Latest Interviews
Showing 181–195 of 2,499 transcripts.
Clear all filtersHow He Turned a Blood Test Startup Into $7B OS for Healthcare
Commure has secured $70 million in a new funding round led by General Catalyst, bringing its total valuation to $7 billion and cumulative capital to approximately $750 million. The company now supports 200 million annual patient encounters and is deploying this capital to transition its point solutions into a unified AI-powered operating system while accelerating R&D. With a commitment to a public market IPO, Commure aims to eliminate administrative work tax in the healthcare sector, targeting $1 trillion in systemic efficiency gains through its expanding global workforce and enterprise partnerships.
- Milken Institute30 min
Backing What's Next: A Conversation with Serena Williams | Global Conference 2026
Serena Williams transitioned from angel investing to launching Starfire Ventures, a firm established to support underrepresented founders in sectors like financial services and technology. Under the leadership of General Partner Serena Williams and co-general partner Beth Farah, the firm differentiates itself by applying an "AI first" investment thesis while providing deep operational support to scale companies such as Isuzu. This strategic approach addresses the historical lack of capital allocation to women by combining institutional discipline with a mission to empower entrepreneurs serving "middle America."
- a16z11 min
How Founders Can Build for Law Enforcement and First Responders | The a16z Show
David Ulevitch, Col. Jeffrey Glover, Rahul Sidhu, Colonel Glover
Law enforcement agencies are rapidly transitioning from traditional physical confrontation to AI-driven investigative frameworks that utilize autonomous drones, sensor fusion, and behavioral analytics to prevent crime and optimize resource allocation. This shift is evident in successful interventions where technology de-escalated potential threats and in the adoption of data-driven well-being programs that have reversed historical union resistance to body-worn cameras. Looking ahead, international intelligence sharing and advanced fraud detection are becoming central to a new policing model that prioritizes technical analysis over brute force, requiring developers to deeply understand operational contexts to effectively deploy these inevitable advancements.
- All-In Podcast1h 17m
Trump-Xi Summit, Benioff: "Not My First SaaSpocalypse," OpenAI vs Apple, Multi-Sensory AI, El Niño
Trump, Xi, Benioff, Scooter the Dog, Chamath, Jason, Friedberg, TheZachEffect
The first face-to-face summit in six years between President Trump and President Xi established a framework for U.S.-China stability through commitments to keep the Strait of Hormuz open while averting Taiwan's nuclear conflict, all while securing a massive trade expansion involving 200 Boeing jets and increased energy imports. This geopolitical realignment was reinforced by a high-profile delegation of American CEOs, including Elon Musk and Jensen Huang, who navigated complex regulatory environments to advance U.S. interests in AI, payment systems, and software services across China. Concurrently, the event highlighted global market shifts driven by artificial intelligence and severe climate risks, as leaders addressed the economic resilience of enterprise platforms and the looming threat of a record-breaking El Niño year that could trigger worldwide food insecurity.
- Milken Institute59 min
Private Equity: Value Creation Under New Rate Regimes | Global Conference 2026
Hugh MacArthur, Joe Baratta, Martín Escobari, Raoul Hughes, Meredith Jenkins, Pete Stavros
Leading private equity firms like KKR and Blackstone are pivoting from speculative AI experimentation to targeted operational efficiency, achieving modest EBITDA improvements while redefining software investment criteria to prioritize durable infrastructure over vulnerable point solutions. As the industry confronts extended holding periods and a capital stack constrained by high entry multiples, firms are shifting focus from financial engineering to deep operational value creation, leveraging specialized sourcing and geographic diversification in markets like Japan and Germany. Looking ahead, the sector anticipates a surge in liquidity driven by a wave of maturing assets and a strategic expansion of retail capital access, provided that new vehicles maintain structural parity with institutional standards to avoid conflict-of-interest pitfalls.
- Goldman Sachs21 min
Has the AI rally gone too far?
Tony Pasquariello, Josh Schiffrin, Dominic Wilson, Tom
Market analysts Josh Shiffrin and Dominick Wilson assess a resilient global economy driven by record-high AI capital expenditure and robust US and Korean earnings, while identifying unresolved geopolitical tensions in Iran as the primary downside risk. Although speculative excesses have emerged in semiconductor sectors and credit markets remain tight, the consensus predicts the Federal Reserve will maintain a "watch and wait" stance with rate cuts unlikely until 2026 unless labor markets soften significantly. Consequently, investors are advised to hedge against energy supply shocks and position for a long-term dollarization trend as Asian markets outperform a lagging Europe.
- Milken Institute1h 1m
Emma Grede "Start with Yourself: A New Vision for Work & Life": Author Talk | Global Conference 2026
Emma Grede, Stephanie Phair, Kristin Juszczyk, Ashley Graham, Jens Grede
Kim Kardashian West shares her core philosophy of radical ownership and direct communication, advocating for visible proximity to decision-makers over the pursuit of work-life balance. Leveraging her experience as a founder of billion-dollar ventures like Skims and Good American, she challenges women to reject performative diversity and embrace strategic partnerships to build sustainable, inclusive businesses. Looking ahead, she aims to facilitate a massive transfer of wealth to the next generation of female leaders by using her platform to fund and mentor women from underprivileged backgrounds.
- Milken Institute59 min
Global Economic Outlook: Navigating Growth, Risk, and Opportunity | Global Conference 2026
Conrad Kiechel, Zanny Minton Beddoes, Kristalina Georgieva, Mohamed Kande, Ariel Szarfsztejn, Mike Wirth
A two-month closure of the Strait of Hormuz has removed 14 million barrels daily from the global market, driving Brent crude near $115 while depleting strategic reserves and forcing the IMF to adopt adverse economic scenarios. Simultaneously, the AI sector has pivoted from generative tools to agentic automation, eliminating entry-level roles and triggering an international cyberarms race. These converging crises create a volatile environment where Europe faces energy and innovation lag, whereas nations securing reliable power and flexible capital markets are positioned to dominate the coming decades.
- Goldman Sachs21 min
McLaren Racing's Lando Norris and Zak Brown: Building a High-Performance Team
Lando Norris, Zak Brown, Anthony Gutman
McLaren driver Lando Norris secured the 2025 Formula One World Drivers' Championship following a dramatic mid-season comeback, yet he recently missed a race start due to unprecedented power unit battery failures. As the team navigates 2026 regulatory changes that have widened the performance gap and altered vehicle dynamics, Norris and team principal Zak Brown are leveraging a collaborative "Papaya Rules" culture to translate driver feedback into rapid technical adaptations. This strategy aims to restore competitiveness against the "big four" constructors while ensuring the 900-person ecosystem maintains resilience against the complex, sophisticated nature of modern racing.
- a16z24 min
The Founders Who Left Tesla to Rebuild America | a16z
Erin Price-Wright, Turner Caldwell, Drew Baglino
Led by former Tesla executives Turner Caldwell and Drew Baglino, Mariana Minerals and Heron Power are building a vertically integrated domestic supply chain for critical minerals and solid-state power infrastructure to close a fifty-year capability gap with China. The companies deploy proprietary autonomous operating systems to accelerate refinery ramp-ups and modernize the grid, aiming to secure over 500 jobs while establishing a new industrial model that prioritizes physical assets over software algorithms. By co-locating manufacturing with energy generation and leveraging silicon carbide semiconductors, the initiative seeks to re-industrialize the U.S. economy through a "minerals mandate" that mobilizes private capital to rebuild the foundational infrastructure of AI dominance.
- All-In Podcast1h 35m
How We Grew Koch Inc. to $150 Billion Without Going Public: Charles & Chase Koch
Chase Koch, David Friedberg, Charles Koch
Charles Koch and his son Chase detail the evolution of Koch Industries from a 1940s crude oil operation into a global "republic of science" employing 130,000 people, guided by principles that prioritize capability-driven expansion, creative destruction, and contribution-motivated leadership. They illustrate how these core tenets facilitated massive transformations such as the Georgia-Pacific acquisition while driving the "Stand Together" movement to reform education and criminal justice systems against rising authoritarianism. The discussion concludes by outlining their strategy to leverage AI through permissionless innovation and Koch Labs to democratize human potential, emphasizing that long-term profitability and societal progress depend on adhering to first principles rather than short-term political constraints.
- Milken Institute34 min
Conversation with BlackRock CEO Larry Fink & Brookfield Corp CEO Bruce Flatt | Global Conference '26
Larry Fink, Bruce Flatt, Laurence D. Fink, Michael Milken
Bruce Flint of Brookfield and Larry Fink of BlackRock refuted private credit liquidity concerns while projecting a $10 trillion global infrastructure expansion driven by urgent shortages in power, compute, and defense-grade facilities. The executives detailed how hyperscalers are shifting from self-funding to external financing models, facilitating a massive capital transition where private credit and long-term asset managers fund AI data centers and autonomous security infrastructure. Furthermore, these leaders highlighted a structural evolution in retirement investing and asset consolidation, noting that consistent 12% annual returns and bespoke 50-year lock-up periods are essential to support this new "K-economy" where massive capital blocks outcompete traditional public equities.
- Stanford Online1h 0m
Stanford CS153 Frontier Systems | Scott Nolan from General Matter on Energy Bottlenecks
General Matter, founded in 2024 with a $900 million Department of Energy contract, is establishing a uranium enrichment facility in Paducah, Kentucky, to address the critical energy bottleneck constraining AI scaling. By reviving domestic enrichment capabilities that were dismantled after the Cold War, the company aims to secure a sustainable supply of nuclear fuel for Small Modular Reactors before the decade's end. This initiative directly targets the gap between stagnant global grid expansion and the aggressive power demands of industrial AI, creating high-skilled jobs while reducing reliance on foreign enrichment sources.
- a16z1h 14m
Goldman Sachs Chairman on Why Finance Adopts AI Differently | a16z
A senior financial leader outlines a risk management philosophy centered on rigorous contingency planning rather than prediction, while highlighting the unique systemic threats posed by autonomous AI and untested technology. The speaker details how Goldman Sachs maintained stability during the 2008 crisis through strict collateral agreements and mark-to-market accounting, preserving a partnership culture that prioritizes firm-wide ownership even after its IPO. Drawing parallels between financial crises and active shooter scenarios, the discussion advises current and future technology leaders to build public trust proactively and cultivate broad resilience to navigate an uncertain future.
- Milken Institute26 min
A Conversation with Venezuelan Democratic Leader Maria Corina Machado | Global Conference 2026
Maria Corina Machado, Fareed Zakaria
Nobel Peace Prize recipient María Corina Machado, having escaped Venezuela's repressive regime, advocates for a three-phase democratic transition that prioritizes electoral legitimacy, judicial restoration, and the privatization of the oil sector to address a $190 billion debt and 650% inflation. Her roadmap, supported by U.S. Secretary of State Marco Rubio, outlines a strategic framework involving debt restructuring with the IMF and the recruitment of the diaspora to rebuild infrastructure, while ensuring accountability for crimes against humanity through the International Criminal Court. Despite significant security challenges and international opposition from state actors like Russia and Cuba, Machado posits that the military's potential support and the nation's critical mineral reserves could facilitate a "nearshoring" economic boom and position Venezuela as a leader in artificial intelligence.