Latest Interviews
Showing 211–225 of 2,630 transcripts.
Clear all filters- Milken Institute28 min
Future of Storytelling: A Conversation with Laurene Powell Jobs & Darren Walker | Global Conference
Laurene Powell Jobs, Darren Walker, Davis Guggenheim
Former Ford Foundation president Darren Walker has assumed the role of CEO at Anonymous Content, a strategic move intended to restore the studio's institutional stability following the grief-stricken vacancy left by founder Steve Golan. Walker and board member Lorraine Twohill position the leadership transition as a response to an evolving media landscape characterized by evaporating legacy revenue and a critical distribution bottleneck, leveraging the studio's independence from private equity to fund long-term, high-risk storytelling. Together, the new leadership emphasizes a renewed focus on human-centric narratives that bridge physical and digital divides, aiming to reset industry confidence through projects that prioritize universal resonance over activist didacticism.
Tom Mueller: SpaceX's #1 Employee Built the Merlin Engine. Now He's Building Impulse Space
Former SpaceX founding employee Tom Mueller founded Impulse Space to revolutionize intra-orbital transport with its fleet of advanced spacecraft, including the orbital transfer vehicle Mira and the heavy-lift Helios. The company leverages proprietary Nova Light alloy and additive manufacturing to produce the Deneb hydrocarbon engine and lightweight composite tanks, achieving performance metrics that could significantly boost payload delivery to the Moon and Mars. Currently advancing lunar infrastructure efforts through successful rendezvous tests and an active lander contract bid, Impulse Space combines in-house manufacturing with AI-driven design to support a future lunar economy.
- Bank of America25 min
GLP-1s are shrinking some appetites; broader use poses a prickly challenge
Peter Galbo, Jason Gerberry, TJ Thornton
As of May 2026, the U.S. GLP-1 market has reached 10 million treated patients and $28 billion in revenue while facing a deflationary pricing cycle driven by Medicare agreements and an upcoming surge of generic semaglutide competitors. This therapeutic expansion is displacing packaged food volume in snack and alcohol categories, forcing large-cap pharmaceutical firms to trade at depressed multiples as the market nears U.S. saturation and pivots toward international growth. Future value will increasingly depend on next-generation formulations targeting muscle preservation and adherence rates, with analysts forecasting a shift where international sales eventually comprise more than half of total category revenue.
- All-In Podcast30 min
Bill Ackman: Here's What the Market is MISSING
Bill Ackman, Chamath, Jason, David
Howard Ackman outlines a strategic evolution at Pershing Square toward concentrated long-term holdings in high-quality businesses, leveraging deep board involvement to counteract market short-termism and capitalize on undervalued legacy tech giants amidst AI-driven disruption. His approach extends to late-stage founder-led ventures like SpaceX and XAI, which he values through a venture capital lens of people and opportunity, while simultaneously repurposing the Howard Hughes Corporation into a "Berkshire 2.0" model that utilizes real estate cash flows to fund an insurance float for tax-efficient capital compounding. Ackman further explains how social media dynamics now enable persistent narratives to influence valuations, supporting a three-vehicle investment structure that includes a royalty-based management company, a public discount vehicle, and a transformed real estate holding to deliver sustained growth over decades.
- All-In Podcast32 min
OpenAI CFO Sarah Friar: IPO, AI Rivalries, New Device, and Spending $100B+ on Compute
OpenAI's CFO Sarah Fryer announced a historic $122 billion fundraising round and detailed a strategic pivot toward a 50-50 split between consumer and enterprise revenue while managing a global compute deficit through a $1 billion Michigan data center and diversified cloud partnerships. With ChatGPT serving over 900 million weekly users and a new "agentic" hardware interface set for release, the company aims to leverage vast user data to build a potent advertising model that prioritizes user intent and memory without compromising output neutrality. Looking ahead to 2030, OpenAI projects that rising infrastructure costs will be offset by improved model efficiency, maintaining its position as a single foundational AI utility across multiple global markets.
- Goldman Sachs26 min
The AI Investment Boom: When Will It Pay Off?
Jim Covello, Alison Nathan, George Lee
In a Goldman Sachs Exchanges episode recorded on May 26, 2026, Jim Cabello and George Lee analyze the divergence between surging AI technology and unproven economic returns. Cabello admits previous misjudgments regarding consumer adoption and hyperscaler spending patterns while warning that the current exclusive profitability of semiconductor firms creates an unsustainable market dynamic. The dialogue concludes that without evidence of enterprise-scale profitability within the next two years, the industry faces a potential correction where hyperscaler stocks are poised to outperform if capital expenditure moderates or profit distribution shifts upstream.
- Sequoia Capital40 min
Knowing What Your Customers Want, All the Time: Listen Labs' Alfred Wahlforss
Listen Labs leverages its database of 30 million participants to transition from AI-conducted interviews to generative agent simulations that predict individual customer preferences with up to 95% accuracy. Founder Alfred Walforce directs the platform to serve Fortune 500 clients like Microsoft and Chubbies by identifying specific product friction points and integrating insights directly into autonomous coding workflows. This approach creates a proprietary feedback loop where behavioral data refines agent models, allowing businesses to validate product decisions without the churn and cost of traditional market research.
- Milken Institute30 min
Science of Love: Conversation with Bumble CEO Whitney Wolfe Herd & Arthur Brooks | Global Conference
Whitney Wolfe Herd, Arthur Brooks, Savannah Sellers
Bumble and Harvard Kennedy School Professor Arthur C. Brooks collaborated to release a white paper arguing that successful offline marriages drive user growth while current app metrics exacerbate loneliness and social isolation. To counter declining relationship satisfaction and the atrophy of in-person social skills, the company is launching a Q4 product that replaces swipe mechanics with AI-driven screening for toxic personality traits and prioritizes immediate real-world meetings. This strategic shift redefines compatibility around shared core values rather than rigid filters and utilizes neurochemical insights to prove that genuine bonding requires physical presence over digital simulation.
- Bank of America22 min
Inflation and the inflation markets
Mark Capleton, Stephen Juneau, Alessandro Infelise-Zhou, Meghan Swiber
Strategists attribute the current surge in US inflation to Iran-related energy shocks, supply chain pressures, and AI-driven capital expenditure, while noting weaker fiscal stimulus compared to the pandemic era has kept demand-side inflation subdued. Although the Federal Reserve is likely to hold rates until labor market signals improve, forecasts now suggest a first 50-basis-point cut will not occur until the second half of 2026, whereas the Euro Area and UK anticipate earlier ECB rate hikes in mid-2025 followed by a slower cut cycle starting in 2027. Market positioning has shifted to short duration and long risk assets despite underpriced tail risks from prolonged conflict, as five-year inflation expectations remain anchored and European real rates continue to support a bullish bond stance.
- 80,000 Hours28 min
The Career Advice That's Quietly Ruining People's Lives
Benjamin Todd, Rob, Milo McGuire, Elizabeth Cox, Katy Moore
Eighty-thousand Hours challenges the conventional career advice to "follow your passion" by revealing through three decades of research that passion is often a result of meaningful work rather than a pre-existing guide. The organization proposes an alternative framework centered on five structural drivers—engaging work, helping others, competence, supportive colleagues, and basic needs—to systematically achieve career fulfillment without relying on unstable personal intuitions. By prioritizing skills that aid others over high-interest niches, individuals can avoid the stress of intense competition and secure greater long-term satisfaction regardless of income level.
- a16z33 min
The New Rule for Picking AI Winners | The a16z Show
Frontier AI firms like Anthropic and OpenAI are currently outpacing the combined revenue growth of major tech giants, with a projected collective run rate of $200 billion driving valuations toward $100 billion by September. While current enterprise adoption remains largely efficiency-focused, supply chain constraints are expected to persist until late 2028, preventing an oversupply bubble despite the rapid scaling of $5 trillion in data center capital expenditures. As venture strategies pivot to securing market leaders in a shrinking startup half-life, the industry is poised for a structural shift where dominant AI entities redefine public market dynamics and consumer engagement over the next decade.
- Y Combinator24 min
Why Two IIT Engineers Turned Down $550K Jobs To Build A Startup
GigaML, a Y Combinator-backed startup founded by IIT Kharagpur alumnus Varun and his Stanford-educated co-founder, has pivoted from EdTech to developing AI agents that achieve 60% to 70% support deflection rates for major clients like DoDash and DoorDash. The company addresses the enterprise bottleneck of manual configuration by launching "AI forward deployed engineers" that automatically iterate policies to improve business metrics, a strategy enabled by their "0.1% talent" recruitment philosophy and heavy reliance on human-coded expertise rather than sales teams. By leveraging the YC trust network to secure early contracts with eight-person operations, GigaML aims to unlock broader enterprise AI adoption through a generic automation layer that eliminates the need for extensive human engineering resources.
- 80,000 Hours36 min
Will AI cause mass unemployment? Maybe not.
Amid widespread fear of AI-driven job displacement, the event analyzes historical automation trends to reveal that wages may rise significantly until 2037 before facing a decline if full task automation is achieved without human oversight. Experts identify four categories of skills likely to increase in value, including complex physical tasks, AI deployment capabilities, and roles producing scalable goods, while warning against exclusive specialization in routine knowledge work. The presentation concludes by advising professionals to cultivate transferable leadership and technical abilities that bridge human decision-making with AI efficiency to navigate a shifting labor market.
- Sequoia Capital25 min
Neuralink's DJ Seo: Inside the Race to Connect Brains and AI
DJ Seo, Shaun Maguire, Sean McGuire
Neuralink is advancing its brain-computer interface technology through the deployment of two therapeutic products, Telepathy and Blindsight, to restore motor function and vision for patients with conditions like ALS and total blindness. The company has implanted its devices in over 20 human participants and reports successful trials where users regained computer control or visual perception, supported by a strategy of vertical integration and an "all-green light" engineering framework. Founder J.D. McGuire envisions these medical breakthroughs as a precursor to creating an "exocortex" that merges human intent with AI, pending regulatory approval for broader non-medical augmentation.
- Goldman Sachs34 min
‘Complexity is Our Friend’: James Brocklebank on Advent's Private Equity Strategy
James Brocklebank, Alison Mass
James Brockelbank details Advent's $100 billion strategy of navigating complex regulatory environments in Europe and expanding into Asia-Pacific through a focus on transformational carve-outs and pure private equity specialization. Facing slowed exit realizations, the firm has integrated proprietary AI tools like "Advent GPT" into its investment committees while shifting toward strategic buyers to manage capital returns. Brockelbank emphasizes that despite these technological advancements, deep human relationship-building and a culture of "healthy paranoia" remain the critical differentiators for identifying high-quality opportunities in volatile markets.