Josephine Chen
Showing 1–2 of 2 transcripts.
- Sequoia Capital50 min
Deal Velocity, Not Billable Hours: How Crosby Uses AI to Redefine Legal Contracting
Crosby, Ryan Daniels, John Sarihan, Josephine Chen
Crosby operates as an AI-first law firm that replaces traditional software models with an integrated service where lawyers and engineers collaborate side-by-side to automate contract review. By rejecting the billable hour in favor of per-document pricing and deploying specialized AI agents alongside human oversight, the firm accelerates negotiation lifecycles to enable single-turn resolutions. This structural innovation targets the underserved "long tail" of legal work, democratizing high-quality contract services while redefining junior attorney roles as managers of autonomous AI systems.
- Sequoia Capital58 min
Arc Institute's Patrick Hsu on Building an App Store for Biology with AI
Patrick Hsu, Josephine Chen, Pat Grady
The ARC Institute, led by Patrick Hsu, has launched EVO2, a generative foundation model trained on genomic sequences across all domains of life to predict the functional consequences of genetic variants with state-of-the-art accuracy. By reclassifying Variants of Unknown Significance, this open-source tool aims to transform genetic testing outcomes and prevent unnecessary medical interventions while establishing a roadmap toward simulating virtual cells by 2030. This initiative reflects a strategic shift within ARC to merge academic rigor with industrial application, utilizing evolutionary data to build a unifying theory of biology rather than focusing solely on traditional drug design.