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  1. Goldman Sachs10 min

    Talks at GS – Dr. Vivek Murthy: The Global Epidemic of Addiction

    Dr. Vivek Murthy

    Former Surgeon General Dr. Murthy reflects on his tenure while highlighting the opioid epidemic as a defining global crisis exacerbated by historical medical misinformation and aggressive pharmaceutical expansion. He advocates for a shift in public health strategy from merely treating mental illness to proactively fostering emotional well-being through social connection and contemplative practices. Ultimately, Murthy emphasizes that building a culture of trust and openness requires top-down leadership to protect both employee health and organizational performance.

  2. Y Combinator24 min

    VMware Cofounder Diane Greene with Jessica Livingston at the Female Founders Conference

    Diane Greene, Jessica Livingston

    VMware co-founder Diane Greene navigated early skepticism and capital constraints to build the virtualization giant while retaining full voting control, later exiting to found Bebop before its 2017 sale to Google. Following her tenure on the boards of Intuit and Google, Greene leveraged her governance experience and strategic relationships to pivot enterprise software automation toward machine learning. She now advocates for cloud market consolidation driven by superior security models and advises founders to prioritize specific board expertise over prestige when constructing their leadership teams.

  3. Goldman Sachs21 min

    Lessons from Lloyd: Advice to Our Summer Interns

    Lloyd Blankfein

    Goldman Sachs CEO David Solomon reflects on his 35-year tenure, tracing his path from a Harvard law graduate who rejected initial offers to a strategic leader who leverages the firm's risk management expertise for its new consumer lending division. He champions diverse corporate policies, including support for marriage equality, while addressing global economic resilience and the market anxieties surrounding an extended economic cycle. Solomon concludes by warning of geopolitical tensions like the Thucydides Trap and emphasizing the importance of a well-rounded background alongside technical acumen for long-term professional success.

  4. Y Combinator27 min

    Emily Weiss on the Insights That Grew Glossier - With Amy Buechler at the Female Founders Conference

    Emily Weiss, Amy Buechler

    Glossier, led by CEO Emily Weiss, leverages its sister publication *Into the Gloss* and a 600% annual growth trajectory to scale its Direct-to-Consumer beauty model while maintaining accidental profitability with $40 million in raised capital. The company prioritizes product quality and community transparency over traditional retail tactics, driving expansion through peer-to-peer recommendations and a strategic shift to physical locations that function as cultural hubs rather than sales counters. As Weiss directs focus toward a new European headquarters, the firm exemplifies a market shift where data-driven community engagement replaces conventional advertising to cultivate brand loyalty among a predominantly female workforce.

  5. Y Combinator44 min

    Making Music and Art Through Machine Learning - Doug Eck of Magenta

    Doug Eck, Craig Cannon

    Google's Magenta project deploys open-source machine learning tools like NSynth and SketchRNN to assist human creators in generating novel music and art rather than replacing them. By leveraging deep learning architectures such as LSTMs and reinforcement learning, the team enables the interpolation of distinct sounds and the generation of complex long-form structures while emphasizing active user participation through creative coding. As the initiative expands its community via its open-source platform, it aims to refine evaluation methods and integrate with professional workflows to support a future where human artists adapt by focusing on unpredictable, emotionally raw expressions.

  6. Goldman Sachs10 min

    Talks at GS – Danielle Weisberg and Carly Zakin: Changing the Face – and Format – of News

    Danielle Weisberg, Carly Zakin

    Co-founders Danielle Weisberg and Carly Zakin launched The Skimm in 2012 to bridge the news consumption gap for female millennials by delivering concise, nonpartisan global updates via email. The company now generates revenue through strategic brand partnerships and a forward-looking "Skim Ahead" subscription service, with the editors personally curating all content to maintain a trusted, conversational voice. As the business has grown, the founders have expanded their mission to address misinformation while advising new entrepreneurs to prioritize value articulation over academic credentials in a challenging startup landscape.

  7. Y Combinator2h 14m

    IPFS, CoinList, and the Filecoin ICO with Juan Benet and Dalton Caldwell

    Juan Benet, Dalton Caldwell, Craig Cannon, Dan Galpin, Francesc Campoy, Mark Mandelmann, Mark Blythouse, Mark Mandelbaum, Chris Broadfootnich

    Protocol Labs, founded by Juan Bonet, is developing the InterPlanetary File System and its incentivized Layer-2, Filecoin, to transition internet infrastructure from centralized, location-based models to a decentralized, content-addressed network that ensures data sovereignty and censorship resistance. By replacing traditional venture capital with token-based funding models like CoinList, the organization enables long-term open-source research while utilizing Proof of Replication to create a liquid global market for unused storage capacity. This initiative aims to solve systemic inefficiencies in credit assignment and data redundancy, positioning Filecoin as a competitor to major cloud providers while fostering a new economy where protocol contributors are compensated directly through native network value.

  8. Y Combinator5h 9m

    Female Founders Conference 2017

    Avni Patel-Thompson, Emily Weiss, Laura Behrens Wu, Padmashree Warrior, Aileen Lee, Elizabeth Lyons, Vanessa Torridilla, Erica, Morgan de Bon, Diane Greene, Kirsty Nathoo, Carolyn Lebe, Anu Hariharan, Adora Chung, Jessica Livingston, Kat

    The Female Founders Conference brought together prominent industry leaders like Avital Lee, Kate Winslet, and Aileen Lee to analyze the nine distinct factors that differentiate successful startups from unicorns. Prominent founders from companies such as Poppy, Glossier, and NIO shared case studies on overcoming funding rejections, pivoting from failure, and building inclusive cultures within male-dominated sectors. The event concluded with YC partners debunking common myths about early-stage investment while emphasizing that persistent storytelling and rigorous data preparation are essential for women founders navigating systemic bias.

  9. Y Combinator53 min

    Ex Machina's Scientific Advisor - Murray Shanahan

    Murray Shanahan, Craig Cannon

    Academician Roger Penrose details the historical persistence of the frame problem in artificial intelligence, tracing his own career shift from symbolic logic to computational neuroscience and back to a proposed synthesis of symbolic concepts within modern deep learning. Drawing parallels with the evolution of chess and Go under AlphaGo, Penrose critiques current AI's data inefficiency and lack of semantic understanding while offering insights from his consultation on the film *Ex Machina* regarding the relationship between physical embodiment and consciousness. He concludes that while hardware capable of matching the human brain is imminent, achieving true Artificial General Intelligence still requires fundamental conceptual breakthroughs that transcend specialized algorithms or Asimov-style ethical constraints.

  10. Milken Institute1h 21m

    Lunch Program: A Conversation with Wilbur L. Ross, Jr., Jim Yong Kim and Jamie Dimon

    Wilbur L. Ross, Jr., Jim Yong Kim, Jamie Dimon, Michael Klowden, Willow Bay, David Rubenstein

    The 20th Milken Institute Global Conference convened approximately 4,000 attendees from 60 nations to address the theme of "Building Meaningful Lives" through strategic pillars of capital access, job creation, and health. Key figures including U.S. Commerce Secretary Wilbur Ross, World Bank President Jim Yong Kim, and JPMorgan Chase CEO Jamie Dimon presented diverging perspectives on trade policy, global development, and domestic infrastructure reform. Their discussions emphasized shifting from GDP-centric metrics to human capital investment, while outlining specific strategies to overcome regulatory hurdles and automate job transitions to drive future economic growth.

  11. Milken Institute1h 2m

    Chess and the Art of War: Strategies That Win, from Grandmaster Magnus Carlsen

    Magnus Carlsen, Erik Schatzker, Danny Rensch, DAN GALPIN, Rockwell Shaw, Frank Motek, Yascha Monk, Igor Tuchinsky, Steven Knapp, Toby Post, James Kuffner, Brett Bryan, Noaf Altari, Danny Kane, David Wall, Ari Milken, Bailey Milken, Eric Olives, Mike Tyson

    World champion Magnus Carlsen demonstrated his elite cognitive endurance by winning most games in a rapid "sudden death" simul against ten opponents, including WorldQuant CEO Igor Tuchinsky and representatives from major tech and academic institutions. While adhering to a philosophy that prioritizes winning over artistic expression and relies on flexible physical optimization, Carlsen managed the extreme time pressure of ten-minute games by rapidly controlling the center and converting technical endgames. The event highlighted the intense mental strain of simultaneous high-level play, featuring a notable draw against David Wall that resulted from a clerical error where Carlsen mistakenly believed the game had concluded.

  12. Milken Institute59 min

    Leading a Healthy Life

    Paula Zahn, Rip Esselstyn, Michael O. Johnson, Erik Oberholtzer, Dean Ornish, Shazi Visram

    Dr. Dean Ornish leads a panel demonstrating that integrated lifestyle interventions involving plant-based nutrition, stress management, and social connection can reverse chronic conditions ranging from heart disease to prostate cancer while simultaneously reducing long-term healthcare costs. The discussion identifies structural barriers such as food deserts and industrial subsidies as primary obstacles, proposing community-based solutions like affordable plant foods and distributed health platforms to ensure equitable access. Ultimately, the group concludes that individual behavioral choices, driven by the joy of living rather than fear, serve as the definitive determinant of health and can override genetic predispositions to prevent premature mortality.

  13. Milken Institute1h 1m

    A Conversation with Sherry Lansing

    Sherry Lansing, Stephen Galloway

    Former 20th Century Fox and Paramount Pictures chairman Sherry Lansing spent 25 years leading Hollywood's most prominent studios, producing blockbusters like *Titanic* and *Forrest Gump* while overcoming gender bias and high-pressure production crises. In 2003, she transitioned from film to philanthropy, founding the Sherry Lansing Foundation to advance cancer research and education after a pivotal meeting with Jimmy Carter. Now 72, Lansing reports greater authenticity and joy in her charitable work than in her decades of studio management, with plans to remain active until age 100.

  14. Goldman Sachs12 min

    Talks at GS – Eddie Huang: Food, Culture, Identity

    Eddie Huang

    Executive Producer and author Nahnatchka Khan reflects on her memoir *Fresh Off the Boat* and the television adaptation as pivotal moments in transitioning from defensive survival mechanisms to intentional identity formation. She critiques the show for diluting authentic Asian experiences into universal white narratives while rejecting the "model minority" stereotype through her personal journey of culinary preservation and leadership at her restaurant, Bauhaus. Ultimately, she advocates for a cultural shift that prioritizes shared humanity over differences, utilizing a management philosophy that blends high performance with deep personal care to foster genuine employee loyalty.

  15. Y Combinator34 min

    How Should Business Schools Prepare Students for Startups? – Jeff Bussgang and Michael Seibel

    Jeff Bussgang, Michael Seibel, Craig Cannon

    YC CEO Michael Seibel and HBS lecturer Jeff Busgang debate the persistent gaps between MBA education and startup execution, identifying technical deficits, lack of commitment, and excessive research as primary reasons for high rejection rates. While Business Schools like Harvard are adapting through physical integration with engineering departments and new joint degrees, the traditional curriculum often fails to instill the immediate traction and hands-on coding skills required by venture capitalists. Ultimately, Seibel advises non-technical founders outside top hubs to prioritize working at early-stage startups over pursuing an MBA, citing real-world experience as superior preparation for building transformational ventures.