Latest Interviews
Showing 871–885 of 1,549 transcripts.
Clear all filters- All-In Podcast32 min
#AIS: Divvy Homes CEO Adena Hefets breaks down the state of the US housing market
Adena Hefets, Chamath, Calacanis, Friedberg, Adina
Divi Homes addresses the stark wealth inequality driven by asset appreciation and restrictive lending standards by offering a non-traditional homeownership model that allows customers with limited down payments to build equity. Operating across sixteen major markets with a customer base comprising 50% people of color and 80% female-led households, the company has achieved a 51% purchase success rate among participants who complete its three-year term. Funded by a recent $200 million Series investment from Tiger Global, Divi projects a path to profitability with an all-in margin near 25% while navigating a supply-constrained housing market.
- Y Combinator22 min
How To Deal With Setbacks
Dalton Caldwell, Michael Seibel
This analysis reframes startup setbacks as an unavoidable structural element rather than a sign of failure, challenging the "movie analogy" that suggests a single victory resolves all challenges. It outlines common adversity categories including investor rejections, co-founder friction, and legal threats while introducing tactical frameworks like the "Worst Case" inventory to help founders distinguish between catastrophic failure and recoverable operational hiccups. By mastering their reaction to these inevitable punches, founders can establish a resilient cultural blueprint that transforms adversity into a stabilizing force for the entire organization.
- Goldman Sachs41 min
Ryan Watts, CEO and Co-Founder of Denali Therapeutics
Founded by CEO Dr. Ryan Watts in 2015, Denali Therapeutics is leveraging proprietary blood-brain barrier technologies and genetic insights to accelerate clinical-stage programs for Alzheimer's, Parkinson's, and ALS. The company is currently initiating pivotal late-stage trials for Parkinson's and Hunter syndrome while prioritizing preventative strategies and shorter-term milestones in lysosomal storage diseases to validate its pipeline. By combining this technical approach with a culture that accepts failure as part of discovery, Denali aims to shift neurodegenerative treatment from late-stage intervention to early disease prevention within the next decade.
- Y Combinator36 min
Save Your Startup During an Economic Downturn
Dalton Caldwell, Michael Seibel
This framework defines the critical distinction between "default alive" startups, which can reach profitability before exhausting cash, and "default dead" companies facing imminent extinction without new funding. It identifies the fatal pinch as a common trap where founders increase burn rates due to investor pressure or misaligned incentives, often exacerbated by media biases that mask high fundraising failure rates. To escape this cycle, the analysis advocates for immediate operational discipline, such as drastic headcount and ad spend reductions, citing Justin.tv's rapid transition from burning $250,000 monthly to generating $1.2 million in profit as a proven recovery model.
- Goldman Sachs29 min
Joe Bae, Co-CEO of KKR and Founder of The Asian American Foundation
KKR Co-CEO Joe Bae outlines the firm's expansive Asian strategy, which now accounts for a quarter of the company's business through diversified infrastructure and private credit investments targeting a millennial demographic. Amidst macroeconomic headwinds like inflation and geopolitical shifts, Bae emphasizes supply chain resiliency and a balanced energy transition while leveraging KKR's localized workforce to navigate global risks. Beyond finance, he details the establishment of the Asian American Foundation to dismantle the model minority myth and drive systemic community support through corporate advocacy and educational initiatives.
- Goldman Sachs27 min
Jean Case, CEO of The Case Impact Network and Chairman of the National Geographic Society
Jean Case outlines the critical distinction between impact investing and ESG frameworks while addressing SEC transparency concerns and the urgent need for "greenwashing" prevention as trillions of dollars transfer to Millennial and Gen Z investors. She highlights a shifting market where diverse leadership teams drive superior returns and where fossil fuel strategies are evolving from divestment to active engagement, particularly amidst geopolitical pressures like the Ukraine crisis. Case illustrates these concepts through App Harvest's vertical farming success and personal reflections on navigating career risks, ultimately advocating for a strategic pivot to "fail forward" when community alignment is compromised.
- Goldman Sachs20 min
Changes at the Top: Spinoffs, Separations and Restructurings
Ben Snider, David Dubner, Allison Nathan
Amidst slowing U.S. growth and persistent inflation, the S&P 500 is shifting valuation focus toward high-profit-margin companies, driving a surge in corporate restructuring activities. Global spinoff volume has doubled the five-year average to over $100 billion as management teams prioritize portfolio rationalization and capital allocation efficiency. While transaction structures range from initial-step IPOs to spin-mergers, Goldman Sachs forecasts this trend will persist through 2022 as firms seek to optimize operations against sustained economic headwinds.
- All-In Podcast38 min
E76.5: Food shortage, China's grand plan, inflation, French election plus an All-In Summit preview
Chamath, Calacanis, Friedberg, David Sacks, Jason
The inaugural All-In Summit in Miami will feature confirmed speakers such as Palmer Luckey and Keith Rabois alongside sought-after guests like John Mearsheimer and Peter Thiel, who will engage in structured dialogues on topics ranging from global food security and China's geopolitical leverage to macroeconomic inflation and payment network disruption. The three-day event utilizes a new format of solo presentations followed by Socratic discussions to address critical issues including the potential for regime instability in Europe and the dismantling of financial duopolies. Held May 15–17, the sold-out conference combines this substantive programming with themed social events while encouraging diverse viewpoints to foster open debate on emerging geopolitical and technological trends.
- Goldman Sachs32 min
Gina Ortiz Jones, Under Secretary of the Air Force
Under Secretary Gina Ortiz-Jones outlined the Department of the Air Force's strategic shift toward integrated deterrence and sixth-generation space dominance to counter the pacing threat of China while sustaining critical security assistance to Ukraine. Simultaneously, the leadership is enforcing rigorous data-driven policy reforms to dismantle systemic biases identified in promotion pipelines and address barriers facing women of color and Asian men. These operational and personnel changes are driven by Ortiz-Jones's personal commitment to inclusive growth, aiming to modernize the force and ensure sustained talent retention through both combat readiness and equitable access.
- Goldman Sachs29 min
Kate Ryder, Founder & CEO of Maven Clinic
Co-founded and led by CEO Kate Rider, Maven is the first female-led telehealth startup to achieve unicorn status, addressing critical gaps in women's healthcare through a network spanning fertility, postpartum care, and menopause. The company recently expanded its strategic footprint by partnering with Microsoft and five Fortune 15 employers while simultaneously extending coverage to Medicaid populations to combat high maternal mortality rates. By shifting incentives from volume-based procedures to value-based outcomes, Maven has reported a 30% reduction in NICU admissions and is actively working to reform the systemic inequities that affect one in eight couples facing infertility.
- Goldman Sachs35 min
Paula Kerger, President & CEO of PBS
PBS CEO Paula Kerger oversees the decentralized network's 16-year evolution from a command-and-control model to a trust-based system that balances federal infrastructure support with local fundraising. The organization differentiates its portfolio by prioritizing high-investment educational documentaries and investigative journalism like *Frontline* while transitioning to digital platforms to ensure equitable access in underserved communities. Looking ahead, Kerger aims to expand funding for national arts and science programming while reinforcing the network's role as a non-partisan counterweight to media consolidation and algorithmic polarization.
- Y Combinator20 min
How Future Billionaires Get Sh*t Done
Dalton Caldwell, Michael Seibel
The presentation analyzes Paul Graham's distinction between "maker" and "manager" schedules to demonstrate how maximizing uninterrupted deep work is critical for technical founders. It advocates for specific productivity tactics, such as prioritizing written to-do lists, enforcing meeting accountability, and eliminating social media distractions to protect focus. Furthermore, the discussion redefines startup failure as a high-value achievement and argues that total commitment to core activities like customer validation and product building outweighs the safety of hedging bets against risk.
- Goldman Sachs28 min
Russell Wilson, Denver Broncos Quarterback; Super Bowl XLVIII Champion
Russell Wilson, Nicole Pullen-Ross
Nine-time Pro Bowl quarterback Russell Wilson leverages a decade of NFL records and his unique background in baseball and basketball to challenge conventional athletic and business limits. Wilson applies his "neutral thinking" philosophy and strategic risk management to build a diverse portfolio including West to East and the Good Man Brand while directing the Why Not You Foundation to distribute over 70 million meals. Looking forward, he aims to redefine the potential of professional athletes by prioritizing immediate excellence and community leadership over traditional career trajectories.
- Goldman Sachs40 min
Eric Adams, Mayor of New York City
New York City Mayor Eric Adams is redefining the city's governance by forging a corporate covenant to accelerate economic recovery and establishing strict performance metrics for agencies like the FDNY and Department of Buildings to reduce bureaucratic delays. To create a foundation for prosperity, his administration is simultaneously addressing public safety through a dual strategy of enforcement and root-cause intervention while launching major infrastructure initiatives such as a new onshore wind port and a Brooklyn-based Cyber Command Center. Anchored in his former law enforcement experience, Mayor Adams aims to transform the city into a globally business-friendly hub that balances fiscal innovation with social cohesion and public health resilience.
- Goldman Sachs29 min
Tricia Glynn, Managing Director at Advent International
Managing Director Tricia Glenn outlines Advent's investment philosophy, which prioritizes revenue growth and seeks three-to-fivefold returns by partnering with consumer retail disruptors rather than focusing on cost-cutting. She details how the firm navigates a shifting 2022 macro landscape driven by supply chain disruptions and rising interest rates by targeting "pearls" with exceptional talent and capitalizing on the live-selling revolution. Glenn further emphasizes the necessity of systemic diversity and risk-taking to secure actual power for underrepresented leaders, citing portfolio successes like Olaplex and Lululemon as evidence that aggressive capital deployment drives industry inflection.