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  1. Milken Institute1h 24m

    LIVE: Part 1: A Conversation With Christine Lagarde | Part 2: The Investors' View

    Christine Lagarde, Michael Klowden, Gerard Baker, Stephanie Flanders, Tom Finke, David Hunt, Scott Minerd, Ronald O'Hanley, Lara Warner

    IMF Managing Director Christine Lagarde and a panel of investors convened to address global economic fragility characterized by synchronized growth slowdowns, persistent low inflation, and rising sovereign and corporate debt risks. Discussions highlighted divergent regional trajectories with the US showing resilience while Europe faces structural vulnerabilities, alongside critical concerns regarding China's Belt and Road sustainability and the potential for a US-China trade agreement. The event concluded with urgent calls for structural reforms in infrastructure, labor participation, and digital investment to combat inequality, warning that future crisis response capacity is limited by high debt levels and political polarization.

  2. Y Combinator6 min

    How to Get and Test Startup Ideas - Michael Seibel

    Michael Seibel

    This session challenges the notion that startup ideas must be perfect at inception, using Justin Kan's co-founding of Twitch to illustrate how prioritizing deep personal connection to a problem over the concept itself drives resilience. Kan advises founders to maintain "problem books" rather than idea logs, validate issues through direct community impact, and rigorously handpick early users to test minimum viable products. Ultimately, the discussion emphasizes that successful entrepreneurs must fall in love with the customer's pain point rather than their initial product, ensuring the team remains uniquely qualified to solve a specific, verified need.

  3. Goldman Sachs14 min

    Sarah Casanova: Chief Executive Officer, McDonald’s Holdings (Japan)

    Sarah Casanova

    McDonald's Japan CEO Sarah Casanova, a 28-year veteran of the company, spearheaded a strategic turnaround that modernized 92% of its 2,900 locations to restore customer trust and drive revenue in the world's second-largest McDonald's market. Her leadership model explicitly connects diversity initiatives to business performance, leveraging the fact that women control half of consumer spending decisions while challenging female employees to overcome confidence barriers to secure promotions. Casanova further advocates for an inclusive management style that prioritizes continuous improvement and mentorship, asserting that effective leadership in her global industry requires adaptability rather than adherence to traditional masculine personas.

  4. Goldman Sachs22 min

    Jean Case: Author, "Be Fearless"

    Jean Case, John

    Gene Case, Chairman of the National Geographic Society and CEO of the Case Foundation, recounts her career trajectory from a scholarship student to a pivotal figure in the early internet sector who secured a critical $3 million settlement to launch America Online. Critiquing the current lack of venture capital diversity and startup consolidation in the United States, she advocates for a risk-tolerant philanthropic approach that funds "people and ideas that can change the world." Drawing on her book *Be Fearless*, Case emphasizes five principles for navigating change, urging leaders to prioritize bold, disruptive action over the protection of endowments to address pressing social challenges.

  5. Milken Institute1h 1m

    New Opportunities From a World in Transition

    Michael Piwowar, Daniel Farley, James McCormack, Angela Rodell, Bart Turtelboom, Dan Farley

    A comprehensive analysis of current global transitions highlights the interplay between persistent political populism, aging demographics in advanced economies, and China's strategic shift toward high-value manufacturing. These macroeconomic realities are driving a recalibration of investment expectations toward a 5% annual return while identifying opportunities in emerging markets' technological leapfrogging, Arctic logistics, and ESG-integrated risk management. Furthermore, the event emphasizes that effective adaptation to these structural shifts requires robust immigration policies, educational system modernization, and a focus on diversity as a tangible driver of financial performance.

  6. Milken Institute59 min

    Global Capital Markets

    Rachel Pether, Hazem Ben-Gacem, Jeremy Coller, Tom Finke, Joseph Naggar, Michael Clowden

    Panelists Joe Nagai, Tom Fink, and Jeremy Collar analyze the convergence of geopolitical headwinds and market cycles, noting a shift from valuation-driven public markets to private asset classes focused on operational value creation and distress opportunities. The discussion highlights a strategic pivot toward real estate resilience, private credit maturation, and emerging market exposure in China and the Middle East, while addressing specific risks like currency volatility and divergent regional economic performances. Concluding with industry forecasts, the experts anticipate a new paradigm where the global economy transitions toward consumption and service dominance, driving capital flows into private markets as traditional credit metrics face obsolescence.

  7. Jane Street1h 9m

    A Language-Oriented System Design

    Nathan Linger

    The Ontology system presents a dual-language architecture that manages organizational permissions through an English-facing interface backed by a dependently typed, deductive database engine. It distinguishes between hard-coded primitives, extensional tables, and intentional logical rules to enforce strict type safety, ensuring that data retrieval returns verifiable proof objects and automatically maintains referential integrity through cascading deletion and trash mechanisms. While the internal Prolog-like inference engine mitigates undecidability risks via execution budgets, the design allows for extensible permission modeling by uploading new type declarations without requiring code-level system upgrades.

  8. Milken Institute58 min

    Asset Management Outlook 2018

    Joseph Dowling, Rick Lacaille, Daniel Lopez-Cruz, Neal Wilson, Hoda Abou-Jamra, Mark Wycroft

    State Street's Rick Lakai, Invesco's Daniel Lopez Cruz, and EJF's Neil Wilson analyzed critical structural shifts in portfolio construction, US banking consolidation, and private equity supply dynamics at a recent industry panel. The discussion highlighted State Street's push to separate smart beta from active management, Wilson's identification of regulatory arbitrage opportunities in regional banking, and Lopez Cruz's warnings regarding the difficulty of sustaining alpha as private equity fundraising concentrates among top funds. Furthermore, the experts evaluated emerging market allocations amid US-China tensions, the divergent paths of ESG regulation between the US and Europe, and systemic liquidity risks associated with covenant-light leveraged loans and thematic ETFs.

  9. Milken Institute58 min

    From Stigma to Treatment: Tackling the Global Mental Health Crisis

    LaTese Briggs, Lynne Goldberg, Annalisa Jenkins, Elie Karam, Colin Lawlor

    A global panel of experts, including Dr. Lattice Briggs, Annalisa Jenkins, and Colin Lawler, highlights a rising mental health crisis driven by chronic stress, sleep deprivation, and systemic barriers that threaten to cost the global economy $16 trillion by 2030. The discussion identifies ignorance, stigma, and an overreliance on institutional "sick care" as primary obstacles, while advocating for a shift toward community-based prevention, digital interventions, and emerging pharmaceuticals like psilocybin. Speakers emphasize that resolving this crisis requires treating mental health as a human rights issue and integrating preventative care into existing community infrastructure to sustain the future global workforce.

  10. Milken Institute58 min

    Investing in Volatile Markets

    Manus Cranny, Todd Boehly, Joshua Harris, Mike Novogratz, Amanda Staveley, Cornelia Meyer, Mary Daly, Tim Gosher, Yusuf Kutsy

    Mike Novogratz, Joshua Harris, Amanda Stavely, and Todd Boehly convened to analyze a market landscape defined by impending political volatility from the Mueller report, a slightly inverted yield curve, and aggressive private equity leverage levels. The panelists distinguished between transitory trade tensions and a persistent tech war, while highlighting divergent investment strategies ranging from high-yield litigation funding and UK infrastructure to specific allocations in Bitcoin as a hedge against sovereign debt crises. Ultimately, the discussion concluded that despite dislocated assets and recessionary pricing, central banks retain sufficient firepower to stabilize the economy through future downturns.

  11. Milken Institute20 min

    Across Sectors and Borders | Part 2: Entrepreneurship, Technology, and Social Investing

    Rich Ditizio, Edgar Bronfman Jr., Richard D'Atizio

    Bronfman outlines a transformative economic landscape where technology disrupts traditional music distribution, while the Endeavor Global network leverages mentorship to sustainably scale entrepreneurship across 33 countries. Simultaneously, he argues that addressing climate change requires moving beyond emission reduction to mass-scale Direct Air Capture, utilizing modular technology to economically sequester billions of tons of CO2 annually. Together, these strategies exemplify an impact investing philosophy that rejects the compromise between social good and profit, insisting that scalable solutions must generate financial returns to drive global transformation.

  12. Milken Institute1h 1m

    World-class Healthcare: Investing in Biomedical Innovation

    Tanisha Carino, Christopher Hite, Bryan Johnson, Sean Parker, D.A. Wallach

    Moderated by Dr. Tanisha Carino in Abu Dhabi, this session analyzed the convergence of global biomedical innovation and market dynamics, highlighted by the historic $92 billion Bristol-Myers Squibb acquisition of Celgene as a catalyst for pipeline stability. The discussion detailed how falling hard science costs and platforms like Ginkgo Bioworks are compressing development timelines, while investment strategies increasingly favor foundational tools over singular disease treatments to address the translational gap between academic research and commercial viability. Despite concerns regarding venture capital concentration in oncology and systemic US healthcare incentives, the event projected that long-term pricing decreases and extended lifespans could emerge from global regulatory evolution and the integration of AI-driven data collection.

  13. Goldman Sachs19 min

    Warby Parker Co-Founders and Co-CEOs Neil Blumenthal and Dave Gilboa

    Neil Blumenthal, Dave Gilboa, Rob Sweeney

    Founded in 2008 by Wharton classmates Neil Blumenthal and Dave Gilboa, Warby Parker disrupted the eyewear market by combining an omnichannel retail strategy with a proprietary social mission that has distributed millions of glasses globally. The company distinguishes itself through physical locations designed to drive organic engagement and technological innovations like virtual try-ons and remote prescription checks, which collectively maintain a Net Promoter Score of 86. By prioritizing human-centric store experiences and rigorous cultural documentation, the founders have scaled the business to over 88 stores while rejecting the notion that physical retail is obsolete in favor of a seamless digital-physical integration.

  14. a16z17 min

    Security Markets: The Lay of the Land

    Joel de la Garza

    This presentation critiques the current cybersecurity landscape as a flawed ecosystem where misaligned incentives and security-by-attachment fail to address root causes like human error and misconfiguration. Despite billions in venture capital, experts highlight that 93% of breaches stem from preventable mistakes rather than sophisticated malware, driving a market shift toward zero trust architectures and native security models exemplified by Apple and Google. Looking forward, the industry anticipates a transition to an all-cloud environment where traditional data centers shrink and blockchain facilitates threat intelligence sharing through standardized compliance and cyber insurance mechanisms.

  15. Milken Institute51 min

    Sir Richard Branson and Michael Milken in Conversation with Kevin O'Leary

    Sir Richard Branson, Michael Milken, Kevin O'Leary, Richard Branson

    Speakers Richard and Michael analyze a sharp decline in Western faith in free enterprise driven by student debt, stagnant real estate returns, and wealth inequality, while contrasting this with optimism in emerging markets like Vietnam and China. They argue that successful entrepreneurship now relies on balancing visionary leadership with operational management to navigate deregulation, tax competitiveness, and global capital flows, noting that SMEs have become the primary engines of job creation. Furthermore, the discussion outlines solutions for systemic challenges, including a universal carbon tax to address climate change and for-profit space exploration to ensure both environmental sustainability and human survival.