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  1. All-In Podcast1h 19m

    E40: A Bestie gets COVID, Delta breakthrough, Billionaire Space Race & more

    Chamath, Calacanis, Friedberg, Richard Branson, Andy Weir, Jeremy England, David Sacks

    Venture capitalist David Sacks details his mild breakthrough Delta infection while discussing declining vaccine efficacy against the highly transmissible variant and the subsequent pressure for population-wide booster shots. Concurrently, the conversation expands to the private space sector's rapid maturation, highlighted by Virgin Galactic's successful commercial flight and surging venture capital investment, which sparks debate over prioritizing space exploration versus resolving terrestrial crises. The hosts further contextualize these developments through discussions on the psychological impact of breakthrough cases, potential policy shifts regarding vaccination mandates, and the emerging economic models of space tourism and satellite infrastructure.

  2. All-In Podcast1h 28m

    E36: New FTC Chair, breaking up big tech, government silent spying, Jon Stewart, wildfires & more

    Jon Stewart, Chamath, Calacanis, Friedberg, Lina Khan, Stephen Colbert, Obama, David Sacks

    FTC Commissioner Lina Khan was confirmed by a 69-28 Senate vote, initiating a policy shift from consumer welfare standards to market power analysis that targets major platforms like Amazon and Google with structural breakups. While experts Sacks and Thiel agree that monopolies threaten innovation and competition, they debate whether this new regulatory approach risks hyper-politicization or effectively liberates human capital for startups. The discussion further spans urgent civil liberties concerns regarding secret DOJ subpoenas against tech firms, allegations of pandemic-era censorship double standards, and the critical need for controlled burns to manage California's record-breaking wildfire crisis.

  3. All-In Podcast1h 23m

    E32: Behind the scenes of Elon hosting SNL, CDC failures, America's real-time UBI experiment & more

    Elon, Chamath, Calacanis, Friedberg, Jason, Stanley Druckenmiller, David Sacks

    David Sacks detailed Elon Musk's culturally impactful *SNL* appearance and a viral monologue joke, while also criticizing CDC guidance on outdoor transmission and alleging political collusion with teachers' unions. Macroeconomic analysts Stanley Druckenmiller and Sacks condemned federal overstimulation and California's misallocated surpluses as drivers of inflation and labor shortages. The conversation further explored a potential "Netscape moment" for synthetic biology, highlighting breakthroughs in stem cell therapy and nitrogen-fixing microbes alongside critiques of traditional media's declining influence.

  4. All-In Podcast1h 22m

    E31: Post-vaccination virtue signaling, pandemic lessons, immigration, Caitlyn Jenner for CA & more

    Caitlyn Jenner, David Sacks, David Friedberg

    David Sacks and Chamath Palihapitiya critique pandemic-era policies for relying on excessive conservatism that hindered economic recovery and eroded public trust, while highlighting the critical link between obesity and mortality. The discussion further outlines a shifting political landscape driven by a bipartisan consensus on antitrust enforcement, predicting the breakup of major technology monopolies by 2030 to address threats to democracy. Concluding with observations on local governance, the hosts contrast the safety and reopening trends in Austin against San Francisco, citing the Caitlyn Jenner gubernatorial campaign as a focal point for redefining public safety priorities.

  5. All-In Podcast1h 19m

    E29: Coinbase goes public, direct listings vs. IPOs, unions & more with Bestie Guestie Brad Gerstner

    Brad Gerstner, Chamath, Calacanis, David Sacks, Friedberg, Bezos, Drew Holden, Josh Hawley

    Brad Gershner, David Sacks, and panelists analyze direct listing advantages over traditional IPOs, citing Grab's $1 billion in savings and predicting 10-20% growth equity retracements due to normalization of Treasury yields. The discussion critiques union inefficiencies through Amazon's failed Alabama vote, while Sacks outlines a potential California gubernatorial campaign targeting teachers' unions and economic migration caused by regulatory hostility. Furthermore, the group argues that institutional trust has collapsed regarding pandemic responses and media coverage, advocating for decentralized financial alternatives and a private "Invest America" initiative to replace government stimulus.

  6. All-In Podcast1h 24m

    E23: Radical DAs, breaking down FB/Google vs. Australia, sustained fear post-vaccine & fan questions

    Calacanis, Friedberg, Ray Dalio, Chesa Boudin, J. Cal, Chamath Palihapitiya, David Sacks

    In this episode, Chamath Palihapitiya, David Sacks, and their co-hosts critique media integrity following Chesa Boudin's cancellation and Vlad Tenev's evasive interview while analyzing how the District Attorney's policies contributed to San Francisco's rising crime rates. The panel further discusses the economic implications of Australian news legislation, identifies critical bottlenecks in California's vaccine rollout, and evaluates macro risks such as global trade fragmentation and the potential loss of the dollar's reserve status. Concluding with their respective investment theses and missed opportunities, the hosts advocate for educational reforms in coding, biology, and entrepreneurship to prepare future generations for a shifting technological and geopolitical landscape.

  7. All-In Podcast1h 26m

    E19: Robinhood's GameStop decision: Why did it happen and how can it be prevented in the future?

    David Sacks, Jason, Friedberg, Chamath Palihapitiya

    Hosts analyzed the January 2021 GameStop short squeeze, detailing how Reddit users, Michael Burry, and Ryan Cohen pressured institutional shorts while Robinhood's trading restrictions sparked accusations of market manipulation. The discussion highlighted systemic flaws in clearing mechanisms and payment-for-order-flow models, contrasting the collective power of retail investors with risks of mob behavior and centralized censorship. Additionally, the conversation addressed Chamath Palihapitiya's California recall campaign for Governor Gavin Newsom, framing both financial and political movements as challenges to entrenched elite control.

  8. All-In Podcast1h 38m

    E17: Big Tech bans Trump, ramifications for the First Amendment & the open Internet

    Trump, David Sacks, Jason, Chamath, Anthony Noto, Friedberg

    In an emergency broadcast following the January 6th Capitol attack, hosts Chamath Palihapitiya, David Sacks, and Friedberg convened to reconcile internal conflicts while analyzing the event's political fallout and the subsequent deplatforming of Donald Trump. The group debated whether the riots constituted a coup or a riot, critiqued the lack of transparency in Big Tech censorship, and warned that private corporate actions against free speech could trigger global fragmentation or a new constitutional crisis. Ultimately, the hosts called for a shift from partisan outrage toward systemic solutions, advocating for regulatory utility models to protect democratic discourse while pledging to continue the podcast despite the chaotic national climate.

  9. All-In Podcast3h 0m

    E11: Election Night Special featuring Phil Hellmuth, Bill Gurley, Brad Gerstner & more!

    Phil Hellmuth, Bill Gurley, Brad Gerstner, Chamath, Michael Newman, Jon Cohen, Pete Buttigieg, Joe Biden, Jason Calacanis, David Friedberg, David Sacks

    Financial markets rallied and betting odds flipped violently as Donald Trump secured critical victories in Florida, Ohio, and Pennsylvania, driven by voter backlash against COVID-19 lockdowns and unexpected demographic shifts. While major media networks initially misjudged the election dynamics, the results projected a "soft landing" scenario where a potential Biden presidency coincides with a Republican Senate to ensure government gridlock and fiscal stability. Key swing states like Michigan, Wisconsin, and Arizona remain statistically tight, creating uncertainty over whether a clear winner will be declared or if a contested election will extend into early December.

  10. All-In Podcast11 min

    SPAC talk with Chamath Palihapitiya, David Friedberg, David Sacks & Jason Calacanis | from Episode 7

    Chamath Palihapitiya, David Friedberg, David Sacks, Jason Calacanis

    Chamath Palihapitiya positions Special Purpose Acquisition Companies as "IPO 2.0," offering founders certainty on valuation and proceeds while bypassing the underpricing risks of traditional investment bank roadshows. This strategy addresses a shrinking supply of public listings by enabling high-growth SaaS firms to target public markets earlier, specifically around a $50 million revenue run rate. Although the SPAC ecosystem now includes prominent figures like Bill Ackman and Reid Hoffman, Palihapitiya warns that success requires deep operational insight rather than mere financial arbitrage.

  11. All-In Podcast1h 24m

    E8: TikTok + Oracle, how privacy loss will impact society, economy & COVID outlooks for 2021

    Emily Yoffe, David Friedberg, David Sacks, Chamath Palihapitiya

    Panelists Chamath Palihapitiya, David Sachs, and David Friedberg addressed the security risks of TikTok's Chinese ownership and the economic implications of a prolonged zero-interest rate environment. The discussion also covered diverging forecasts on pandemic recovery, the potential for climate change solutions to drive future economic dominance, and the societal impacts of cancel culture on political discourse. Additionally, the conversation highlighted the strategic expansion of Special Purpose Acquisition Companies (SPACs) as a mechanism to reverse the decline in public listings and empower smaller enterprises to access capital.

  12. All-In Podcast1h 16m

    E7: California's collapse, how SPACs are opening the markets for growth stocks & more

    Chamath, Friedberg, Jason, David Sacks

    Jason Freeberg, David Sacks, and Chamath Palihapitiya analyze California's governance crises, attributing systemic failures in housing and law enforcement to union influence, regulatory capture, and a misaligned political economy that drives talent away from public service. The group further critiques the gig economy regulations under AB 5 while outlining a capital markets strategy favoring early-stage public listings via SPACs to maximize valuation growth over private market stagnation. Concluding with a look toward the 2020 election, the participants assess the political landscape as a coin flip between Donald Trump and Joe Biden, warning that long-term democratic stability is threatened by the widening wealth gap.

  13. All-In Podcast1h 32m

    E5: WHO's incompetence, kicking off Cold War II, China's grand plan, 100X'ing American efficiency

    David Sacks, Chamath Palihapitiya, David Friedberg

    In a recent episode of the "All In Podcast," hosts Jason Calacanis, Chamath Palihapitiya, David Sacks, and David Friedberg dissected global health governance, the US-China "Cold War II," and domestic political dynamics while ranking #10 on Apple's Tech Podcasts list. The quartet criticized the WHO's politicization regarding Roundup and COVID-19 transmission, outlined China's economic strategy to build a global productivity block through critical asset acquisition, and proposed US resilience through onshoring supply chains in biomanufacturing, energy, and technology. Additionally, the group assessed the 2020 election landscape, favoring Joe Biden's status-quo strategy while highlighting the urgent need for micro-schools and rapid testing to mitigate pandemic impacts on children.

  14. All-In Podcast1h 19m

    E4: Politicizing the pandemic, Police reform, Twitter vs Facebook with David Sacks & David Friedberg

    David Sacks, David Friedberg, Jason, Zuckerberg, Peter Thiel, John Bolton, Trump, Biden, Chamath Palihapitiya

    Chamath Palihapitiya, David Sachs, and David Friedberg analyze divergent pandemic safety strategies and the politicization of mask mandates while debating the efficacy of surveillance technology and the necessity of lockdowns. The group further critiques law enforcement militarization, the dynamics of cancel culture, and the free speech challenges posed by Big Tech's content moderation policies. Finally, they offer conflicting projections on the 2020 presidential election, weighing the impact of pandemic management, economic recovery, and potential vice-presidential selections on the likelihood of a Trump or Biden victory.

  15. All-In Podcast1h 7m

    E3: Modern Cold War, politicizing the pandemic & more with David Sacks & David Friedberg

    David Sacks, David Friedberg, Jason Calacanis, Chamath Palihapitiya

    Podcast hosts Jason Calacanis and Chamath Palihapitiya lead a roundtable with guests David Sacks and David Friedberg to analyze pandemic data, economic forecasts, and geopolitical shifts. The group agrees that the infection fatality rate is significantly lower than initially reported and warns of a prolonged two-to-three-year economic recovery marked by a divergence between tech and real sectors. They further predict that widespread mask adoption will allow economies to reopen while discussing the potential for decoupling from China and a long-term decline in San Francisco's prominence due to remote work trends.