Latest Interviews
Showing 1–3 of 3 transcripts.
Clear all filters- Sequoia Capital7 min
Open Evidence Captures Doctors’ Collective Wisdom with AI ft. Zachary Ziegler
OpenEvidence, a medical search tool used daily by over 25% of US physicians, recently enabled an internal medicine doctor to successfully manage an in-flight emergency for an immunocompromised cancer patient without diverting the aircraft. By synthesizing current literature and CDC data, the platform confirmed the patient did not require immediate intervention and provided a targeted treatment protocol that ensured a positive outcome upon landing. Building on this high-volume, real-time performance, the company is now expanding into direct workflow integration and developing an Aggregate Clinical Wisdom initiative to encode expert consensus from top specialists across various fields.
- All-In Podcast17 min
Inside the All-In Summit: Behind the Scenes of the World's Greatest Conference 🚀
JD Vance, Elon Musk, Sergey Brin, Peter Thiel, Megyn Kelly, Mearsheimer, Sachs, Travis Kalanick, Marc Benioff, Woody Hoburg, Chamath, Jason, Friedberg, TheZachEffect, Zach
The Year Three conference featured a diverse lineup of high-profile guests, including Vice Presidential candidate J.D. Vance and Elon Musk, who discussed political independence, AI development, and economic expansion amidst tight security. Notable speakers such as John Mearsheimer, Travis Kalanick, and astronaut Woody Hobart contributed to dynamic segments on geopolitics, enterprise software, and scientific scales that defined the event's unscripted format. The gathering concluded with social festivities and a forward-looking toast, highlighting the organizers' intent to foster debate through an eclectic mix of political, technological, and scientific discourse.
- Y Combinator24 min
Kathryn Minshew at Startup School NY 2014
Kathryn Minshew, Catherine Minshew, Zach, Alex, Melissa, Adrienne, Doug
Catherine Minshew, a former McKinsey consultant, co-founded The Muse to bridge a gap in job discovery by prioritizing career content before listing positions, eventually growing the platform to serve one million monthly users despite initial design flaws and 148 investor rejections. Her strategy involved a ruthless product pivot advised by Y Combinator to focus on core value, aggressive zero-cost user acquisition tactics, and a founding philosophy that values shipping imperfect products over perfection while honoring verbal commitments. The company now partners with 200 major brands including Uber and Gucci, demonstrating how identifying specific user evangelists and maintaining strict value alignment can overcome early market skepticism.