize long-term institutional stability over short-term profit maximization.

  11. Goldman Sachs16 min

    Goldman Sachs at 150: Part 1 – Beginnings (1869)

    Emily Beynon

    Founded in 1869 by immigrant Marcus Goldman and later expanded by his son-in-law Samuel Sachs and son Henry Goldman, the firm evolved from a niche commercial paper dealer into a dominant investment bank through a unique leadership dynamic and aggressive market innovation. Pioneering critical financial practices such as the underwriting of non-utility retailers and the development of the Price-to-Earnings ratio, the partners successfully floated major companies like Sears and Macy's while navigating competition from established giants like J.P. Morgan. This strategic combination of calculated risk-taking and client-focused ingenuity transformed the organization from a basement operation into a globally influential institution that maintained its core values despite significant operational changes over the first century of its existence.

  12. a16z30 min

    Founding Stories: Anchorage

    Chris Dixon, Diogo Monica, Nathan McCauley, Katie Haun

    Founders Nathan and Diogo, previously instrumental in scaling security at Square and Docker, established Anchorage Digital to address the operational limitations of traditional cold storage for institutional crypto assets. The firm deploys a crash-resistant custody architecture that enables active on-chain participation, including staking and governance voting, while simultaneously serving as a founding node operator for the independent Libra Association in Geneva. This dual strategy aims to legitimize the broader cryptocurrency ecosystem by combining regulated fiduciary safeguards with a decentralized blockchain designed for global scalability and mass adoption.

  13. a16z22 min

    The Economics of Term Sheets

    Scott Kupor

    This presentation dissects economic term sheet mechanics using hypothetical venture firms Haiku and Indigo to illustrate how varying liquidation preferences and option pools directly impact founder ownership. By contrasting Haiku's participating 1x preference with Indigo's non-participating structure, the analysis demonstrates that while Indigo offers less immediate dilution, Haiku's smaller capital injection and option pool size yield a different risk-reward profile for the founding team. The session concludes by framing the choice between these competing $2 million versus $4 million offers as a strategic calculation of runway extension versus long-term upside, pending a future discussion on governance rights.

  14. The Economist6 min

    Secrets of the deep ocean

    Karl

    Scientists aboard the Australian Government's RV *Investigator* are surveying unexplored Tasmanian seamounts to assess deep-sea ecosystems at depths exceeding 1,000 meters. While Marine Protected Areas established in the 1990s show positive signs of recovery with returning urchin populations and anemones, the data reveals that the foundational stony coral matrix damaged by bottom trawling has not reformable over the past two decades. These findings will guide future conservation policies and promote sustainable fishing practices by highlighting the long-term resilience limits of these unique habitats.

  15. Milken Institute1h 22m

    Toward a Healthier Future

    Will Durant, Mike Milken, Tanisha Carino, Michael Milken, Francis Collins, Susan Desmond-Hellmann, Bernard J. Tyson, Seema Verma, Sue Desmond-Hellman

    Representatives from the Gates Foundation, Kaiser Permanente, CMS, and NIH converged to outline a unified strategy shifting global health systems from reactive treatment toward proactive prevention and precision medicine. Leaders highlighted specific breakthroughs in gene therapy, AI-driven neural decoding, and data interoperability while proposing structural reforms to align financial incentives with long-term population wellness and disease eradication. The consensus among these major institutions emphasizes that future economic prosperity and reduced healthcare costs depend on integrating community infrastructure, digital infrastructure, and innovative financing models to address challenges ranging from mental health crises to rare genetic disorders.