Latest Interviews
Showing 226–240 of 1,099 interview transcripts.
Clear all filters- RAISE Summit29 min
Anjney Midha of a16z: Algorithmic Independence The Next Frontier in National Infrastructure
The event defines Sovereign AI as a four-tiered strategy for achieving technical and cultural independence, utilizing methods like mid-training to correct deep-seated biases rather than simple fine-tuning. As nations transition from closed-source prototypes to open-source models, a geopolitical divide is emerging where "hypercenters" like the US and China face competition from Europe's "Mistral Compute" initiative while non-hypercent nations adopt joint-venture models to retain value. The discussion concludes with predictions that general-purpose robotics and universal computer use will mature within two years, leveraging Europe's specific strengths in computer vision to secure its strategic position in the global AI landscape.
- RAISE Summit34 min
Bruno Gagliardo, Global Head of Data & AI @ Sanofi : Molecule to Market, Driving AI Transformation
Bruno Gagliardo, Larry Orimoloe
Sanofi CEO Bruno Gagliardo unveiled a five-year strategy to transform the pharmaceutical giant into a "pharma tech" leader by migrating 85,000 employees to a cloud-based data mesh architecture powered by large-scale AI. The initiative integrates the RAISE governance framework and a $100 million impact barrier to mitigate hallucination risks while accelerating drug discovery and regulatory submissions from 19 weeks down to five. This cultural shift prioritizes AI augmentation over replacement, utilizing agentic systems and a hybrid build-or-buy approach to deliver substantial efficiency gains across research, manufacturing, and commercial operations.
- All-In Podcast27 min
Alibaba's Joe Tsai on US-China Rivalry, AI Future, Owning the Nets/Liberty, Caitlin Clark's Impact
Joe Tsai, Caitlin Clark, Chamath, Jason, Friedberg
Business leader Joe Satt outlines Alibaba's strategic pivot toward AI-driven efficiency, highlighting a 14.5% stock surge following the Qwen 2.5 Max launch and a corporate culture where 30% of engineering code is now AI-generated. He contrasts U.S. and Chinese market dynamics by discussing the WNBA's surge in popularity driven by Caitlin Clark while arguing that U.S.-China relations represent necessary economic competition rather than bitter rivalry, noting China's 50% corporate AI adoption rate. Satt further critiques structural differences in American versus Chinese education and governance, asserting that the future of technological progress relies on cooperation in fields like medicine rather than a zero-sum race for dominance.
- Milken Institute36 min
Influence to Shape Platforms for Good | Asia Summit 2025
Ross Butler, Bhumi Pednekar, Curtis S. Chin
Actors Bhumi Pednekar and Ross Butler discuss their respective careers of dismantling stereotypes in Indian and Hollywood cinema while highlighting the societal pressures to pursue traditional professions over creative arts. Beyond entertainment, both advocates emphasize the transformative power of social media for disaster relief and mental health awareness, with Pednekar leading UNDP climate initiatives and Butler championing cross-cultural co-productions in Southeast Asia. Looking forward, the duo plans to collaborate on a project bridging Indian and Asian narratives while mentoring emerging talent to redefine regional storytelling globally.
- Goldman Sachs44 min
Memorial Sloan Kettering Cancer Center’s CEO on the Future of Cancer Treatment
Selwyn M. Vickers, Brian Robinson, Dr. Selwyn Vickers
Memorial Sloan Kettering leverages its vast biobank and dual expertise in computational oncology to drive a "golden era" of cancer treatment, where AI-driven predictive models and breakthroughs in immunotherapy have transformed survival rates for aggressive malignancies. Concurrently, the institution confronts rising youth cancer incidence and systemic health inequities by developing accessible genetic screening tools and deploying low-infrastructure immunotherapy protocols globally. These clinical and technological advances are grounded in a leadership philosophy that prioritizes professional excellence to dismantle socioeconomic barriers and improve care access for underserved populations.
- Milken Institute30 min
A Conversation with Saweetie: Harnessing Philanthropy to Build Financial Futures | Asia Summit 2025
Saweetie, Diamonté "Saweetie" Harper, Richard Lui
Multi-platinum rapper and entrepreneur Sweetie discusses her trajectory from baking cookies as a child to securing high-profile partnerships with brands like McDonald's and Calvin Klein while maintaining an authentic leadership style. She details the founding of the I See Baby Foundation, which aims to instill financial literacy in underrepresented youth by leveraging her personal financial lessons and her grandmother's advice. The conversation concludes with her strategic vision to build a decade-long infrastructure that teaches communities how to live educated, self-determined lives through a diverse, women-led team.
- a16z43 min
The Person Who Runs HR For 2 Million Federal Workers
Katherine Boyle, Scott Kupor, Greg Barbaccia
The administration is executing a sweeping overhaul of the federal workforce to secure national leadership in the AI race, projecting a reduction of 300,000 civilian employees while dismantling 43 years of hiring barriers to mandate technical skill testing. This strategy shifts performance evaluations toward a forced distribution model and replaces risk-averse culture with outcome-based efficiency, targeting a critical talent gap by recruiting early-career professionals and private sector executives for short-term secondments. Key initiatives include centralizing citizen data through a "One Government" portal, deploying generative AI tools like ChatGPT on government desktops, and restructuring contractor oversight to prevent cost sprawls driven by non-technical management.
- All-In Podcast23 min
Rick Caruso on California’s Collapse: Broken Leadership, LA Wildfire Failures & the Fix
Rick Caruso, Karen Bass, Chamath, Jason
In the wake of the Palisades fires, developer Rick Caruso contrasts his private sector emergency preparations against the city's failures, blaming incompetent governance under Mayor Karen Bass for the destruction of 90% of the homes. Caruso argues that ideological politics have paralyzed local authorities, leading him to propose a competency-based administration that enforces zero tolerance for street encampments while simultaneously securing federal aid and infrastructure upgrades for rebuilding. As he evaluates potential political bids, Caruso emphasizes that California must prioritize practical solutions over political maneuvering to reverse systemic decay and restore the state's status as a national leader.
- All-In Podcast25 min
Arm CEO Rene Haas on AI: Nvidia Lessons, Intel’s Decline and the US-China Chip War
Rene Haas, Jensen Huang, David, Jason
Following a landmark September IPO that vaulted its valuation to $150 billion, Arm is leveraging its foundational IP to transition from a smartphone architecture provider into a strategic partner for Nvidia and a supplier for the emerging "Physical AI" robotics market. Chief Executive Officer Rene Haas is aggressively reshaping the company's global culture and engineering focus to accelerate speed-to-market, while explicitly navigating complex geopolitical frictions and supply chain constraints to maintain a unified global ecosystem. With its architecture underpinning critical advances in both data center training chips and energy-efficient endpoint inference, Arm is positioning itself to dominate a diverging semiconductor landscape where specialized hardware will define future AI capabilities.
- RAISE Summit21 min
Alexis Ohanian, Founder, 776, Reddit & Victorien Tixier, CEO, ScorePlay: The Future of AI in Sports
Alexis Ohanian, Victorien Tixier, Vic
At an industry conference, Reddit co-founder Alexis Ohanian interviewed Scoreplay CEO Vic LaRosa to discuss how artificial intelligence will commoditize content production while elevating live sports as the premier vehicle for authentic, real-time human connection. Their dialogue highlighted Scoreplay's mission to replace legacy infrastructure with centralized AI automation for media asset management, a strategy designed to unlock global market reach through instant localization and data-driven camera placement. The conversation further emphasized a strategic pivot toward women's sports, where Ohanian argues that re-underwriting assets from first principles and leveraging digital-first storytelling will drive exponential valuation growth and reshape traditional league dynamics.
- All-In Podcast31 min
Inside the GLP-1 Gold Rush: Eli Lilly CEO on New Breakthroughs, Addiction & Mental Health, Pricing
Dave Ricks, Chamath, Jason, Friedberg
Eli Lilly CEO David Ricks has steered the company to an 860% market capitalization increase and record-breaking Mounjaro sales by leveraging a massive research workforce and aggressive manufacturing expansion to secure global dominance in GLP-1 therapies. While the firm faces capital shortages in the broader biotech sector, it is diversifying its pipeline beyond weight loss to address brain disorders and developing oral formulations to improve accessibility without compromising the high R&D reinvestment model Ricks defends. Personalized by Ricks' own successful treatment, the company balances aggressive clinical innovation with strategic supply chain controls to maintain its competitive edge against emerging international rivals.
- Goldman Sachs23 min
Will macro fuel more stock gains?
Analysts project the Federal Reserve will implement two additional rate cuts by year-end to address labor market risks, targeting a terminal rate near 3% as the economy navigates mixed employment signals and structural uncertainties. This easing cycle, expected to conclude by December 2026, aims to support risk assets and sustain growth while keeping inflation pressures contained amid a bearish outlook for oil and tariff impacts. Despite valuation concerns and skepticism regarding AI capital expenditure sustainability, the prevailing view suggests that resilient fundamentals and policy shifts will maintain upside momentum for the broader market through 2026.
- All-In Podcast29 min
Eric Schmidt on AI, the Battle with China, and the Future of America
Eric Schmidt, Chamath, Jason, Friedberg
Former Google CEO Eric Schmidt outlines a strategic framework where the immediate AI revolution remains underhyped and distinct from the imminent arrival of autonomous agents, while warning that Western nations must counter China's aggressive pivot toward open-weight models and advanced robotics. Schmidt anticipates a future military doctrine defined by millions of AI-driven drones that create high-deterrence stalemates rather than traditional combat, driven by the obsolescence of fixed military infrastructure. Simultaneously, he emphasizes that US geopolitical resilience depends on leveraging domestic capital markets and releasing smaller open-source models to maintain control over handheld device proliferation amidst global demographic declines.
- Y Combinator42 min
Why Now Is The Best Time To Build In Crypto
Led by Base founder Jesse Pollock, industry leaders declare a new golden age for crypto building driven by mature infrastructure that has reduced transaction costs to near zero and achieved regulatory clarity through legislation like the Genius Act. This environment enables a shift from legacy financial systems to programmable, censorship-resistant networks where stablecoins facilitate global access and tokenization allows creators to retain ownership of their capital. As a result, Coinbase and Y Combinator are prioritizing technical founders who apply these scalable Layer 2 architectures to solve real-world problems, signaling a surge in high-quality engineering teams ready to integrate AI and financial services over the next 18 months.
- Sequoia Capital45 min
Why Businesses Are Rejecting the AI They’ve Asked For ft Agency CEO Elias Torres
Elias Torres, Sonya Huang, Pat Grady
Elias Torres leverages his experience founding Drift and leading HubSpot's platform rebuild to launch Agency, an AI-native company dedicated to automating entire customer workflows rather than merely assisting human agents. The venture targets enterprise clients by challenging the market's demand for perfect AI accuracy, instead promoting a model that delivers broad functionality with 10-30% efficiency gains while relying on fewer than 100 employees to scale operations. Torres aims to build a $1 billion revenue entity by deprogramming businesses from manual dependency and hiring talent driven by grit and hunger over traditional credentials.