Latest Interviews
Showing 181–195 of 541 transcripts.
Clear all filters- Milken Institute45 min
Credit Markets in Transition | Global Conference 2025
Michael Piwowar, Michael Buchanan, Peter Gleysteen, Deborah Orida, Michael Zawadzki, Mike Pivovar, Mike Buchanan
Panelists analyzed the current macroeconomic landscape characterized by tariff uncertainty and Federal Reserve rate cuts, while highlighting a $30 trillion private credit market reshaped by regulatory changes that drive capital from banks to non-competitive partners. Industry leaders identified investment opportunities in infrastructure, asset-backed finance, and investment-grade credit, noting that resilient fundamentals and low leverage support default rates under 50 basis points despite weakening investor sentiment. The discussion concluded with a strategic pivot toward multi-asset credit approaches and structural diversification to mitigate volatility risks and capitalize on market dislocations for tactical offense.
- All-In Podcast24 min
The Formula for Building America's Happiest City: Miami Mayor Francis Suarez | All-In Live
Francis Suarez, Chamath, Jason, Friedberg
Outgoing Miami Mayor Francis Suarez concludes his tenure by highlighting record-low homelessness, the city's lowest-ever homicide count, and historic economic growth driven by tax cuts and deregulation. His administration achieved these results by rejecting high-tax models in favor of aggressive regulatory reforms, including AI-driven permitting and public-asset leverage to fund major projects like the Bright Line rail. As Suarez prepares to leave office in September, he emphasizes his strategy of eliminating outdated barriers to attract global business while navigating complex challenges like national housing shortages and substance abuse crises.
- Milken Institute42 min
The American Athlete: Feeding the US Olympic Pipeline | Global Conference 2025
Pete Stavros, Maya Andrews, Dan Gable, Karch Kiraly, Carl Lewis
Former Olympic legends Maya Andrews, Dan Gable, Karch Kiraly, and Carl Lewis convened to address the critical financial instability threatening U.S. collegiate Olympic sports and the resulting vulnerability of the national team ahead of the 2028 Los Angeles Games. The panelists diagnosed a crisis where rising costs and revenue concentration have decimated programs in wrestling and volleyball, then proposed strategic remedies ranging from philanthropic reinvestment and antitrust lobbying to tuition reform and enhanced financial transparency. Beyond structural solutions, the discussion highlighted philosophical imperatives regarding the mastery of failure and disciplined routines, arguing that preserving the current NCAA-subsidized pipeline is essential for sustaining American athletic dominance and societal leadership.
- Goldman Sachs30 min
Alnylam’s Yvonne Greenstreet on RNAi and a ‘golden era’ in biotech
Alnylam Pharmaceuticals leverages a decade of RNA interference research to achieve a 55% clinical success rate and recently secured approval for Amvutra to treat hereditary transthyretin-mediated amyloidosis. Under CEO Yvonne Greenstreet, the company aims to become a top-five biotech leader by 2026 through a five-year strategy to deliver 25 clinical programs and expand into common diseases like hypertension. To reach this goal, Alnylam integrates AI-driven drug design with a culture of diversity and patient advocacy to de-risk development and target tissues beyond the liver, including the central nervous system.
- All-In Podcast29 min
Antonio Gracias: DOGE updates, Voter fraud, Finding 'Big Balls' | All-In Live from Miami
Antonio Gracias, Chamath, Jason, Friedberg, David Sacks
Antonio Gracias leads a Doge team implementing a zero-defect operational overhaul of the US government bureaucracy, targeting a 15% reduction in waste and fraud by eliminating NGO spending and restoring full office productivity. The administration combines aggressive voter fraud detection using restored SAVE database protocols with a meritocratic recruitment strategy that prioritizes problem-solving over credentials to secure high-caliber engineering talent. This approach supports a dual-track immigration policy that balances open borders for skilled professionals with strict border sovereignty measures and temporary public service models.
- Milken Institute30 min
Earvin "Magic" Johnson on Legacy, Leadership, and LA's Future | Global Conference 2025
Earvin "Magic" Johnson, Alex Rodriguez, Jason Kelly, Earvin Johnson
At the Milken Conference, Magic Johnson and Alex Rodriguez discussed their transformative mentorship and a portfolio of high-impact business ventures ranging from the Washington Commanders to a pioneering Starbucks franchise. Johnson detailed his strategy of securing institutional capital by over-performing on early real estate deals and outlined his leadership philosophy centered on strategic planning, authentic player relationships, and an unwavering winning culture for the LA Dodgers and other owned teams. The dialogue concluded with an emphasis on leveraging athletic experience to mentor the next generation while measuring success by philanthropic impact rather than revenue alone.
- All-In Podcast33 min
Sergey Brin, Google Co-Founder | All-In Live from Miami
Sergey Brin, Chamath, Jason, Friedberg
Sergey Brin returned to active software development at Google, leveraging his technical influence to challenge internal restrictions while championing autonomous AI capabilities demonstrated by the Gemini 2.5 model. He outlined Google's strategic pivot toward simulated robotics, hybrid hardware abstraction, and a tiered monetization strategy that balances open-weight releases with premium access for advanced compute-heavy models. Furthermore, Brin highlighted a cultural shift where AI tools are reshaping talent management and predicted a future dominated by voice-first interfaces and adaptive learning environments.
- Goldman Sachs42 min
Harvard’s Raj Chetty on upward mobility in America
Research by Dr. Raj Chetty and the Opportunity Atlas team reveals a sharp decline in intergenerational income mobility, with the likelihood of children out-earning their parents dropping from 92% for the 1940 cohort to roughly 50% for those born in the mid-1980s. The analysis identifies four primary drivers of upward movement, with cross-class social capital acting as the strongest predictor, while highlighting successful local interventions like Charlotte's $160 million investment and Vaughan College's model that combines high access with strong technical outcomes. These findings suggest that targeted strategies integrating financial aid with social support can effectively reverse trends of regional inequality without relying solely on broad federal policy changes.
- Milken Institute21 min
A Conversation with Former First Lady of the United States Jill Biden | Global Conference 2025
At the 28th annual Milken Institute Global Conference, Dr. Jill Biden and Esther Kroffa outlined the Women's Health Network's strategy to address historical data gaps and the $1 trillion global economic opportunity by shifting funding reliance to the private sector. The initiative targets critical breakthroughs in areas like endometriosis diagnostics and Alzheimer's care while deploying a digital platform and pooled investment fund to dismantle data silos and accelerate inclusive innovation. By reframing women's health as a universal business imperative rather than a niche category, the network aims to impact millions of lives globally by 2025 through enhanced research inclusion and strategic capital allocation.
- Milken Institute38 min
A Conversation with US Secretary of the Treasury Scott Bessent | Global Conference 2025
Scott Bessent, Richard Ditizio, Michael Milken
The 28th annual Milken Institute Global Conference convened 1,000 speakers under the theme "Toward a Flourishing Future" to address critical resource gaps in health, connectivity, and global wealth distribution while urging for inclusive coalitions to bridge societal divides. Concurrently, Treasury Secretary Scott Bessent outlined the Trump administration's economic agenda, which prioritizes trade tariffs to boost domestic manufacturing, a "big beautiful bill" of tax cuts and deregulation, and an aggressive strategy to lower the federal deficit by 1% annually. The administration further signaled a shift toward "safe, sound, and smart" financial regulation, strategic partnerships with Ukraine, and a focus on maintaining U.S. dominance in AI and quantum computing to foster a "new golden age" of prosperity.
- Sequoia Capital32 min
OpenAI’s Sam Altman on Building the ‘Core AI Subscription’ for Your Life
Sam Altman, Jens Nordvigsen, DAN GALPIN, SAM SACCONE
OpenAI has evolved from a 14-person research lab into a commercial powerhouse driven by the GPT-3 API and the viral ChatGPT platform, which now serves 500 million weekly active users. Under Sam Altman's leadership, the organization prioritizes high-impact small teams and a vision of becoming a personalized AI operating system while navigating a market where startups outpace legacy enterprises in agility. The company's roadmap emphasizes the transition from text-based assistants to autonomous agents by 2025, with future infrastructure expected to facilitate seamless agent-to-agent communication and eventual robotics applications.
- Sequoia Capital31 min
Google's Jeff Dean on the Coming Transformations in AI
This presentation outlines the trajectory of deep learning from its 2012 scaling breakthroughs toward a future of multi-modal agents and physical robotics capable of performing thousands of tasks within two years. It details a converging industry landscape where a handful of foundational models drive a secondary ecosystem of efficient, specialized architectures supported by Google's upcoming Ironwood TPU generation and Pathways system. The discussion further projects how these advancements will revolutionize scientific discovery, democratize virtual engineering through junior-level AI assistants, and reshape economic structures via dynamic compute allocation.
- Sequoia Capital24 min
Anthropic CPO Mike Krieger: Building AI Products From the Bottom Up
Mike Krieger, Trevor Johnsen, Sam Nelsons, Emily Fortuna, Dave Elliott Smith, Mike McDonald Jr.
At a recent strategic discussion, Anthropic executive Mike McDonald Jr. outlined a paradigm shift where the distinction between AI-generated and human-created content becomes irrelevant, emphasizing instead that provenance via blockchain and compelling human storytelling will define future value. The organization is operationalizing this vision through a "bottoms-up" product philosophy and the development of the Model Context Protocol (MCP), which evolved from engineer-led integrations to establish a standardized, open framework for autonomous agent interactions and economic transactions. Internally, this approach has resulted in massive AI adoption with over 70% of code reviews generated by machines, though leaders note that non-technical organizational bottlenecks now pose the primary constraint on high-velocity development.
- Milken Institute43 min
A Conversation with Citadel CEO Ken Griffin | Global Conference 2025
Ken Griffin critiques current U.S. fiscal policies and immigration frameworks, warning that regressive tariffs and restrictive visa rules threaten to erode national flexibility while failing to retain the international scientific talent essential for future growth. He advocates for aggressive K-12 and higher education reforms driven by school choice and data transparency to dismantle systemic inefficiencies, citing Success Academy and his own Harvard philanthropy as models for overcoming institutional inertia. Looking forward, Griffin aims to mobilize an estimated $150 billion in generational wealth to fund private-sector innovations and inspire a new era of scientific ambition similar to the 1960s space race.
- Sequoia Capital34 min
How AI is Reinventing Software Business Models ft. Bret Taylor of Sierra
Bret Taylor, Ravi, Robin Wright, Clay, DAN GALPIN, BRETT HESTERBERG
Brett Taylor, formerly CTO of Facebook and current leader of Sierra, outlines a transformative vision for the AI sector where specialized, outcome-based agents replace traditional websites and software subscriptions. Taylor advises entrepreneurs to evolve beyond personal technical expertise to avoid stagnation, emphasizing that the next trillion-dollar opportunities lie in vertical-specific solutions that deliver tangible business results rather than generic productivity tools. Through Sierra's innovative pricing model that charges only for autonomous resolutions, the company exemplifies a strategic shift toward selling outcomes, positioning startups to outmaneuver legacy incumbents struggling to adapt their business models to this new era.