Dr. Francis Collins

Smart on Science: How Today's Patients Are Driving Cures

Kim McCleary, Bray Patrick Lake, Joe Selby, Mace Rothenberg, Lou DiGennaro, Tony Coles, Dr. Francis Collins

Five healthcare leaders, including representatives from Pfizer, PCORI, and the NIH, convened to discuss the paradigm shift from paternalistic care models to active patient partnerships in drug development. The panel highlighted how the Precision Medicine Initiative, corporate adaptations like Pfizer's early patient integration, and PCORI's methodology have accelerated trial designs and improved outcomes by prioritizing patient-defined endpoints. Moving forward, the industry aims to leverage real-world data and shared governance to reduce the $2.2 billion cost of development while ensuring research addresses the specific needs and lived experiences of patients.