Latest Interviews
Showing 2431–2445 of 9,648 transcripts.
Clear all filters- a16z30 min
Ben Horowitz on Leadership and Culture
Ben Horowitz discusses the critical role of decisive action in leadership while outlining Andreessen Horowitz's strategic pivot to invest in defense technology and advocate for crypto-based AI infrastructure. The firm leverages its Washington, D.C. presence to shape policy, arguing that the Biden administration's refusal to engage on these issues necessitated an alignment with the current administration to foster regulatory clarity. Simultaneously, a16z deploys advanced surveillance and drone technologies in Las Vegas to improve public safety, demonstrating a practical application of these innovations to reduce profiling errors and increase crime clearance rates.
- The Economist23 min
Division multiplication: the UAE’s foreign meddling
Jason Palmer, Greg Karlstrom, Moeka Iida, John Fassman
The United Arab Emirates faces international condemnation and legal challenges at the International Court of Justice for allegedly supplying weapons to Sudan's Rapid Support Forces while simultaneously advancing diplomatic ties with the EU and acting as a mediator in the Russia-Ukraine war. In Japan, thousands of farmers staged rare protests during a historic rice shortage driven by climate damage and supply chain distortions, forcing the government to release strategic reserves despite structural policies that continue to suppress domestic production. Concurrently in the United States, the cultural debate over gender-neutral language has intensified politically, prompting a linguistic reassessment of English pronouns that highlights the historical validity and practical necessity of the singular "they" amidst efforts to codify usage through government mandates.
Superpower Raises $30M Series A Led by Forerunner
Superpower, led by founder Jacob Peters, secured a $30 million Series A round led by Forerunner Ventures to advance its vision of replacing fragmented healthcare with an AI-driven concierge model. The company leverages a three-part architecture of data centralization, diagnostic intelligence, and action-oriented marketplace tools to provide comprehensive health monitoring at a fraction of traditional costs. By capitalizing on widespread metabolic dysfunction and Peters' personal health crisis, Superpower aims to disintermediate the current system and build a vertically integrated preventative care network.
- The Economist21 min
Cardinals in: choosing the next pope
Jason Palmer, John Hooper, Sarah Burke
Following Pope Francis's death, the Catholic Church prepares for a high-stakes conclave where key figures like Camerlengo Kevin Farrell and Dean Giovanni Battista Re must navigate deep ideological divisions regarding geopolitical strategy and sexual abuse accountability. Simultaneously, Mexico faces a deepening humanitarian crisis as the discovery of a CJNG cartel training camp with cremation ovens underscores the rising disappearance rate under current and previous administrations, prompting President Claudia Sheinbaum to propose reforms despite severe forensic resource gaps. In the entertainment sector, the *Minecraft* film's record-breaking $300 million opening signals a potential revival for theatrical eventing by targeting the teenage demographic, even as unruly TikTok-fueled behavior forces theaters to implement strict attendance policies.
- Sequoia Capital46 min
Pricing in the AI Era: From Inputs to Outcomes, with Paid CEO Manny Medina
Manny Medina, Pat Grady, Lauren Reeder
Manny Medina outlines a strategic pivot for AI success toward narrow, high-utility applications that replace specific Business Process Outsourcing roles rather than general-purpose creative tasks. He details four emerging pricing frameworks, particularly agent-based billing that allows companies to allocate AI costs to human resources budgets, while warning that rising inference costs are compressing margins unless vendors shift to outcome-based revenue models. Medina concludes that sustainable growth requires founders to abandon broad market ambitions in favor of deep vertical expertise, utilizing paid to track unit economics as the industry transitions from trial-based excitement to contract renewals.
- a16z39 min
The Dual-Use Founder: Vets Now Building For America
Matt Shortal, John Doyle, David Tuttle, Grant Jordan
Three former military officers and defense technology veterans founded Cape and related ventures to address the asymmetry between legacy, high-cost defense systems and modern low-cost threats like commercial drones. By rejecting traditional bureaucratic structures, these companies prioritize rapid iteration and dual-use technologies that serve both national security and critical infrastructure needs. Their collective strategy aims to bridge the funding gap between early-stage prototypes and large-scale deployment while advocating for faster government acquisition cycles to match commercial innovation speeds.
- Goldman Sachs42 min
Warburg Pincus CEO Jeffrey Perlman on navigating a trickier private equity environment
Warburg Pincus CEO Jeffrey Perlman, who succeeded Chip Kaye in September 2025, outlined the firm's strategy to navigate a structural interest rate environment and declining performance persistence by leveraging a $45 billion distribution record and a "diversification by design" approach. The discussion highlighted the firm's 30th anniversary expansion in Asia, where shifting from minority stakes to majority control aims to capitalize on two-thirds of projected global growth despite tariff disruptions. Looking forward, Perlman emphasized the transformative potential of Artificial Intelligence in deal sourcing and operational efficiency while reinforcing a culture that prioritizes the institution over individual legacy.
- Milken Institute58 min
New Horizons for Accelerating Drug Repurposing
Dr. David Fajgenbaum, Ray, Kristen, Marianne Clancy, Christine Colvis
Hosted by TRiN and Faster Cures, this webinar featured experts from EveryCure, CURE HHT, and NCATS to examine strategies for accelerating the repurposing of existing drugs for rare diseases. Presenters detailed how AI-driven knowledge graphs and patient-led advocacy successfully navigated financial, intellectual property, and regulatory hurdles to secure approvals for conditions like Castleman's disease and Hereditary Hemorrhagic Telangiectasia. The session concluded with a consensus that generating clinical evidence and securing payment pathways are more critical than intellectual property protection for bringing generic therapies to new indications.
Dave CEO, Jason Wilk: The Best Performing Fund Would Only Back YC Founders on Their Second Time
Dave, Jason Wilk, Harry Stebbings
Dave CEO Jason Goldman details how the fintech firm reversed a 98% market capitalization decline to reach $1.13 billion by leveraging AI-driven underwriting to slash credit loss rates and achieve significant profitability without layoffs. The company utilizes cashflow-based analysis across 12 million accounts to offer low-cost credit alternatives to legacy overdraft fees, projecting continued expansion into buy now, pay later and longer-duration lending. Goldman argues that the firm's capital efficiency and removal of traditional debt structures position it to disrupt the $3 trillion credit card market, though he cautions against regulatory overreach that could stifle consumer access to fair lending.
- The Economist20 min
A man of the people: Pope Francis has died
Pope Francis, Jason Palmer, Anne Rowe, Avantika Chalkoti, Juergen Esser, Andrew Palmer
Pope Francis has implemented a radical reform strategy within the Catholic Church by prioritizing mercy and direct engagement while facing internal resistance from the Curia regarding child abuse protocols and doctrinal changes. Simultaneously, the global high-protein market is surging due to GLP-1 drug usage and shifting consumer demographics, prompting major manufacturers like Danone and Nestlé to launch specialized products despite warnings of unnecessary supplementation. In the corporate sector, organizations are increasingly addressing workplace turnover by replacing indirect "quiet firing" tactics with purpose-alignment workshops, a method proven to improve productivity while naturally separating low-performing employees.
- The Diary Of A CEO2h 25m
Former FBI Agent: If They Do This Please RUN! Narcissists Favourite Trick To Control You!
Former FBI counterintelligence specialist Joe Navarro leverages thirty years of law enforcement experience to teach that non-verbal communication is an evolutionary hardwiring used to assess threat and establish dominance in negotiations. He details specific physiological indicators such as facial glabella movements and neck touching, while outlining strategies like controlling time and physical height to influence outcomes in high-stakes environments ranging from corporate leadership to espionage. Navarro concludes that mastering these behavioral cues allows individuals to bypass deception, create psychological comfort, and cultivate the self-mastery required for exceptional performance in an increasingly digital world.
- All-In Podcast1h 39m
Trump vs Harvard, Nvidia export controls, how DEI killed Hollywood with Tim Dillon
Trump, Tim Dillon, Chamath, Jason, Friedberg, David Sacks
The White House recently imposed indefinite export restrictions on NVIDIA's H20 chips, projecting a $5.5 billion earnings hit while prompting debates over whether enforcement will accelerate China's domestic semiconductor ambitions or effectively curb dual-use technology flows. Simultaneously, the Trump administration is contesting Harvard University over federal funding mandates, freezing billions in grants after the university refused to dismantle DEI programs and face a potential revocation of its tax-exempt status based on civil rights precedents. Experts warn that these geopolitical and educational crackdowns must address China's rising research parity with the U.S. while acknowledging that traditional university models may be too inefficient to sustain American scientific competitiveness without structural reform or AI-driven alternatives.
- Y Combinator38 min
How Zepto Became India’s Fastest Growing Startup
Zepto co-founders Aadit Palicha and Aadit Palicha (KB) scaled a Mumbai-based grocery startup into a $5 billion unicorn by pioneering a "customer backward" dark store model that delivers 1.5 million daily orders across 50 Indian cities in ten minutes. The company achieved financial efficiency by breaking even just over two years ago despite a global capital freeze, while diversifying revenue streams through advertising and new verticals like Zepto Cafe. Driven by a long-term vision to rival global giants like Amazon, Zepto leverages generative AI and a cost-effective Indian talent pool to expand beyond groceries into electronics and general merchandise.
Inside the $350M Pelosi Stock Tracker
Autopilot, formerly known as the Nancy Pelosi stock tracker, is a venture-backed fintech platform that has grown to manage $500 million in assets for 2.5 million users before pivoting to a creator economy model allowing influencers to offer tradable portfolios. The company leverages its history of tracking high-performing politicians like Nancy Pelosi and Richard Burr to highlight market timing disparities while advocating for the bipartisan "Pelosi Act" to ban congressional stock trading. Having generated eight-figure revenue without a down month, Autopilot is transitioning from a single-figure focus to a sustainable social investing ecosystem funded by roughly $7 million in venture capital.
- The Economist24 min
Gene genies: CRISPR’s critical moment
Jason Palmer, Rosie Bloor, Emily Steinmark, Leo Marani, Eleanor Whitehead
The 2020 Nobel Prize in Chemistry recognized Emmanuelle Charpentier and Jennifer Doudna for CRISPR, a precision gene-editing tool now enabling curative treatments like Kisjevi for sickle cell disease while facing regulatory hurdles distinct from traditional genetic modification. Simultaneously, Asian markets drove nearly two-thirds of global gold demand to hedge against currency instability and capital controls, with India and China leading consumption despite the trade deficits this high import volume creates. In New Zealand, an accelerated net brain drain of nearly 129,000 emigrants was fueled by economic recession and housing costs, as professionals migrated to Australia seeking higher wages under the Trans-Tasman Agreement.