Latest Interviews
Showing 121–135 of 206 transcripts.
Clear all filters- Goldman Sachs36 min
How Small Business Owners Are Dealing With Worker Shortages, Inflation and Supply Chain Delays
Joe Wall, Allison Nathan, Ruby Bugarin, Kari Parker, Rosemary Swirk
Goldman Sachs' "10,000 Small Businesses Voices" initiative released September survey data revealing a sharp 29-point decline in small business optimism driven by the Delta variant, inflation, and severe workforce shortages. The report details how specific sectors face record operating costs and supply chain delays, while Black-owned businesses struggle with lower capital confidence and depleted cash reserves compared to the broader market. In response to these challenges, the organization is calling for a permanent low-interest loan program and federal procurement reforms to address the systemic lack of representation and resource disparity.
- Milken Institute1h 32m
Accelerating Securitization in Africa to Finance the SDGs
Alison Harwood, Lade Araba, Samuel Chasia, Juan Pablo de Mollein, John Schellhaus, Sam Chasia
The Milken Institute has launched the African Securitization Alliance, bringing together regulatory bodies from Kenya, Ghana, Uganda, and Côte d'Ivoire to mobilize private capital for Sustainable Development Goals. Participants will utilize a framework of internal and external credit enhancement mechanisms, such as tranching and third-party guarantees from entities like GARANTCo, to mitigate risk and improve market access. Upcoming activities include a specialized workshop in Ghana and a strategic shift toward replicable structures in renewable energy and affordable housing to overcome data gaps and legal barriers.
- Milken Institute1h 31m
Small Business Community: What Happened to Mom and Pop?
Nigel Duara, Lenore Estrada, Isabella Casillas Guzman, Eugene Cornelius, Jr., Carolina Martinez, Mark J. Robertson, Sr., David Lesher
Co-hosted by CalMatters and the Milken Institute, this strategic discussion examined the critical recovery challenges facing California's four million small businesses with special attention to the stark disparities affecting communities of color and women-owned enterprises. Featuring newly appointed SBA Director Isabella Casillas Guzman, the event analyzed how the agency's portfolio expansion to over $1 trillion was initially skewed by banking biases, prompting a pivot toward a "Five C's" framework that prioritizes coaching, diverse capital, and community navigation to address exclusion. Looking forward, the SBA is repositioning to connect small businesses with the $500 billion federal infrastructure marketplace while implementing a $100 million Community Navigator pilot to streamline access for underserved entrepreneurs.
- Goldman Sachs20 min
The Global Chip Shortage: Impact, Outlook and Recovery
Toshiya Hari, Kota Yuzawa, Rod Hall, Allison Nathan
Driven by pandemic-induced demand surges and supply chain bottlenecks that began in early 2020, the global semiconductor shortage peaked in mid-2021 before projections indicate a gradual normalization through 2022. The automotive and consumer electronics sectors faced significant disruption, with the auto industry losing $15–$20 billion in operating profits while hardware giants like Apple and Cisco capitalized on remote-work trends. This crisis has triggered a structural shift toward long-term contracts, government-backed domestic manufacturing investments by Intel and TSMC, and a move away from just-in-time inventory strategies to ensure future supply resilience.
- Goldman Sachs24 min
The European Recovery: Here to Stay?
Allison Nathan, Jari Stehn, Richard Privorotsky, Yari Shteyn, Rich Pivorotsky
Driven by rapid vaccination rates and a significant fiscal stimulus package, the Euro Area and UK are projected to see GDP growth rates of 5.4% and 8.1% respectively in 2021, outpacing global consensus. While the ECB maintains an accommodative monetary stance with no rate hikes anticipated until 2025, European equity markets have rallied with cyclical sectors leading a shift in investor flows away from defensive positions. Despite persistent political risks in Italy, France, and Germany, the outlook remains positive as temporary inflationary pressures are expected to subside by late 2021, allowing structural reforms to drive medium-term expansion.
- Goldman Sachs18 min
Copper is the New Oil
Goldman Sachs identifies copper as the "new oil" essential for global net-zero targets, projecting that green economy adoption will drive demand to nearly 6 million tons by 2030 while creating a structural deficit of over 8 million tons. Despite price forecasts reaching $15,000 per ton by 2025, major mining producers remain hesitant to initiate new greenfield projects due to prolonged permitting, high costs, and a conservative post-2010 balance sheet strategy. Consequently, the market faces an irreversible supply crunch in the mid-2020s that will likely decouple copper prices from traditional Chinese cycles and trigger a sustained multi-year bull market.
- Milken Institute1h 2m
Lessons Learned from COVID-19: Are There Silver Linings for Biomedical Innovation?
Esther Krofah, Francis Collins, Richard Moscicki, Ellen Sigal, Janet Woodcock
Hosted by Faster Cures, a webinar convened NIH officials and industry leaders to analyze the COVID-19 pandemic's acceleration of biomedical innovation, highlighting achievements such as the ACTIV partnership's master protocols and the RADx initiative's diagnostic scaling. The discussion detailed how the crisis forced a shift toward competitive collaboration, decentralized trials, and the successful achievement of diverse vaccine trial enrollment, while simultaneously exposing critical infrastructure gaps in clinical trial execution and real-world data integration. Panelists concluded with a consensus that emergency-driven reforms must be institutionalized through permanent policy changes and public-private partnerships to sustain preparedness for future health threats.
- Goldman Sachs37 min
What the American Rescue Plan Means for the Economy, Markets, Corporations & Investors
Alec Phillips, Amelia Garnett, Susie Scher, Ashish Shah, Jake Seward
Following the enactment of the $1.84 trillion American Rescue Plan, economists revised U.S. GDP growth forecasts to 8% for 2021 and anticipate further infrastructure legislation funded by corporate tax hikes. Market participants are executing a sector rotation toward value assets while corporate finance activity surges, driven by a $9 trillion pandemic stimulus total that has revitalized M&A and equity issuance. Although inflation expectations and rising yields present headwinds, experts project improved municipal credit quality and consumer balance sheets as stimulus funds flow into the economy through 2022.
- Milken Institute1h 17m
Part 1: A Conversation with New Jersey Governor Phil Murphy
Phil Murphy, Edward Greissing, Lynn Goldman, Judith Monroe, David Rhew, Alyssa Rieder
New Jersey Governor Phil Murphy detailed the state's data-driven pandemic response, highlighting the establishment of a massive PPE stockpile, the training of surge healthcare workers, and the creation of a $100 million relief fund for small businesses. Alongside First Lady Tammy Murphy, the administration launched the "Nurture NJ" initiative to address systemic disparities in Black maternal infant mortality while advocating for a strengthened national public health infrastructure and increased federal investment in the CDC and NIH. The broader panel emphasized that future preparedness requires modernizing data infrastructure, closing the digital divide, and implementing a holistic strategy that integrates health equity into all policy decisions to prevent a return to pre-pandemic inequities.
- Milken Institute53 min
Predicting Pandemics: Mobilizing an Active Global Surveillance System
Dan Diamond, Francis deSouza, Margaret Hamburg, John Nkengasong
Despite unprecedented advances in viral sequencing speed during the COVID-19 pandemic, experts identified critical systemic gaps in global pathogen surveillance that relied on serendipitous discovery rather than proactive networks. Highlighting stark disparities between nations like South Korea and underserved regions in Africa, leaders such as Francis D'Souza and Dr. Hamburg outlined a $100 million Genomics Initiative and advocated for a sustainable public-private partnership to fund a "One Health" approach. This collaborative strategy aims to integrate human, animal, and environmental monitoring through modern genomic technologies, ensuring real-time detection of emerging threats while addressing the political and structural barriers that hindered previous pandemic responses.
- Y Combinator4 min
Harj Taggar - How Startups can Compete with FAANG Companies when Hiring Employees
Harj, a Y Combinator partner, details three competitive strategies for startups to secure talent against major tech firms by leveraging speed, personalized engagement, and impact. Startups can outpace bureaucratic delays by accelerating hiring to same-day outreach and offering immediate decisions, while simultaneously distinguishing their culture through high-volume, personalized follow-ups that make candidates feel uniquely valued. Furthermore, the approach emphasizes the tangible impact of startup contributions compared to the project cancellations common in large corporations, using founder anecdotes to highlight the frustration of wasted effort at bigger companies.
- Lex Fridman1h 13m
Lex Fridman: Ask Me Anything - AMA January 2021 | Lex Fridman Podcast
Lex delves into the philosophical necessity of integrating suffering into artificial consciousness to achieve genuine human-like intelligence while exploring how his immigrant journey shaped his view on isolation and connection. He addresses diverse topics ranging from alien inquiry strategies and medical-to-technology career pivots to his personal optimization through a meat-based diet and resilience against betrayal. Throughout the discussion, he advocates for optimistic long-term thinking, arguing that hope and the willingness to endure struggle are essential for engineering meaningful AI systems and sustaining deep work.
- Goldman Sachs19 min
Companies Continue to Turn to SPACs for Greater Flexibility
The 2020 SPAC market surged to over 200 IPOs raising $100 billion, driven by flexible terms and a broadening investor base that included traditional mutual funds. Following a temporary correction caused by supply fatigue in late 2020, the sector stabilized by December with 10 to 15 successful combinations, signaling renewed momentum for 2021. Looking forward, the industry is expanding into global markets and sectors like PropTech and auto tech, with Goldman Sachs noting 80 active SPACs poised to facilitate an additional $500 billion in M&A activity over the next two years.
- Lex Fridman2h 14m
Michael Mina: Rapid Testing, Viruses, and the Engineering Mindset | Lex Fridman Podcast #146
Dr. Michael Mina advocates for scaling rapid antigen testing as a primary solution to halt community transmission, arguing that regulatory classifications currently treat these low-cost public health tools as expensive medical devices. He proposes establishing a "Public Health Engineering" framework to monitor viral spread through anonymous plasma data while warning of severe pandemic risks posed by influenza evolution and engineered pathogens. This approach seeks to replace reactive medical protocols with scalable, individual-driven data collection to mitigate future biological threats.
- Lex Fridman17 min
DeepMind solves protein folding | AlphaFold 2
DeepMind's AlphaFold 2 has solved the fifty-year protein folding challenge by employing attention-based transformer architectures to achieve prediction accuracy rivaling expensive experimental methods. This system outperformed its predecessor and all competitors at the 2018 CASP competition, generating precise three-dimensional structures for millions of proteins despite the astronomical complexity of folding configurations. Experts anticipate this breakthrough will catalyze multiple Nobel Prizes and transform fields ranging from drug discovery to materials science by enabling the computational design of proteins for treating misfolding diseases and engineering agricultural and industrial applications.