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Garen Staglin

Showing 1–2 of 2 transcripts.

  1. Milken Institute1h 5m

    Alzheimer's Disease: Rewriting the Playbook

    LaTese Briggs, Michela Gallagher, Todd Rainwater, Lauren Miller Rogen, Garen Staglin, Garen King Jr., Daniel Arbus, Elizabeth Scharf, Amir, Mark Reuthmeyer

    Leading scientists and philanthropists convened to address the projected surge in Alzheimer's prevalence and its looming $1.1 trillion economic impact by 2050, shifting research focus from the failed amyloid hypothesis to tau-targeted interventions and early prodromal treatment. The panel highlighted strategic initiatives such as the TAO Consortium's $100 million investment in tauopathies, the proposed $10 billion global social impact bond, and new collaborative models designed to accelerate FDA approval through consortium-based data sharing. By combining precision medicine, open science, and stigma-reduction advocacy, these stakeholders aim to de-risk early-stage development and attract pharmaceutical investment to prevent a global health crisis.

  2. Milken Institute58 min

    Cracking the Code of Addiction and Mental Health

    Lynn Goldman, Thomas Insel, Gary Mendell, Richard Pops, Garen Staglin, Nora Volkow

    A panel of experts from NIDA and public health organizations identifies the opioid crisis as a preventable epidemic driven by systemic healthcare failures, including aggressive pharmaceutical marketing and inadequate medical training, which have caused mortality rates among white non-Hispanic Americans to rise for the first time in history. To address this, the group advocates for mandating CDC prescribing limits, expanding access to proven medication-assisted treatments, and shifting workplace cultures to reduce stigma, emphasizing that the primary obstacle remains the implementation of existing evidence-based protocols rather than a lack of scientific knowledge. Despite these proposed solutions facing significant barriers such as insurance coverage gaps and reimbursement policies that delay care, the consensus holds that coordinated policy changes could reduce new addiction rates by half and reverse decades of escalating overdose deaths.